| 영문 | gigantism | 한글 | 거인증 |
|---|---|---|---|
| 설명 | 뇌하수체의 성장호르몬을 분비하는 세포에서 종양이 생겼을 경우에 과도한 성장 호르몬의 생성으로 발생되는 병이다. 뼈에서 길이의 성장을 담당하는, 연골로 구성되어 있는 부위인 뼈끝이 연골에서 뼈가 생성 되어서 뼈의 길이의 성장이 일어난다. 성장이 다 된 뼈에서는 이 연골판이 없어지게 되어 양쪽의 뼈가 융합이 되고 이것이 있던 부위에 하나의 선만이 남게 된다. 뼈끝 융합이 일어나기 전에 종양이 생겼을 때는 거인증(giantism)이 일어나지만 뼈끝융합이 일어난 후에 생겼을 때는 말단비대증(acromegaly)이라는 병이 일어난다. 거인증은 소아기에는 매우 드물며, 대부분이 과도한 성장이 있는 사춘기에 일어난다. 과도한 성장호르몬의 분비에 의해서 뼈, 연골, 섬유조직 등의 과도한 성장이 있게 된다. 일반적으로 자각 증상은 없는 경우가 보통이며 있는 경우도 있지만 아주 경미하다. 머리뼈나 아래턱뼈가 아주 두터워지고 모든 뼈의 굵기나 크기가 증가된다. 뼈의 기능은 모두 정상이나 근육의 힘이 약해 있는 것이 대부분이다. 검사상으로 혈액중에 성장 호르몬치가 높으며, 치료는 외과적으로 뇌하수체에 생긴 종양을 절제하는 방법과 방사선을 쬐어서 그 종양을 없애는 방법이 있다. |
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| 영문 | hypophysis, pituitary | 한글 | 뇌하수체 |
|---|---|---|---|
| 설명 | 뇌바닥부에 있으며 터어키안장에 위치하는 이중기원의 상피성 소체. 중요한 내분비 장기 중 하나이다. 전엽, 중엽, 후엽의 세 부분으로 이루어져 있고, 다른 내분비선의 활동을 지배하는 호르몬을 분비하며, 생식과 발육에 밀접한 관계가 있다. |
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| DGS | decompression sickness; developmental Gerstmann syndrome; diabetic glomerulosclerosis; Di George seq... |
|---|---|
| DGSX | X-linked dysplasia gigantism syndrome |
| EMG | electromyogram, electromyography; eye movement gauge; exomphalosmacroglossia-gigantism [syndrome] |
| HCG, hCG | Human Chorionic Gonadotropin; 사람융모성성선자극호르몬 1. Placental Glycoprotein Hormone &nbs... |
| HPA axis | Hypothalamic-Pituitary-Adrenal axis |
| AP | Anterior pituitary |
|---|---|
| APs | Anterior pituitary glands |
| BPE | Bovine pituitary extract |
| CPHD | Combined pituitary hormone deficiency |
| HPA | Hypothalamic-Pituitary-Adrenal |
| pituitary gigantism | Excessive growth due to overactivity of the pituitary gland (specifically of the anterior pituitary). (12 Dec 1998) |
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| acromegalic gigantism | A form of pituitary gigantism in which the signs of acromegaly accompany abnormal height. (05 Mar 2000) |
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| gigantism | A condition where there is over-production of growth hormone by the pituitary gland in a child before the bone growth plates close, resulting in excessive long bone growth. (27 Sep 1997) |
| cerebral gigantism | A syndrome characterised by increased birth weight and length (above 90th percentile), accelerated growth rate for the first 4 or 5 years without elevation of serum growth hormone levels, and then reversion to normal growth rate; characteristic facies include prognathism, hypertelorism, antimongoloid slant, and dolichocephalic skull; moderate mental retardation and impaired coordination are also associated. See: Sotos' syndrome. (05 Mar 2000) |
| primordial gigantism | Unusually large size from birth due to familial or genetic factors or intrauterine environment (e.g., maternal prediabetic state) and not to hyperpituitarism. (05 Mar 2000) |
| eunuchoid gigantism | Gigantism with deficient development of sexual organs; may be of pituitary or gonadal origin; gigantism accompanied by body proportions typical of hypogonadism during adolescence. (05 Mar 2000) |
| focal gigantism | <radiology> Neurofibromatosis, AVM, Klippel-Trenaunay-Weber syndrome, Beckwith-Wiedemann syndrome, Parks-Davis syndrome, haemangioma, JRA (12 Dec 1998) |
| foetal gigantism | Excessive foetal or newborn size, e.g., cerebral gigantism and infants of diabetic mothers. (05 Mar 2000) |
| anterior pituitary gonadotropin | Any gonadotropin of hypophysial origin; formerly used to designate a single hormone, because it was thought that the anterior hypophysis secreted only one gonadotropin. Synonym: pituitary gonadotropic hormone. (05 Mar 2000) |
| anterior pituitary-like hormone | A glycoprotein with a carbohydrate fraction composed of d-galactose and hexosamine, extracted from the urine of pregnant women and produced by the placental trophoblastic cells; its most important role appears to be stimulation, during the first trimester, of ovarian secretion of the oestrogen and progesterone required for the integrity of conceptus; it appears to play no significant role in the last two trimesters of pregnancy, as the oestrogen and progesterone are then formed by the placenta. Synonym: anterior pituitary-like hormone, choriogonadotropin, chorionic gonadotropic hormone, chorionic gonadotrophic hormone, placenta gonadotropin, placentagonadotropin. (05 Mar 2000) |
| receptors, pituitary hormone | Cell surface proteins that bind pituitary hormones with high affinity and trigger intracellular changes influencing the behaviour of cells. Since many pituitary hormones are also released by neurons as neurotransmitters, these receptors are also found in the nervous system. (12 Dec 1998) |
| receptors, pituitary hormone-regulating hormone | Cell surface receptors that bind the hypothalamic hormones regulating pituitary cell differentiation, proliferation, and hormone synthesis and release, including the pituitary-releasing and release-inhibiting hormones. The pituitary hormone-regulating hormones are also released by cells other than hypothalamic neurons, and their receptors also occur on non-pituitary cells, especially brain neurons, where their role is less well understood. Receptors for dopamine, which is a prolactin release-inhibiting hormone as well as a common neurotransmitter, are not included here. (12 Dec 1998) |
| pharyngeal pituitary | The embryonic remnant of the oral end of Rathke's pouch that is cut off from the adenohypophysis by the developing sphenoid bone; composed chiefly of chromophobes and, under normal conditions, considered physiologically inactive. See: hypophysis. (05 Mar 2000) |
| pituitary | <anatomy, endocrinology> An endocrine gland located at the base of the brain, in the small recess of a bone - certain sections of the pituitary each secretes important hormones including growth hormone (GH) and antidiuretic hormone (ADH). (16 Dec 1997) |
| pituitary adamantinoma | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| pituitary adenoma | <radiology> Benign, slow-growing, arises from adenohypophysis (anterior lobe), 5-18% of all intracranial neoplasms plain film (unreliable): enlargement of sella and sloping of the sella floor, erosion of the anterior and posterior clinoid, erosion of the dorsum sellae, calcified in less than10%, may present as a mass in the nasopharynx functioning microadenoma, less than10 mm, 20-30% of pituitary adenomas, types: prolactinoma, corticotrophic adenoma, somatotrophic adenoma, nonfunctioning macroadenoma, more than 10 mm, 70-80% of pituitary adenomas (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|