| 영문 | aldosterone | 한글 | 알도스테론 |
|---|---|---|---|
| 설명 | 콩팥 위에 있는 작은 삼각형의 기관인 부신의 겉질에서 분비되는 호르몬. 체내의 물과 전해질의 균형에 기여한다. 신장에 작용해서 물과 나트륨의 흡수를 촉진하고 칼륨을 분비하게 한다. 즉 이 호르몬의 작용에 의하여 체내의 물과 나트륨의 양은 증가하고 칼륨의 양은 감소한다. 콩팥에서 혈류와 혈압을 감지하는 세포인 치밀반점(macula densa)과 토리곁세포(JG Cell)에서 혈류와 혈압의 저하가 있을 경우에 레닌(renin)이라는 물질이 분비된다. 이 레닌이라는 물질은 혈중에 존재하는 안지오텐시노겐이라는 물질을 안지오텐신 I으로 변화시키고 이 물질은 안지오텐신 I 전환효소에 의해서 안지오텐신 II라는 물질로 된다. 이 물질은 강력하게 혈관을 수축시키고 이로 인해서 혈압이 올라가는 동시에 부신을 자극하여 알도스테론을 분비하게 한다. 이 레닌-안지오텐신-살도스테론의 체계는 몸속의 혈압이 떨어지거나 혈액의 양이 줄어드는 경우에 작용해서 혈압을 올리는 작용을 한다.  |
||
| AChRs | Acetylcholine Receptors |
|---|---|
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| RAA | Renin-Angiotensin-Aldosterone |
| AER | abduction/external rotation; acoustic evoked response; acute exertional rhabdomyolysis; agranular en... |
| AIP | acute idiopathic pericarditis; acute infectious polyneuritis; acute intermittent porphyria; aldoster... |
| A | Aldosterone |
|---|---|
| ALD | Aldosterone |
| ALDO | Aldosterone |
| APA | Aldosterone Producing Adenoma |
| ASR | Aldosterone Secretion Rate |
| receptors, aldosterone | Cytoplasmic proteins that specifically bind aldosterone and mediate its cellular effects. The aldosterone-bound receptor acts in the nucleus to regulate the transcription of specific segments of DNA. (12 Dec 1998) |
|---|
| aldosterone | <endocrinology, hormone> A steroid hormone produced by the adrenal cortex, that controls salt and water balance in the kidney. Abnormally high levels of this hormone cause sodium retention, high blood pressure, heart rhythum irregularities and possibly paralysis (18 Nov 1997) |
|---|---|
| aldosterone antagonist | An agent that opposes the action of the adrenal hormone aldosterone on renal tubular mineralocorticoid retention; these agents, e.g., spironolactone, are useful in treating the hypertension of primary hyperaldosteronism, or the sodium retention of secondary hyperaldosteronism. (05 Mar 2000) |
| aldosterone antagonists | Compounds which inhibit or antagonise the biosynthesis or actions of aldosterone. (12 Dec 1998) |
| renin-angiotensin-aldosterone system | The hormones, renin, angiotensin, and aldosterone work together to regulate blood pressure. A sustained fall in blood pressure causes the kidney to release renin. This is converted to angiotensin in the circulation. Angiotensin then raises blood pressure directly by arteriolar constriction and stimulates adrenal gland to produce aldosterone which promotes sodium and water retention by kidney, such that blood volume and blood pressure increase. (05 Mar 2000) |
| hormone, aldosterone | Hormone produced by the outer portion (cortex) of the adrenal gland that regulates the balance of water and electrolytes (ions such as potassium and sodium) in the body. Aldosterone encourages the kidney to excrete potassium into the urine and to retain sodium, thereby retaining water. Aldosterone is classified as a mineralocorticoid hormone. (12 Dec 1998) |
| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |
| ANP receptors | Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains. (05 Mar 2000) |
| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| beta-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2). (05 Mar 2000) |
| mannose-6-phosphate receptors | Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) |
| receptors, adrenergic | Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of g-proteins with which they bind; this scheme does not respect the alpha-beta distinction. (12 Dec 1998) |
| receptors, adrenergic, alpha | One of the two major pharmacological subdivisions of adrenergic receptors. The alpha-beta distinction was originally based on cellular effects of receptor activation but now relies on the relative affinities for certain synthetic ligands. Alpha-adrenergic receptors are further subdivided into several subclasses based on studies of endogenous and cloned receptors. (12 Dec 1998) |
| receptors, adrenergic, alpha-1 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-1 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist phenylephrine and the antagonist prazosin. They are widespread, with clinically important concentrations in the liver, the heart, vascular, intestinal, and genitourinary smooth muscle, and the central and peripheral nervous systems. (12 Dec 1998) |
Synonyms : Aldosterone Receptor, Receptor, Aldosterone
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|