| PHA | passive hemagglutination [test]; peripheral hyperalimentation; phenylalanine; phytohemagglutinin; ph... |
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| PHA-1 | Pseudohypoaldosteronism type 1 |
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| pseudohypoaldosteronism | A hereditary disorder characterised by salt wasting and growth retardation, presenting in infancy as high levels of urinary sodium despite hyponatraemia, hyperkalaemia, hyperreninaemia, and elevated aldosterone levels. The mode of inheritance is probably autosomal dominant, affecting electrolyte secretion in the kidney tubule. (12 Dec 1998) |
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Synonyms : Pseudohypoaldosteronism, Type I, Autosomal Dominant, Pseudohypoaldosteronism, Type I, Autosomal Recessive, Pseudohypoaldosteronism, Type II, Pseudohypoaldosteronisms, Type II Pseudohypoaldosteronism
| pseudohypoaldosteronism |
1. a hereditary disorder of infancy characterized by severe salt and water depletion and other signs of aldosterone deficiency, even though normal or elevated amounts of aldosterone are secreted. Causes include aldosterone receptor defects and renal dysfunction. Some affected infants outgrow the need for dietary salt supplements in early childhood. 2. the endocrine abnormality associated with salt-losing nephropathy, usually that due to chronic pyelonephritis, seen primarily in adults. See also Gordon's syndrome, under syndrome.
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