| AChRs | Acetylcholine Receptors |
|---|---|
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| Ig | Immuno-globulin IgA; Immuno-globulin A; (27)(30)60(100) - (170)(80)(250)380 mg/dL |
| AGA | accelerated growth area; allergic granulomatosis and angiitis; American Gastroenterological Associat... |
| AHuG | aggregated human IgG |
| HA-IgG | Heat-aggregated IgG |
|---|---|
| IgG RF | IgG rheumatoid factor |
| PA-IgG | Platelet associated IgG |
| IgGBF | IgG binding factor |
| IgG | Immunoglobulin G |
| receptors, IgG | Specific molecular sites on the surface of various cells, including B-lymphocytes and macrophages, that combine with iggs. Three subclasses exist: fc gamma ri (the CD64 antigen, a low affinity receptor), fc gamma rii (the CD32 antigen, a high affinity receptor), and fc gamma riii (the CD16 antigen, a low affinity receptor). (12 Dec 1998) |
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| IgG | <immunology> The classical immunoglobulin class also called 7S IgG (150 kD). Composed of two identical light and two identical heavy chains, the constant region sequence of the heavy chains being of the type. The molecule can be described in another way as being composed of two Fab and an Fc fragment. The Fabs include the antigen combining sites, the Fc region consists of the remaining constant sequence domains of the heavy chains and contains cell binding and complement binding sites. Immunoglobulin Gs act on pathogens by agglutinating them, by opsonising them, by activating complement mediated reactions against cellular pathogens and by neutralising toxins. They can pass across the placenta to the foetus as maternal antibodies, unlike other Ig classes. In humans four main subclasses are known, IgG2 differs from the rest in not being transferred across the placenta and IgG4 does not fix complement. Immunoglobulin G is present at 8-16 mg/ml in serum. Synonym: gamma globulin. (30 Mar 1998) |
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| IgG deficiency | A dysgammaglobulinaemia characterised by a deficiency of IgG. (12 Dec 1998) |
| IGG-horseradish peroxidase | <chemical> Synonym: IgG-hrp (26 Jun 1999) |
| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |
| ANP receptors | Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains. (05 Mar 2000) |
| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| beta-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2). (05 Mar 2000) |
| mannose-6-phosphate receptors | Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) |
| receptors, adrenergic | Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of g-proteins with which they bind; this scheme does not respect the alpha-beta distinction. (12 Dec 1998) |
| receptors, adrenergic, alpha | One of the two major pharmacological subdivisions of adrenergic receptors. The alpha-beta distinction was originally based on cellular effects of receptor activation but now relies on the relative affinities for certain synthetic ligands. Alpha-adrenergic receptors are further subdivided into several subclasses based on studies of endogenous and cloned receptors. (12 Dec 1998) |
| receptors, adrenergic, alpha-1 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-1 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist phenylephrine and the antagonist prazosin. They are widespread, with clinically important concentrations in the liver, the heart, vascular, intestinal, and genitourinary smooth muscle, and the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, adrenergic, alpha-2 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-2 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist clonidine and the antagonist yohimbine. They are found on pancreatic beta cells, platelets, and vascular smooth muscle, as well as both pre- and postsynaptically in the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, adrenergic, beta | One of the two major pharmacologically defined classes of adrenergic receptors. The alpha-beta distinction was originally based on the cellular effects of receptor activation but now relies on the relative affinities for characteristic synthetic ligands. Beta adrenergic receptors are further subdivided based on information from endogenous and cloned receptors. (12 Dec 1998) |
Synonyms : CD 16 Antigens, CD 32 Antigens, CD 64 Antigens, CDw32 Antigens, Fc gamma RI, Fc gamma RII, Fc gamma RIII, Immunoglobulin G Receptor, Leu-11 Antigens, Antigens, CD 16, Antigens, CD 32, Antigens, CD 64, Antigens, CDw32, Antigens, Leu-11, Leu 11 Antigens, gamma RI, Fc
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