| proerythroblast | The earliest of four stages in development of the normoblast. See: erythroblast. Synonym: lymphoid haemoblast of Pappenheim, proerythroblast, rubriblast. (05 Mar 2000) |
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| proerythroblast |
the earliest of the immature forms recognizable as a precursor of the mature erythrocyte. It is round, with a large nucleus occupying most of the cell and surrounded by a small amount of cytoplasm that is a clear deep blue, often stains unevenly, and shows a pale perinuclear halo. The nucleus is round and reddish-purple with several nucleoli and consists of a network of fairly uniformly distributed chromatin strands that give it a finely reticular appearance. This term may be used to refer to cells in either normal or abnormal maturation, but some authorities limit it to those involved in normal maturation, in contrast to promegaloblasts, in which case it is a synonym of pronormoblast. Called also rubriblast.
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