| ¿µ¹® | inguinal region of abdomen | ÇÑ±Û | »ô, ¼ÇýºÎ, »ô°í¶û |
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| PAR | participating provider; passive avoidance reaction; perennial allergic rhinitis; photosynthetically ... |
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| DABP | D site albumin promoter binding protein |
| ESP | early systolic paradox; echo spacing; effective sensory projection; effective systolic pressure; end... |
| GPE | guinea pig embryo; granulocyte colony-stimulating factor promoter element |
| GPEBP | granulocyte colony-stimulating factor promoter element binding protein |
| AdMLP | Adenovirus major late promoter |
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| Ad2MLP | Adenovirus-2 major late promoter |
| COUP-TF | Chicken Ovalbumin Upstream Promoter Transcription Factor |
| COUP-TFII | Chicken ovalbumin upstream promoter transcription factor II |
| IPF-1 | Insulin promoter factor 1 |
stress-bearing region
| promoter regions | <genetics> DNA sequences which are recognised (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the pribnow box in bacteria and the tata box in eukaryotes. (12 Dec 1998) |
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| constituative promoter | An unregulated promoter that allows for continual transcription of itsassociated gene. (09 Oct 1997) |
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| promoter | <molecular biology> A region of DNA to which RNA polymerase binds before initiating the transcription of DNA into RNA. The nucleotide at which transcription starts is designated +1 and nucleotides are numbered from this with negative numbers indicating upstream nucleotides and positive downstream nucleotides. most bacterial promoters contain two consensus sequences that seem to be essential for the binding of the polymerase. The first, the Pribnow box, is at about 10 and has the consensus sequence 5' TATAAT 3'. The second, the 35 sequence, is centred about 35 and has the consensus sequence 5' TTGACA 3'. most factors that regulate gene transcription do so by binding at or near the promoter and affecting the initiation of transcription. Much less is known about eukaryote promoters, each of the three RNA polymerases has a different promoter. RNA polymerase I recognises a single promoter for the precursor of rRNA. RNA polymerase II, that transcribes all genes coding for polypeptides, recognises many thousands of promoters. most have the Goldberg Hogness or TATA box that is centred around position 25 and has the consensus sequence 5' TATAAAA 3'. Several promoters have a CAAT box around 90 with the consensus sequence 5' GGCCAATCT 3'. There is increasing evidence that all promoters for housekeeping genes contain multiple copies of a GC rich element that includes the sequence 5' GGGCGG 3'. Transcription by polymerase II is also affected by more distant elements known as enhancers. RNA polymerase III synthesises 5s ribosomal RNA, all tRNAs and a number of small RNAs. The promoter for RNA polymerase III is located within the gene either as a single sequence, as in the 5s RNA gene or as two blocks, as in all tRNA genes. (13 Nov 1997) |
| promoter insertion | <molecular biology> Activation of a gene by the nearby integration of a virus. The long-terminal repeat acts as a promoter for the host gene. A form of insertional mutagenesis. (18 Nov 1997) |
| down promoter mutation | <molecular biology> A mutation (a change in base pair sequence) in a promoter region, this results in lower gene expression (less transcription of the gene occurs). (09 Oct 1997) |
| tumour promoter | <molecular biology, oncology> Agent that in classical studies of carcinogenesis in rodent skin was able to increase the sensitivity of tumour formation by a previously applied primary carcinogen, but was unable to induce tumours when used alone. Important example was croton oil, active ingredients of which are now believed to be phorbol esters. These are believed to act as analogues of diacylglycerols and may activate protein kinase C. Strictly speaking, not the same as a co carcinogen, which is defined as being active when administered at the same time. Tumour promoters generally are carcinogens when tested more stringently. (18 Nov 1997) |
| up promoter mutation | A mutation that increases the frequency of initiation of transcription. (05 Mar 2000) |
| anal region | The posterior portion of the perineal region through which the anal canal opens; bounded by a line through both isehial tuberosities, the sacrotuberous ligaments and the coccyx. Synonym: regio analis, anal region. (05 Mar 2000) |
| ankle region | The region of the lower limb between the leg (crus) and the foot (pes). Synonym: regio talocruralis. (05 Mar 2000) |
| anterior antebrachial region | The area between the radial and ulnar borders of the forearm anteriorly. Synonym: facies antebrachialis anterior, regio antebrachialis anterior, anterior antebrachial region, anterior surface of forearm, facies anterior antebrachii. (05 Mar 2000) |
| anterior brachial region | The anterior region of the arm. (05 Mar 2000) |
| anterior carpal region | The anterior part of the wrist. Synonym: regio carpalis anterior. (05 Mar 2000) |
| anterior crural region | The anterior surface of the inferior limb between the knee and the ankle. Synonym: facies cruralis anterior, regio cruralis anterior, anterior crural region, anterior surface of leg, facies anterior cruris. (05 Mar 2000) |
| anterior cubital region | The area in front of the elbow, including the cubital fossa. Synonym: facies cubitalis anterior, regio cubitalis anterior, anterior cubital region, anterior surface of elbow. (05 Mar 2000) |
| anterior hypothalamic region | The rostral portion of the hypothalamus that includes preoptic, supraoptic, paraventricular and anterior hypothalamic nuclei; the hypothalamic structures located internally in the general area of the optic chiasm. (05 Mar 2000) |
| anterior knee region | The anterior region of the knee. Synonym: regio genus anterior. (05 Mar 2000) |
Synonyms : Promoter, Promoter Regions, Promotor, Promotor (Genetics), Promotor Regions, Promotor Regions (Genetics), Pseudopromoter, Early Promoter, Late Promoter, Middle Promoter, Promoter Region, Promoter Region (Genetics), Promoter, Early, Promoter, Late, Promoter, Middle
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