| KW change | Keith Wagener change |
|---|---|
| MCD | 1) Minimal Change Disease 2) Menstrual Cycle Day |
| MCL | Minimal Change Disease |
| MCN | Minimal Change Nephrotic syndrome = MCNS |
| MCNS | Minimal Change Nephrotic Syndrome = MCN |
| CGI-C | Clinical Global Impression of Change |
|---|---|
| FAC | Fractional area change |
| HSC | Health System Change |
| MCD | Minimal change disease |
| MCN | Minimal change nephropathy |
| rachitic | To do with rickets, a disease caused by Vitamin D deficiency. (18 Nov 1997) |
|---|---|
| rachitic diet | A diet that will induce rickets in susceptible experimental animals. (05 Mar 2000) |
| rachitic pelvis | A contracted and deformed pelvis, most commonly a flat pelvis, occurring from rachitic softening of the bones in early life. (05 Mar 2000) |
| rachitic rosary | A row of beading at the junction of the ribs with their cartilages, often seen in rachitic children. Synonym: beading of the ribs. (05 Mar 2000) |
| rachitic scoliosis | Scoliosis occurring as a result of rickets. (05 Mar 2000) |
| Armanni-Ebstein change | Glycogen vacuolization of the loops of Henle, seen in diabetics before the introduction of insulin. Synonym: Armanni-Ebstein change. (05 Mar 2000) |
| Baggenstoss change | Distention of pancreatic acini by proteinaceous secretion, seen in dehydration. (05 Mar 2000) |
| change | An alteration; in pathology, structural alteration of which the cause and significance is uncertain. Synonym: shift. (05 Mar 2000) |
| change of life | Colloquialism for menopause, climacteric. (05 Mar 2000) |
| chemical change | A process in which one or more substances are changed into one or more different substances. (09 Oct 1997) |
| minimal-change disease | <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown. Risk factors include a history for a immune disorder, recent immunisation or a bee sting. Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented. Synonym: lipoid nephrosis (27 Sep 1997) |
| minimal-change nephrotic syndrome | <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown. Risk factors include a history for a immune disorder, recent immunisation or a bee sting. Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented. Synonym: lipoid nephrosis (27 Sep 1997) |
| conformational change | <cell biology> Alteration in the shape usually the tertiary structure of a protein as a result of alteration in the environment pH, temperature, ionic strength) or the binding of a ligand (to a receptor) or binding of substrate (to an enzyme). (18 Nov 1997) |
| Crooke's hyaline change | Replacement of cytoplasmic granules of basophil cells of the anterior pituitary by homogenous hyaline material; a characteristic finding in Cushing's syndrome, but usually not present in the cells of a basophil adenoma. Synonym: Crooke's hyaline degeneration. (05 Mar 2000) |
| social change | Social process whereby the values, attitudes, or institutions of society, such as education, family, religion, and industry become modified. It includes both the natural process and action programs initiated by members of the community. (12 Dec 1998) |
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