| ¿µ¹® | serum proteins | ÇÑ±Û | Ç÷û´Ü¹é |
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| PBPs | Penicillin-Binding Proteins |
|---|---|
| PVM | pneumonia virus of mice; proteins, vitamins, and minerals |
| RPSP | reference preparation for serum proteins |
| G proteins | GIP-binding proteins |
|---|---|
| G-proteins | GTP)-binding regulatory proteins |
| G-proteins | Guanine nucleotide-binding regulatory proteins |
| G proteins | reglatory proteins |
| APP | Acute phase proteins |
| proto-oncogene proteins | Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity. (12 Dec 1998) |
|---|---|
| proto-oncogene proteins c-abl | Membrane proteins encoded by the c-abl genes. They exhibit tyrosine kinase activity and play a role in normal haematopoiesis especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific n-terminal amino acids are deleted, releasing the kinase from negative regulation. (12 Dec 1998) |
| proto-oncogene proteins c-bcl-2 | Membrane proteins encoded by the bcl-2 genes and serving as a potent inhibitor of cell death by apoptosis. The proteins are found on mitochondrial, microsomal, and nuclear membrane sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma. (12 Dec 1998) |
| proto-oncogene proteins c-erbb-2 | Cellular proteins in the epidermal growth factor receptor family encoded by the c-erbb genes. These proteins are overexpressed in a significant portion of adenocarcinomas found at various sites, especially in the breast. Gene amplification appears to be the predominant method leading to overexpression. (12 Dec 1998) |
| proto-oncogene proteins c-fos | Cellular DNA-binding proteins encoded by the c-fos genes (genes, fos). They are involved in growth-related transcriptional control. C-fos combines with c-jun (proto-oncogene proteins c-jun) to form a c-fos/c-jun heterodimer (transcription factor ap-1) that binds to the tre (tpa-responsive element) in promoters of certain genes. (12 Dec 1998) |
| proto-oncogene proteins c-jun | Cellular DNA-binding proteins encoded by the c-jun genes (genes, jun). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun. (12 Dec 1998) |
| proto-oncogene proteins c-kit | Tyrosine kinase membrane receptors which are the natural ligands for mast cell growth factor (steel factor). This interaction is crucial for the development of haematopoietic, gonadal, and pigment stem cells. (12 Dec 1998) |
| proto-oncogene proteins c-met | <enzyme> A transmembrane tyrosine kinase that is the receptor for hepatocyte growth factor (scatter factor). It consists of an extracellular alpha chain which is disulfide linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and critical sites for the regulation of kinase activity. Registry number: EC 2.7.11.- (12 Dec 1998) |
| proto-oncogene proteins c-mos | Cellular proteins encoded by the c-mos genes (genes, mos). They function in the cell cycle to maintain maturation-promoting factor in the active state and have protein-serine/threonine kinase activity. Oncogenic transformation can take place when c-mos proteins are expressed at the wrong time. (12 Dec 1998) |
| proto-oncogene proteins c-myc | Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumourigenesis. (12 Dec 1998) |
| proto-oncogene proteins c-raf | <enzyme> A class of serine-threonine kinases involved in cellular signal transduction. Included in this class are the proto-oncogene proteins mil and raf. Raf is a component of a signal transduction pathway leading to increased gene expression through the c-jun DNA binding site, ap1. Registry number: EC 2.7.10.- (12 Dec 1998) |
| adenovirus e1a proteins | Proteins transcribed from the e1a region of adenovirus which are involved in positive regulation of transcription of the early genes. (12 Dec 1998) |
|---|---|
| adenovirus e1b proteins | Proteins transcribed from the e1b region of adenovirus which are involved in regulation of the levels of early and late gene expression. (12 Dec 1998) |
| adenovirus e1 proteins | The very first viral gene products synthesised after cells are infected with adenovirus. The e1 region of the genome has been divided into two major transcriptional units, e1a and e1b, each expressing proteins of the same name (adenovirus e1a proteins and adenovirus e1b proteins). (12 Dec 1998) |
| adenovirus e2 proteins | Proteins transcribed from the e2 region of adenovirus. Several of these are required for viral DNA replication. (12 Dec 1998) |
| adenovirus e3 proteins | Proteins transcribed from the e3 region of adenovirus but not essential for viral replication. The e3 19k protein mediates adenovirus persistence by reducing the expression of class I major histocompatibility complex antigens on the surface of infected cells. (12 Dec 1998) |
| adenovirus e4 proteins | Proteins transcribed from the e4 region of adenovirus. The e4 19k protein transactivates transcription of the adenovirus e2f protein and complexes with it. (12 Dec 1998) |
| adenovirus early proteins | <molecular biology, protein, virology> Proteins encoded by adenoviruses that are synthesised prior to, and in the absence of, viral DNA replication. The proteins are involved in both positive and negative regulation of expression in viral and cellular genes, and also affect the stability of viral mRNA. Some are also involved in oncogenic transformation. (12 Dec 1998) |
| amino acids, peptides, and proteins | Amino acids and chains of amino acids connected by peptide linkages. (12 Dec 1998) |
| androgen-binding proteins | Carrier proteins produced in the sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. Participate in the transport of androgens; include also synthetic androgens binding proteins. (12 Dec 1998) |
| archaeal proteins | Proteins found in any species of archaeon. (12 Dec 1998) |
| bacterial outer membrane proteins | Proteins isolated from the outer membrane of bacteria. (12 Dec 1998) |
| bacterial proteins | Proteins found in any species of bacterium. (12 Dec 1998) |
| basic proteins | Proteins that are rich in basic amino acids; e.g., histones. (05 Mar 2000) |
| Bence Jones proteins | Proteins with unusual thermosolubility found in the urine of patients with multiple myeloma, consisting of monoclonal immunoglobulin light chains. See: Bence Jones reaction. See: immunoglobulin. (05 Mar 2000) |
| blood proteins | The hundreds of different proteins present in blood plasma, including carrier proteins (such as serum albumin, transferrin, and haptoglobins), fibrinogen and other blood coagulation factors, complement components, immunoglobulins, enzyme inhibitors, precursors of substances such as the angiotensins and bradykinin, and many other types of proteins. (12 Dec 1998) |
Synonyms : Proto Oncogene Proteins, Cellular, Proto-Oncogene Products, Cellular, Cellular Proto Oncogene Proteins, Cellular Proto-Oncogene Products, Proto Oncogene Products, Cellular, Proto Oncogene Proteins, Proto-Oncogene Proteins, Cellular, c onc Proteins
Synonyms : A-raf Kinase, A-raf Protein Kinase, A-raf-1 Protein, Proto-Oncogene Protein A-raf, A raf 1 Protein, A raf Kinase, A raf Protein Kinase, Kinase, A-raf, Kinase, A-raf Protein, Proteins A-raf, Proto-Oncogene, Proto Oncogene Protein A raf
Synonyms : B-raf Kinases, BRAF Kinases, Proto-Oncogene Protein B-raf, B raf Kinases, B-raf, Proto-Oncogene Protein, B-raf, Proto-Oncogene Proteins, Protein B-raf, Proto-Oncogene, Proteins B-raf, Proto-Oncogene, Proto Oncogene Protein B raf, Proto Oncogene Proteins B raf
Synonyms : Proto-Oncogene Proteins abl, abl Proto-Oncogene Products, Products, abl Proto-Oncogene, Proteins abl, Proto-Oncogene, Proto Oncogene Proteins abl, Proto Oncogene Proteins c abl, Proto-Oncogene Products, abl, Proto-Oncogene Proteins, abl, c abl Proteins
Synonyms : AKT1 Protein Kinase, AKT2 Protein Kinase, AKT3 Protein Kinase, Akt-alpha Protein, Akt-beta Protein, Akt-gamma Protein, Protein Kinase B, Protein Kinase B alpha, Protein Kinase B beta, Protein Kinase B gamma, Protein-Serine-Threonine Kinase (Rac), RAC-PK Protein
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