| DLI | distolinguoincisal; double label index |
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| 32P | 2) photoaffinity labeling with |
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| photoaffinity labelling | <technique> A technique for covalently attaching a label or marker molecule onto another molecule such as a protein. The label, which is often fluorescent or radioactive, contains a group that becomes chemically reactive when illuminated usually with ultraviolet light) and will form a covalent linkage with an appropriate group on the molecule to be labelled: proximity is essential. The most important class of photoreactive groups used are the aryl azides, which form short lived but highly reactive nitrenes when illuminated. (31 Dec 1997) |
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| photoaffinity labels | Biologically active molecules which are covalently bound to the enzymes or binding proteins normally acting on them. Binding occurs due to activation of the label by ultraviolet light. These labels are used primarily to identify binding sites on proteins. (12 Dec 1998) |
| radio label | A mildly radioactive molecule that is used to tag another molecule (such as a protein) so that it can be identified as it goes through some kind of biochemical process. (09 Oct 1997) |
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| chromogenic label | A molecule which can be used as a label to a biological probe molecule because it forms a coloured compound when the probe molecule is attached to its target. (09 Oct 1997) |
| off-label | Use of a drug for a disease or condition other than the indication for which it was approved by the FDA. For example: many doctors prescribe paromomycin (humatin) for cryptosporidiosis, although it is not approved for treating this disease. (09 Oct 1997) |
| off-label use | In the United States, the regulations of the Food and drug administration (FDA) permit physicians to prescribe approved medications for other than their intended indications. This practice is known as off-label use. (12 Dec 1998) |
| open-label trial | A study in which both researchers and participants know what drug a person is taking and at what dose. (09 Oct 1997) |
| label | 1. To incorporate into a compound a substance that is readily detected, such as a radionuclide, whereby its metabolism can be followed or its physical distribution detected. 2. The substance so incorporated. (05 Mar 2000) |
| fluorescent label | A molecule which fluoresces and can be attached to a probe molecule that does not fluoresce. (09 Oct 1997) |
Synonyms : Labels, Photoaffinity
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