| ¿µ¹® | mutation | ÇÑ±Û | µ¹¿¬º¯ÀÌ |
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| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
|---|---|
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| LOR | long open reading frame; lorazepam; loricrin; loss of righting reflex |
| LORF | long open reading frame |
| ARMS | Amplification Refractory Mutation System |
|---|---|
| MFD | Mutation frequency decline |
| RIP | Repeat Induced Point mutation |
| RSM | Restriction Site Mutation |
| SMART | Somatic Mutation And Recombination Test |
| reading-frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
|---|---|
| frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| frameshift | <molecular biology> A shift in the reading frame used to translate the base sequence of DNA or mRNA. It is caused by the addition or deletion of one or more of the bases, resulting in an alternative peptide being formed. (17 Dec 1997) |
| frameshift mutagen | <molecular biology> A mutagen, such as an acridine derivative, that causes a frameshift mutation; codons (base triplets) are read out of phase and different amino acids are made. (05 Mar 2000) |
| albumin Reading | Types of human serum albumin, distinguished by characteristic mobility patterns on electrophoresis; each type is due to a mutation of a gene controlling albumin synthesis; the mutant genes are codominant with the normal gene for albumin A, and the group forms a system of genetic polymorphism; types include: albumin b (slow), found occasionally in persons of European ancestry; albumin Ghent (fast), found first at Ghent, Belgium; albumin Mexico (slow), found in Indians of Mexico and the southwestern United States; albumin Naskapi (fast), found in the Naskapi and other Indians of northern North America; and albumin Reading (fast), found first at Reading, England. (05 Mar 2000) |
| blocked reading frame | A sequence of DNA that cannot be translated into a viable protein; usually due to the interruption by one or more termination codons. Synonym: closed reading frame. (05 Mar 2000) |
| reading frame | One of the three possible ways of reading a nucleotide sequence. As the genetic code is read in nonoverlapping triplets (codons) there are three possible ways of translating a sequence of nucleotides into a protein, each with a different starting point. For example: given the nucleotide sequence: AGCAGCAGC, the three reading frames are: AGC AGC AGC, GCA GCA, CAG CAG. (18 Nov 1997) |
| reading frame, open | An open reading frame in DNA has no termination codon, no signal to stop reading the nucleotide sequence, and so may be translated into protein. (12 Dec 1998) |
| reading frames | The sequence of codons by which translation may occur. A segment of mRNA 5'auccga3' could be translated in three reading frames, 5'auc.. Or 5'ucc.. Or 5'ccg.., depending on the location of the start codon. (12 Dec 1998) |
| mind-reading | The knowledge or communication by one person with the mental processes of another through channels other than known physical or perceptual processes. (12 Dec 1998) |
| closed reading frame | A sequence of DNA that cannot be translated into a viable protein; usually due to the interruption by one or more termination codons. Synonym: closed reading frame. (05 Mar 2000) |
| open reading frame | <molecular biology> A reading frame in a sequence of nucleotides in DNA that contains no termination codons and so can potentially translate as a polypeptide chain. (18 Nov 1997) |
| open reading frames | Reading frames where successive nucleotide triplets can be read as codons specifying amino acids and where the sequence of these triplets is not interrupted by stop codons. (12 Dec 1998) |
| overlapping reading frame | <molecular biology> Start codons in different reading frames which generate different polypeptides from the same DNA sequence. (09 Oct 1997) |
| unidentified reading frame | <molecular biology> A reading frame in a sequence of nucleotides in DNA that contains no termination codons and so can potentially translate as a polypeptide chain. (18 Nov 1997) |
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