| PBGS, PBG-S | porphobilinogen synthase |
|---|---|
| PBG | porphobilinogen |
| PBGD | porphobilinogen deaminase |
| PGB | porphobilinogen; prostaglandin B |
| ALAS | delta-aminolevulinate synthase |
| PBGS | Porphobilinogen synthase |
|---|---|
| PBG | Porphobilinogen |
| PBGD | Porphobilinogen Deaminase |
| NO Synthase | nitric oxide synthase |
| iNOS | 1.Inducible NO synthase |
| porphobilinogen synthase | <enzyme> An enzyme that catalyses the formation of porphobilinogen from two molecules of 5-aminolevulinic acid. Chemical name: 5-Aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing) Registry number: EC 4.2.1.24 (12 Dec 1998) |
|---|---|
| porphobilinogen synthase porphyria | An inherited disorder in which there is a deficiency of porphobilinogen synthase; d-aminolevulinate levels are elevated, leading to neurological disturbances. Synonym: porphobilinogen synthase porphyria. (05 Mar 2000) |
| porphobilinogen | <chemical> Chemical name: 1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)- (12 Dec 1998) |
|---|---|
| porphobilinogen oxygenase | <enzyme> Porphobilinogen is converted to 5-oxo-porphobilinogen Registry number: EC 1.13.- (26 Jun 1999) |
| abequose synthase | <enzyme> Converts cdp-4-keto-3,6-dideoxy-d-glucose to cdp-3,6-dideoxy-d-galactose (cdp-abequose); requires NADPH, analogous to udp-glucose-4-epimerase Registry number: EC 5.1.3.- Synonym: rfbj gene product (26 Jun 1999) |
| acetoacetyl-acyl carrier protein synthase | <enzyme> E coli enzyme, that catalyses condensation of malonyl-acyl carrier protein plus acetyl-acyl carrier protein; not inhibited by cerulenin Registry number: EC 2.3.1.- Synonym: acetoacetyl-acp synthase (26 Jun 1999) |
| acetolactate synthase | <enzyme> A flavoprotein that catalyses the formation of acetolactate from 2 moles of pyruvate in the biosynthesis of valine and the formation of acetohydroxybutyrate from pyruvate and alpha-ketobutyrate in the biosynthesis of isoleucine. Chemical name: Acetolactate pyruvate-lyase (carboxylating) Registry number: EC 4.1.3.18 (12 Dec 1998) |
| acridone synthase | <enzyme> Catalyses the condensation of n-methylanthraniloyl-CoA and 3 malonyl-CoA to produce 1,3-dihydroxy-n-methylacridone Registry number: EC 2.3.1.- (26 Jun 1999) |
| acyl-malonyl-ACP synthase | <enzyme> An enzyme condensing malonyl-ACP and acyl-cys-protein to 3-oxoacyl-ACP + cys-protein + CO2, and similar reactions, as steps in fatty acid synthesis; cys-protein is also a part of the fatty acid synthase complex. Synonym: acyl-malonyl-ACP synthase, beta-ketoacyl-ACP synthase. (05 Mar 2000) |
| adenylosuccinate synthase | <enzyme> A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyses the synthesis of adenylosuccinate from GTP, imp, and aspartate with the formation of orthophosphate and GDP. Chemical name: IMP:L-aspartate ligase (GDP-forming) Registry number: EC 6.3.4.4 (12 Dec 1998) |
| adenylylosuccinate synthase | <enzyme> A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyses the synthesis of adenylosuccinate from GTP, imp, and aspartate with the formation of orthophosphate and GDP. Chemical name: IMP:L-aspartate ligase (GDP-forming) Registry number: EC 6.3.4.4 (12 Dec 1998) |
| agropine synthase | <enzyme> Final enzyme in the three enzyme pathway for agropine synthesis; cyclises deoxymannityl-glutamine to the lactone, agropine Registry number: EC 4.2.1.- Synonym: ags gene product (26 Jun 1999) |
| alkylglycerone-phosphate synthase | <enzyme> Replaces the acyl moiety of acyldhap with a long chain fatty alcohol; intact alcohol including the oxygen atom is incorporated into alkyl-dhap Registry number: EC 2.5.1.26 Synonym: adhps, alkyl-dihydroxyacetone phosphate synthase, alkyl-dhap synthase, alkyldihydroxyacetone phosphate synthetase, acylglycerone-3-phosphate-long chain-alcohol o-3-phospho-2-oxopropanyl transferase, alkyldihydroxyacetonephosphate synthase (26 Jun 1999) |
| aminoadipic d-saemialdehyde synthase | <enzyme> A bifunctional enzyme used in lysine degradation; it has a lysine:alpha-ketoglutarate reductase activity as well as a saccharopine dehydrogenase activity. A deficiency of this enzyme results in familial hyperlysinaemia. (05 Mar 2000) |
| aminoadipic saemialdehyde synthase | <enzyme> Bifunctional enzyme with both lysine-ketoglutarate reductase (EC 1.5.1.8) and saccharopine dehydrogenase (EC 1.5.1.9) activities Registry number: EC 1.5.1.- Synonym: aasa synthase (26 Jun 1999) |
| aminodeoxychorismate synthase | <enzyme> From E coli; probably catalyses the conversion of chorismate to 4-amino-4-deoxychorismate; see also paba protein Registry number: EC 2.6.1.- Synonym: pabb gene product, adc synthase (26 Jun 1999) |
| amylopectin synthase | <enzyme> From eimeria tenella; catalyses udpglucose alpha 1,4-glucan alpha-4-glucosyltransferase forming amylopectin, similar to glycogen synthase in eukaryotes Registry number: EC 2.4.1.- (26 Jun 1999) |
Synonyms : ALA-Dehydrase, delta-Aminolevulinate Dehydratase, delta-Aminolevulinic Acid Dehydratase, ALA Dehydrase, Acid Dehydratase, Aminolevulinic, Acid Dehydratase, delta-Aminolevulinic, Aminolevulinate Hydro Lyase, Dehydratase, Aminolevulinic Acid
| porphobilinogen synthase |
[EC 4.2.1.24] an enzyme of the lyase class that catalyzes the condensation of two molecules of δ-aminolevulinate to form porphobilinogen in the synthesis of porphyrins. The enzyme is inhibited by minute quantities of lead poisoning. Genetic deficiency of the enzyme causes a porphyria similar to acute intermittent porphyria but with high urinary levels of δ-aminolevulinic acid, coproporphyrinogen III, and protoporphyrin but not porphobilinogen. Called also aminolevulinate dehydratase.
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