| ¿µ¹® | drug resistance | ÇÑ±Û | ¾à¹°³»¼º |
|---|---|---|---|
| ¼³¸í | 1. ÈÇпä¹ýÁ¦³ª Ç×»ý¹°ÁúÀÇ ¾î¶² ÀÏÁ¤ ³óµµ·Î ¼¼±ÕÀ» Á×À̰ųª Áõ½ÄÀúÇØ¸¦ ¹Þ´Â °ÍÀ» ÀÌ ÈÇпä¹ýÁ¦³ª Ç×»ý¹°Áú¿¡ °¨¼ö¼ºÀÌ ÀÖ´Ù°í Çϴµ¥, ÀÌ °¨¼ö¼ºÀÌ ¾ø°Ô µÈ »ýŸ¦ ÀúÇ×¼ºÀ̶óµç°¡ ³»¼ºÀ̶ó°í ¸»ÇÑ´Ù. µû¶ó¼ º¯À̹̻ý¹°ÀÇ ¾àÁ¦¿¡ ´ëÇÑ ÀÚÇ×¼ºÀ̶óµç°¡ ³»¼ºÀ̶ó°í ¸»ÇÑ´Ù. 2. ÀǾàǰÀ» °è¼Ó º¹¿ëÇϸé Á¡Â÷ Áõ·®ÇÏÁö ¾ÊÀ¸¸é È¿·ÂÀÌ ³ªÅ¸³ªÁö ¾Ê´Â ¼ºÁú. ÀÌ·¯ÇÑ ¶§¸¦ ¾àÁ¦³»¼ºÀÌ »ý°å´Ù°í ÇÑ´Ù. ¸ðµç ¹Ì»ý¹°Àº °¨¼ö¼ºÀ» °¡Áö´Â ¾à¹°¿¡ ÀÇÇÏ¿© »ç¸êµÇÁö¸¸, ¼Ò¼öÀÇ °ÍÀº »ì¾Æ³²¾Æ ±×°ÍÀÌ ÁøÈµÊÀ¸·Î½á »ç¸êÇÏÁö ¾Ê´Â ¼ö°¡ ÀÖ´Ù. ¶Ç, ÃÖÃÊ¿¡´Â °¨¼ö¼ºÀ» °¡Áö°í ÀÖ´ø ±ÕÀÌ Â÷Â÷ ³»¼º±ÕÀ¸·Î µÇ±âµµ ÇÑ´Ù. ¸¹Àº º´¿ø±ÕÀº °¨¼ö¼ºÀÌ ÀÖ´Â ÀǾàǰ¿¡ ´ëÇÏ¿© ³»¼ºÀÌ »ý±ä´Ù. °¡Àå °íµµÀÇ ³»¼º±ÕÀÌ »ý±â±â ½¬¿î °ÍÀº ½ºÆ®·¾Å丶À̽ÅÀε¥ °áÇÙ±Õ°ú ±×¶÷À½¼º±Õ¿¡ ´ëÇÏ¿© ½±°Ô ³»¼ºÀÌ »ý±ä´Ù. Æä´Ï½Ç¸°À̳ª Åׯ®¶ó½ÃŬ¸°(¾ÆÅ©·Î¸¶À̽Å) µîÀÇ Ç×»ý¹°Áúµµ ³»¼ºÀÌ »ý±â±â ½¬¿ì¹Ç·Î, »ç¿ëÇÒ ¶§´Â ÀûÀÀÀ» Àß È®ÀÎÇÏ¿© Çʿ䷮À» Á¤ÇÏ°í ¿¬¿ëÀ» ÇÇÇÑ´Ù. °°Àº È¿°ú°¡ ÀÖ´Â ´Ù¸¥ Á¾·ùÀÇ ¾àÁ¦¸¦ ¼Ò·®¾¿ 2, 3Á¾ º´¿ëÇÏ¸é ³»¼ºÀÇ ¹ß»ýÀÌ Å©°Ô ¾ïÁ¦µÈ´Ù´Â °ÍÀÌ ¾Ë·ÁÁ® ÀÖ´Ù. °áÇÙ¾àÀ¸·Î¼ ½ºÆ®·¾Å丶À̽Űú ÆÄ½º, ¶Ç´Â À̼ҴϾÆÁöµå¸¦ º´¿ëÇÏ´Â °Í µîÀÌ ±× ¿¹ÀÌ´Ù. |
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| ¿µ¹® | resistance | ÇÑ±Û | ³»¼º, ÀúÇ×¼º |
|---|---|---|---|
| ¼³¸í | ¨ç ¾à¹°ÀÇ ¹Ýº¹ º¹¿ë¿¡ ÀÇÇØ ¾àÈ¿°¡ ÀúÇÏÇÏ´Â Çö»ó. ¨è ¼¼±Õ µûÀ§ÀÇ º´¿øÃ¼°¡ ÈÇÐ ¿ä¹ýÁ¦³ª Ç×»ý ¹°ÁúÀÇ °è¼Ó »ç¿ë¿¡ ´ëÇÏ¿© ³ªÅ¸³»´Â ÀúÇ×¼º. ¼¼±ÕÀÇ ³»¼ºÈ¹µæÀÇ ¸ÞÄ¿´ÏÁò¿¡ ´ëÇØ¼´Â ¼¼Æ÷ÀÇ ±¸Á¶(¸®Æ÷Á», ¼¼Æ÷¸·) º¯È, ´ë»ç°èÀÇ º¯È, µ¹¿¬º¯ÀÌ µî¿¡ ÀÇÇÑ ¾à¹°°¨¼ö¼º ÀúÇÏ µîÀÌ ÃßÃøµÇ°í ÀÖ´Ù. ÇÑÆí ´Ù¸¥ ¾à¹°¿¡µµ ³»¼ºÀ» ³ªÅ¸³»´Â ±³Â÷³»¼º°ú, ¿©·¯ Á¾·ùÀÇ ¾à¹°¿¡ µ¿½Ã¿¡ ³»¼ºÀ» ȹµæÇÑ »óŸ¦ ´ÙÁ¦ ³»¼ºÀ̶ó°í ÇÑ´Ù. 3. ȯ°æ Á¶°ÇÀÇ º¯È¿¡ °ßµô ¼ö ÀÖ´Â »ý¹°ÀÇ ¼ºÁú. ³»¿¼º, ³»ÇѼº µûÀ§°¡ ÀÖ´Ù. |
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| ¿µ¹® | resistance | ÇÑ±Û | ÀúÇ× |
|---|---|---|---|
| ¼³¸í | ¨ç¾à¹°ÀÇ ¹Ýº¹ º¹¿ë¿¡ ÀÇÇØ ¾àÈ¿°¡ ÀúÇÏÇÏ´Â Çö»ó. ¨è ¼¼±Õ µûÀ§ÀÇ º´¿øÃ¼°¡ ÈÇÐ ¿ä¹ýÁ¦³ª Ç×»ý ¹°ÁúÀÇ °è¼Ó »ç¿ë¿¡ ´ëÇÏ¿© ³ªÅ¸³»´Â ÀúÇ×¼º. ¼¼±ÕÀÇ ³»¼ºÈ¹µæÀÇ ¸ÞÄ¿´ÏÁò¿¡ ´ëÇØ¼´Â ¼¼Æ÷ÀÇ ±¸Á¶(¸®Æ÷Á», ¼¼Æ÷¸·) º¯È, ´ë»ç°èÀÇ º¯È, µ¹¿¬º¯ÀÌ µî¿¡ ÀÇÇÑ ¾à¹°°¨¼ö¼º ÀúÇÏ µîÀÌ ÃßÃøµÇ°í ÀÖ´Ù. ÇÑÆí ´Ù¸¥ ¾à¹°¿¡µµ ³»¼ºÀ» ³ªÅ¸³»´Â ±³Â÷³»¼º°ú, ¿©·¯ Á¾·ùÀÇ ¾à¹°¿¡ µ¿½Ã¿¡ ³»¼ºÀ» ȹµæÇÑ »óŸ¦ ´ÙÁ¦ ³»¼ºÀ̶ó°í ÇÑ´Ù. ¨é ȯ°æ Á¶°ÇÀÇ º¯È¿¡ °ßµô ¼ö ÀÖ´Â »ý¹°ÀÇ ¼ºÁú. ³»¿¼º, ³»ÇѼº µûÀ§°¡ ÀÖ´Ù. |
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| ¿µ¹® | antihypertensive drug | ÇÑ±Û | °íÇ÷¾Ð¾à, Ç×°íÇ÷¾ÐÁ¦ |
|---|---|---|---|
| ¼³¸í | °íÇ÷¾ÐÀÇ Ä¡·á¿¡ »ç¿ëÇÏ¸ç ³ôÀº Ç÷¾ÐÀ» ³·Ãß´Â ¾à¹°À» ¸»ÇÑ´Ù. °íÇ÷¾Ð¾à¿¡´Â Ç÷°üÆòȰ±Ù¿¡ Á÷Á¢ ÀÛ¿ëÇÏ¿© À̿ϽÃŰ´Â Ç÷°üÈ®ÀåÁ¦(È÷µå¶ó¶óÁø), ±³°¨½Å°æÀÇ È°µ¿À» ¾îµð¼±°¡ Â÷´ÜÇÏ´Â ¾à¹°(·¹¼¼¸£ÇÉ, ¸ÞÆ¿µµÆÄ, ÇÁ·ÎÇÁ¶ó³ë·Ñ), ÀÌ´¢Á¦(ÇÁ·Î¼¼¹Ìµå, ¿¡Å¸Å©¸°»ê)ÀÌ »ç¿ëµÈ´Ù. |
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| ¿µ¹® | antimalarial drug | ÇÑ±Û | ¸»¶ó¸®¾Æ¾à, Ç׸»¶ó¸®¾ÆÁ¦ |
|---|---|---|---|
| ¼³¸í | ¸»¶ó¸®¾Æ Ä¡·á¿¡ ¾²´Â ¾à. Ű´Ï³×, Ŭ·Î·ÎÄý, ÇÁ¸®¸¶Äý µûÀ§°¡ ÀÖ´Ù. ¸»¶ó¸®¾Æ ¿øÃæÀÇ ¹ßÀ°Áֱ⿡ ´ëÀÀÇØ¼ ¾à¹°ÀÌ ÀÖÀ¸³ª ´ëºÎºÐÀº º´¿ë¿ä¹ý¿¡ µû¶ó¼ ¸»¶ó¸®¾Æ Ä¡·á¸¦ ÇÑ´Ù. ¸ð±â¿¡ ÀÇÇÑ Æ÷ÀÚü°¨¿°¿¡ ´ëÇÑ Çׯ÷ÀÚü ¾àÀº µ¶¼º µîÀÇ ¹®Á¦°¡ ÀÖ¾î¼ ¾ÆÁ÷ ¾ø´Ù. ÀûÇ÷±¸³»¿¡¼ÀÇ È¯»óü, ¹ø½Äü¿¡¸¸ ÀÛ¿ëÇÏ´Â °Í(Ç×¹ø½Äü ¾àÀº Ŭ·Î·ÎÄý, ÇǸ®¸ÞŸ¹Î, Ŭ·Î·Î±¸¾Æ³ªÀ̵å, Ű´Ï³×)Àº ÀûÇ÷±¸ ¿ÜÀÇ ¹ßÀ°Àº ¾ïÁ¦ÇÏÁö ¾ÊÀ¸¹Ç·Î °¨¿°À» ¿ÏÀüÈ÷ ÀúÁöµÇÁö ¾Ê´Â´Ù. ÀûÇ÷±¸³»¿ÜÀÇ ¿øÃæ¿¡ ÀÛ¿ëÇØ ¿ÏÀüÈ÷ °¨¿°À» ¾ïÁ¦ÇÏ´Â °Í(ÆÄ¸¶Å², ÆæÅ¸Å², ÇÁ¸®¸¶Å²), Ç÷ÁßÀÇ »ý½Äü¸¦ Á×ÀÌ´Â °Í(´ëºÎºÐÀÇ Ç׸»¶ó¸®¾ÆÁ¦)Àº ¸ð±â¿¡ ÀÇÇÑ Å¸ÀÎÀ¸·ÎÀÇ Àü¿°¿øÀº ²÷±â´Âµ¥ ȯÀÚÀÚ½ÅÀÇ Áõ»óÀº º¯ÈÇÏÁö ¾Ê´Â´Ù. |
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| IR | drop of voltage across a resistor produced by a current; ileal resection; immune response; immunizat... |
|---|---|
| ER | efficiency ratio; epigastric region; ejection rate; electroresection; emergency room; endoplasmic re... |
| SR | sarcoplasmic reticulum; saturation recovery; scanning radiometer; screen; secretion rate; sedimentat... |
| DA | dark adaptation; dark agouti [rat]; daunomycin; degenerative arthritis; delayed action; Dental Assis... |
| JVP | [POMD P 49 - 52] 1) Jugular Vein Pressure 2) Jugular Venous Pulse ... |
| MDR | Multi drug resistance |
|---|---|
| MDR | Multiple Drug Resistance |
| MDR-1 | multi-drug resistance gene-1 |
| APC resistance | Resistance to activated protein C |
| ADAP | AIDS Drug Assistance Program |
| pleiotropic | Having multiple effects. For example: the cyclic AMP concentration in a cell will have a variety of effects because the cAMP acts to control a protein kinase that in turn affects a variety of proteins. (18 Nov 1997) |
|---|---|
| pleiotropic gene | A gene that has multiple, apparently unrelated, phenotypic manifestations. Synonym: polyphenic gene. (05 Mar 2000) |
| drug resistance | The ability of bacteria and other microorganisms to withstand a drug to which they were once sensitive (and were once stalled or killed outright). (12 Dec 1998) |
| drug resistance, microbial | The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through plasmids containing resistance factors (r factors). (12 Dec 1998) |
| drug resistance, multiple | Simultaneous resistance to a broad spectrum of structurally and functionally distinct drugs following exposure to a single agent. It is thought to result from the overexpression of genes encoding an integral plasma membrane protein, p-glycoprotein. (12 Dec 1998) |
| drug resistance, neoplasm | Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures. (12 Dec 1998) |
| drug-drug interaction | The effects that occur when two or more drugs are used together. Such effects include changes of absorption in the digestive tract, changes in rate of the drugs' breakdown in the liver, new or enhanced side effects and changes in the drugs' activity. (09 Oct 1997) |
| airway resistance | The opposition of the tracheobronchial tree to air flow: the mouth-to-alveoli pressure difference divided by the air flow. (12 Dec 1998) |
| ampicillin resistance | Nonsusceptibility of a microbe to the action of ampicillin, a penicillin derivative that interferes with cell wall synthesis. (12 Dec 1998) |
| androgen resistance syndromes | A class of disorders associated with 5a-steroid reductase deficiency, testicular feminization, and related disorders. Compare: steroid 5a-reductase, Reifenstein's syndrome, infertile male syndrome, testicular feminization syndrome. (05 Mar 2000) |
| antibiotic resistance | The ability of a bacterium tosynthesise a protein that neutralises an antibiotic. (09 Oct 1997) |
| antibiotic resistance gene | Genes in a microorganism which confer resistance to antibiotics, for example by coding for enzymes which destroy it, by coding for surface proteins which prevent it from entering the microorganism, or by being a mutant form of the antibiotic's target so that it can ignore it. (09 Oct 1997) |
| bacteriophage resistance | Resistance of a bacterial mutant to infection by a bacteriophage to which the parent (wild type) strain is susceptible. (05 Mar 2000) |
| beta-lactam resistance | Nonsusceptibility of an organism to the action of the beta-lactam antibiotics. (12 Dec 1998) |
| capillary resistance | The resistance offered to the flow of blood through the capillary portion of the peripheral vascular bed. (12 Dec 1998) |
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