| ¿µ¹® | platelet | ÇÑ±Û | Ç÷¼ÒÆÇ |
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| ¼³¸í | °ñ¼öÀÇ °Å´ë ¼¼Æ÷ÀÎ °Å´ëÇÙ¼¼Æ÷ÀÇ ¼¼Æ÷Áú ÀϺΰ¡ ¶³¾îÁ®¼ ¼øÈ¯ Ç÷¾× Áß¿¡ ÃâÇöÇÑ °ÍÀ¸·Î Á÷°æÀÌ 2~4¥ìmÀÇ ÀÛÀº °ú¸³Ã¼ÀÌ´Ù. Ç÷¼ÒÆÇÀº ¼Õ»óÀ» ÀÔÀº Ç÷°üÀÇ ³ëÃâµÈ °áÇÕ Á¶Á÷¿¡ ºÙ¾î ¿©·¯ ¹°ÁúÀ» ºÐºñÇÏ¿© ÁöÇ÷ ¹× Ç÷¾× ÀÀ°í¿¡ Áß¿äÇÑ ¿ªÇÒÀ» ÇÑ´Ù. |
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| ¿µ¹® | basement membrane | ÇÑ±Û | ¹Ù´Ú¸·, ±âÀú¸· |
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| ¼³¸í | »óÇǼ¼Æ÷, ±ÙÀ°¼¼Æ÷, ½Å°æÁ¶Á÷°ú ±×°ÍµéÀÇ ¹Ù±ùÂÊ °áÇÕÁ¶Á÷ÀÇ °æ°è¿¡ ÀÖ´Â Á¡¾×´Ù´çÁú°ú ´Ü¹éÁú·Î ±¸¼ºµÈ ¾ãÀº ¸·. ±âÃʸ· ¶Ç´Â °æ°è¸·À̶ó°íµµ ÇÑ´Ù. µÎ²²´Â 50~80nmÀÌ´Ù. ±âÀú¸·Àº 20~30nm °£°ÝÀ¸·Î ´Ã¾î¼± Á·¼¼Æ÷·Î µÈ »óÇǼ¼Æ÷ÀÇ 3ÃþÀ¸·Î µÇ¾î ÀÖ°í, ºÐÀÚ·® 40,000~60,000ÀÇ ¹°ÁúÀ» Åõ°úÇÒ ¼ö ÀÖ°Ô ÇÑ´Ù. ¶ÇÇÑ Ç¥ÇÇ¿Í ÁøÇÇÀÇ °æ°è·Î ¿µ¾çÀ» °ø±ÞÇÏ´Â ±âÁö ¿ªÇÒÀ» ÇÑ´Ù. ÁÖ·Î ¼¶À¯¸¦ Æ÷ÇÔÇÏ¿© ´Ù´ç·ù·Î µÇ¾î Àִµ¥, ÇöÀúÇÏ°Ô ¹ß´ÞµÇ¾î ÀÖ´Â ºÎºÐ°ú ±×·¸Áö ¾ÊÀº ºÎºÐÀÌ ÀÖ´Ù. ºñÁ¡¸·¿¡¼´Â Á¡¸·»óÇÇÀÇ ¹Ø¿¡ ¹ß´ÞÇÑ ±âÀú¸·ÀÌ ÀÖ´Ù. ÀÌ ¸· À§¿¡ û°¢¼ö¿ë¼¼Æ÷ÀÎ Åм¼Æ÷¸¦ °®´Â ÄÚ¸£Æ¼±â°üÀÌ Á¸ÀçÇÑ´Ù. ±âÀú¸·Àº ÀüÁ¦°¡ À½Àü±â ¼ºÁúÀ» °¡Áö°í ÀÖ¾î ¾çÀü±â¸¦ °¡Áø ¹°ÁúÀÌ Åõ°úÇϱ⠽±´Ù. ±âÀú¸·ÀÌ ÆØÈÇϰųª ¹Ðµµ°¡ ³·¾ÆÁö¸é ´Ü¹éÁúÀÌ Åë°úÇÏ¿© ´Ü¹é´¢¸¦ ÀÏÀ¸Å°°í, ±âÀú¸·¿¡ ±Õ¿-ÆÄ±« µîÀÌ ÀϾ¸é ÀûÇ÷±¸ µîÀÇ Ç÷¾× °íÇü¼ººÐÀÌ Åõ°úÇÏ¿© Ç÷´¢°¡ µÈ´Ù. |
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| ¿µ¹® | hyaline membrane disease | ÇÑ±Û | À¯¸®Áú¸·º´ |
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| ¼³¸í | ÇãÆÄ ¼º¼÷µµÀÇ ¹Ì¼÷À¸·Î ÇãÆÄ²Ê¸®¸¦ ÆØÃ¢½ÃŰ´Â ¹°Áú(Ç¥¸éȰ¼ºÁ¦)ÀÌ ºÎÁ·ÇÏ¿© È£Èí°ï¶õÀÌ ÃÊ·¡µÇ´Â º´À¸·Î¼ ¹Ì¼÷¾Æ¿¡ È£¹ßÇϴµ¥, Ãâ»ý½Ã ÀӽűⰣº¸´Ùµµ ÇãÆÄ ¼º¼÷ Á¤µµ°¡ ´õ °ü¿©µÈ´Ù. ´ÜÀÏ º´À¸·Î¼´Â »ç¸Á·üÀÌ °¡Àå ³ôÀ¸¸ç(¾à 30%), ½Å»ý¾ÆÀÇ ´ëÇ¥ÀûÀÎ º´ÀÌ´Ù. ÀÓ»óÀûÀ¸·Î´Â ¹Ì¼÷¾Æ, »ýÈÄ 6~8½Ã°£³» È£Èí°ï¶õÁõ¼¼ ÃâÇö°ú »ýÈÄ 24~48½Ã°£ÀÇ Áõ»ó ¾ÇÈ, »ýÈÄ 2~3Àϰ£ ÀΰøÀûÀ¸·Î »ê¼Ò¸¦ °ø±ÞÇÏÁö ¾ÊÀ¸¸é È£ÈíÀ» °è¼Ó½Ãų ¼ö°¡ ¾øÀ¸¸ç Á¡Á¡´õ »ê¼ÒÀÇ °ø±Þ ÀÇÁ¸µµ°¡ ³ô¾ÆÁö¸ç, µ¿¸ÆÇ÷¾×¼ÓÀÇ »ê¼Ò³óµµ°¡ ³»·Á°¡°í ÀÌ»êÈź¼ÒÀÇ ³óµµ°¡ ³ôÀ¸¸ç, ÈäºÎ ¹æ»ç¼± ¼Ò°ßÀ» ÂüÀÛÇÏ¿© Áø´ÜÇÑ´Ù. ȯ¾Æ´Â ¼÷·ÃµÈ °£È£ Àη°ú ÷´Ü ÀÇ·á Àåºñ°¡ ¼³Ä¡µÈ ½Å»ý¾Æ ÁýÁß Ä¡·á½Ç¿¡¼ Ä¡·áÇÏ¿©¾ß ÇÑ´Ù. ¿¹ÈÄ´Â Áõ¼¼ÀÇ °æÁß¿¡ µû¶ó ´Ù¸£°í »ç¸Á·üÀº 30~50% µÈ´Ù. ¾î¶² ¾Æ±â¿¡ À־ ġ·á ÈÄ¿¡ ´«À̳ª ±â°üÁöÇãÆÄ °èÅë¿¡ Àå¾Ö¸¦ ÀÏÀ¸Å°´Â »ê¼ÒÁßµ¶ÁõÀÌ º¸°íµÇ°í ÀÖ´Ù. |
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| ¿µ¹® | plasma membrane | ÇÑ±Û | ÇüÁú¸· |
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| ¼³¸í | ¿øÇüÁú Ç¥¸éÀ» µ¤´Â ¿¯Àº¸·. µÎ²²´Â 5~25¥ìmÀÌ´Ù. ±¤ÇÐÇö¹Ì°æÀ¸·Î´Â °üÂûÇÒ ¼ö ¾øÁö¸¸ ÀüÀÚÇö¹Ì°æÀ¸·Î °üÂûÀÌ °¡´ÉÇÏ´Ù. ¿øÇüÁú¸·ÀÇ ºÐÀÚ±¸Á¶´Â ·¹½ÃƾÀ̳ª ÄÝ·¹½ºÅ×·Ñ µîÀÇ Ç¥¸é Ȱ¼º¹°Áú ºÐÀÚ°¡ 2ºÐÀÚÃþÀ¸·Î ±× Ç¥¸é¿¡ ¹è¿µÇ¸ç, À̰ÍÀ» °¢ 1ºÐÀÚÃþÀÇ ´Ü¹éÁú ºÐÀÚ°¡ ¾çÂÊ¿¡¼ »÷µåÀ§Ä¡ÇÑ ´ÜÀ§¸· ±¸Á¶ÀÌ´Ù. ÀüÀÚÇö¹Ì°æÀûÀ¸·Î ÀÌ ´ÜÀ§´Â ¾Ï-¸í-¾ÏÀÇ 3Ãþ(°¢ ¾à 20nm)À¸·Î ±¸º°µÈ´Ù. ¿øÇüÁúÀÇ Åõ°ú¼º¿¡ Áß¿äÇÑ ±¸½ÇÀ» Çϸç, »ý¸®»óŰ¡ º¯ÇÏ¸é ±× Åõ°ú¼ºµµ ½Å¼ÓÈ÷ º¯ÇÑ´Ù. ¶Ç, ¼Õ»óÀÌ µÇ¸é ½±°Ô »õ·Î Çü¼ºµÈ´Ù. |
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| PM | after death (Lat. post mortem); after noon [Lat. post meridiem]; mean pressure; pacemaker; pantomogr... |
|---|---|
| PA | panic attack; pantothenic acid; paralysis agitans; paranoia; passive aggressive; pathology; patient'... |
| SCM | Schwann cell membrane; sensation, circulation, and motion; Society of Computer Medicine; soluble cyt... |
| PAF | paroxysmal atrial fibrillation; peroxisomal assembly factor; phosphodiesterase-activating factor; pl... |
| PC | avoirdupois weight [Lat. pondus civile]; packed cells; paper chromatography; paracortex; parent cell... |
| AFGP | Antifreeze glycoproteins |
|---|---|
| DAG | Dystrophin Associated Glycoproteins |
| GPIIIa | Glycoproteins IIb and IIIa |
| mucins | mucous glycoproteins |
| PSG | Pregnancy specific glycoproteins |
| platelet membrane glycoproteins | Surface glycoproteins on platelets which have a key role in haemostasis and thrombosis such as platelet adhesion and aggregation. Many of these are receptors. (12 Dec 1998) |
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| membrane glycoproteins | Glycoproteins found on the membrane or surface of cells. (12 Dec 1998) |
|---|---|
| variant surface glycoproteins, trypanosoma | Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection. (12 Dec 1998) |
| glycoproteins | Conjugated proteins containing one or more covalently linked carbohydrate residues. While technically describing conjugates in which the carbohydrate is less than 4 per cent by weight, the term is often used generically to include the mucoproteins and proteoglycans. (12 Dec 1998) |
| haemagglutinin glycoproteins, influenza virus | Membrane glycoproteins from influenza viruses which are involved in haemagglutination, virus attachment, and envelope fusion. Fourteen distinct subtypes of ha glycoproteins and nine of na glycoproteins have been identified from influenza a virus; no subtypes have been identified for influenza b or influenza c viruses. (12 Dec 1998) |
| acquired platelet function defect | <haematology> Platelet function can be affected by a number of different disease processes including polycythaemia vera, leukaemia, myelofibrosis, renal failure, multiple myeloma and some medications (for example penicillins, salicylates, phenothiazines). Disturbed blood clotting can be manifested by: easy bruising, bleeding gums, nosebleeds, abnormal vaginal bleeding, rectal bleeding, skin rash, vomiting blood, coughing up blood or blood in the urine. A measure of bleeding time and coagulation profile will be part of the evaluation. (29 Dec 1997) |
| antigens, human platelet | Human alloantigens expressed only on platelets, specifically on platelet membrane glycoproteins. These platelet-specific antigens are immunogenic and can result in pathological reactions to transfusion therapy. (12 Dec 1998) |
| anti-platelet agents | Medications that, like aspirin, reduce the tendency of platelets in the blood to clump and clot. (12 Dec 1998) |
| receptors, platelet-derived growth factor | Specific molecular sites or structures on cell membranes that react with platelet-derived growth factor, its analogs, or antagonists, to elicit or to inhibit the specific response of the cell to this factor. Pdgf binds with different affinities and specificities to two structurally related receptors, the alpha-receptor and the beta-receptor. Both of these receptors are transmembrane proteins with an intracellular, ligand-stimulatable protein kinase domain. (12 Dec 1998) |
| medication, anti-platelet | Platelet-blocking drugs. Drugs that, like aspirin, reduce the tendency of platelets in the blood to clump and clot. (12 Dec 1998) |
| platelet | <haematology> A discoid cell (3m diameter) found in large numbers in blood, important for blood coagulation and for haemostasis by repairing breaches (small breaks) in the walls of blood vessels. Platelet _ granules contain lysosomal enzymes, dense granules contain ADP (a potent platelet aggregating factor) and serotonin (a vasoactive amine). They also release platelet-derived growth factor which presumably contributes to later repair processes by stimulating fibroblast proliferation. Synonym: thrombocytes. (09 Oct 1997) |
| platelet-activating factor | <cytokine> Potent phospholipid activator and mediator of many leucocyte functions, including platelet aggregation, inflammation, and anaphylaxis. It is produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells. Several molecular species of platelet-activating factor have been identified which vary in the length of the O-alkyl side chain. It is an important mediator of bronchoconstriction. Synonym: platelet-aggregating factor. Acronym: PAF (20 Sep 2002) |
| platelet activation | A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable haemostatic plug. (12 Dec 1998) |
| platelet actomyosin | The contractile protein of platelets, responsible for clot retraction, platelet aggregation, and release of ADP and other biologic amines essential to platelet function. Synonym: thrombosthenin. (05 Mar 2000) |
| platelet adhesiveness | The process whereby platelets adhere to something other than platelets, e.g., collagen, basement membranes, microfibrils, or other "foreign" surfaces. (12 Dec 1998) |
| platelet-aggregating factor | <cytokine> Potent phospholipid activator and mediator of many leucocyte functions, including platelet aggregation, inflammation, and anaphylaxis. It is produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells. Several molecular species of platelet-activating factor have been identified which vary in the length of the O-alkyl side chain. It is an important mediator of bronchoconstriction. Synonym: platelet-aggregating factor. Acronym: PAF (20 Sep 2002) |
Synonyms : PM-GPs, Platelet Glycoproteins, Glycoproteins, Platelet, Glycoproteins, Platelet Membrane, Membrane Glycoproteins, Platelet
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