| ADEPT | Antibody Directed Enzyme Prodrug Therapy |
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| GDEPT | Gene directed enzyme prodrug therapy |
| prodrug | A compound that is converted within the body into its active form that has medical effects. Prodrugs useful when the active drug may be too toxic to administer ter systemically, the active drug is absorbed poorly by the digestive tract, or the body breaks down the active drug before it reaches its target. (09 Oct 1997) |
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| prodrugs | A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. (12 Dec 1998) |
| Antibody Directed Enzyme Prodrug Therapy | <pharmacology> A method for targeting a drug to a specific tissue, in which the targeting agent and the drug are administered separately. The drug is designed to be inactive (a prodrug) until it is converted by an enzyme, which is the targeting agent. The enzyme is coupled to an antibody that directs it to the tissue of interest. When the enzyme arrives at the tissue, the prodrug is activated only at that site, sparing other tissues from potentially toxic side effects. Acronym: ADEPT (14 Nov 1997) |
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Synonyms : Pro-Drugs, Precursors, Drug, Pro Drugs
| prodrug |
An inactive drug precursor that is activated by a biological process, such as enzymatic cleavage.
Ãâó: www.genpromag.com/Glossary~LETTER~P.html
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| prodrug |
A compound that the body converts into active drug.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
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| prodrug |
an inactive form of a drug that exerts its effects after metabolic processes within the body convert it to a usable or active form.
Ãâó: www.thebody.com/sfaf/summer01/glossary.html
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| prodrug |
A chemical structure that undergoes conversion to an active drug within a biological system, such conversion usually involving metabolism.
Ãâó: www.exchemistry.com/glossary.html
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