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"phosphatidylinositol 4,5-diphosphate"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
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  • phosphatidylinositol-4,5- biphosphate(pip2)
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  • phosphatidylinositol-4,5- biphosphate(pip2)
    Æ÷½ºÆÄƼµô¸®³ë½ÃÅç-4,5-ºñÆ÷½ºÆäÀÌÆ®
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  • phosphatidylinositol
    Æ÷½ºÆÄƼµôÀ̳ë½ÃÅç
  • phosphatidylinositol cycle
    Æ÷½ºÆÄƼµôÀ̳ë½ÃÅç ȸ·Î(üÞÖØ)
  • phosphatidylinositol response
    Æ÷½ºÆÄƼµô ´ëÀÀ(Óßëë)
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PI first meiotic prophase; isoelectric point; pacing impulse; package insert; pancreatic insufficiency;...
PIGA phosphatidylinositol glycan A
PIP2 phosphatidylinositol 4,5-biphosphate or diphosphate
PI-P phosphatidylinositol-4-phosphate
PI-PP phosphatidylinositol-4,5-biphosphate
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PI 1-phosphatidylinositol
Pl 1-phosphatidylinositol
PtdIns 1-phosphatidylinositol
PI 3-kinase 1-phosphatidylinositol 3-kinase
PtdIns 3-kinase 1-phosphatidylinositol 3-kinase
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
phosphatidylinositol 4,5-diphosphate <biochemistry> A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase c, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase.
(12 Dec 1998)
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phosphatidylinositol <biochemistry> A phosphatidic acid combined with inositol found in biomembranes and a precursor to certain cellular signals. Sometimes referred to as inositide.
It is a very important minor phospholipid in eukaryotes, involved in signal transduction processes. Contains myo inositol linked through the 1 hydroxyl group to phosphatidic acid.
The 4 phosphate (PIP) and 4, 5 bisphosphate derivatives PIP2) are formed and broken down in membranes by the action of specific kinases and phosphatases (futile cycles).
Signal sensitive phospholipase C enzymes remove the inositol moiety, in particular from 1,4,5 trisphosphate (PIP2) as inositol 1,4,5 triphosphate (Ins P3: IP3). Both the diacyl glycerol and products act as second messengers.
Synonym: phosphoinositide.
(20 Sep 2002)
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase <enzyme> Hydrolyzes the 5-position phosphate of ptdins(3,4,5)p3 forming phosphatidylinositol-3,4-bisphosphate; an isoenzyme forms a complex with the p85/p110 form of pi 3-kinase
Registry number: EC 3.1.3.-
Synonym: ptdins(3,4,5)p3 5-phosphatase, pi(3,4,5)p3 5-pase
(26 Jun 1999)
phosphatidylinositol-3-phosphatase <enzyme> Hydrolyzes phosphatidylinositol 3-phosphate in nih 3t3 cells; specific as it has little or no activity on the monoester phosphates of ptdins(4)p, ptdins(4,5)p2, or inositol 1,3-bisphosphate; does not require added metal ions for activity and is maximally active in the presence of edta; inhibited by ca(2+), mg(2+),zn(2+), and the phosphatase inhibitor vo(3-)4
Registry number: EC 3.1.3.64
Synonym: phosphatidylinositol 3-phosphatase
(26 Jun 1999)
phosphatidylinositol 4,5-bisphosphate <biochemistry> This is a molecule of phosphatidylinositol with two additional sites of phosphorylation.
It is an important constituent of cell membrane phospholipids as well as a precursor of the second messengers, diacylglycerol and inositol 1,4,5-trisphosphate.
Acronym: PIP2
(20 Sep 2002)
phosphatidylinositol 4,5-bisphosphate kinase <enzyme> Membrane-associated enzyme
Registry number: EC 2.7.1.-
Synonym: ptdins 4,5-p2 kinase, phosphatidylinositol 4,5-bisphosphate kinase, ptdins(4,5)p2 3oh-kinase
(26 Jun 1999)
phosphatidylinositol 4-phosphate <biochemistry> The intermediate in the biosynthesis of phosphatidylinositol 4,5-bisphosphate from phosphatidylinositol.
(20 Sep 2002)
phosphatidylinositol 4-phosphate phosphatase <enzyme> From human erythrocyte membranes
Registry number: EC 3.1.3.-
Synonym: ptdins-4p-phosphatase, phosphatidylinositol-4-phosphate monoesterase, ptdins4p monoesterase
(26 Jun 1999)
phosphatidylinositol-ceramide phosphoinositol transferase <enzyme> Involved in biosynthesis of inositol-containing sphingolipids; isolated from saccharomyces cerevisiae
Registry number: EC 2.4.1.-
Synonym: ipc synthase
(26 Jun 1999)
phosphatidylinositol phosphates <biochemistry> Phosphatidylinositols in which one or more alcohol group of the inositol has been substituted with a phosphate group.
(12 Dec 1998)
phosphatidylinositol synthase <enzyme> An enzyme that catalyses the reaction of CDP-diacylglycerol with inositol to form CMP and phosphatidylinositol; found in the endoplasmic reticulum.
(20 Sep 2002)
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase <enzyme> Involved in formation of glycosylphosphatidyl inositol membrane anchors in trypanosoma brucei; forms glucosaminyl-phosphatidylinositol
Registry number: EC 3.5.1.-
Synonym: glcnac-pi de-n-acetylase, pig-l protein, phosphatidylinositol glycan class l protein, n-acetylglucosaminyl-phosphatidylinositol deacetylase
(26 Jun 1999)
1-phosphatidylinositol 3-kinase <enzyme> An enzyme that catalyses the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, v(d)j recombination and cell cyle checkpoints.37.
Chemical name: ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
Registry number: EC 2.7.1.137
(12 Dec 1998)
1-phosphatidylinositol 4-kinase <enzyme> An enzyme that catalyses the conversion of phosphatidylinositol to phosphatidylinositol 4-phosphate, the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.
Chemical name: ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate
Registry number: EC 2.7.1.67
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 1 ÆäÀÌÁö: 1
  • Phosphatidylinositol 4,5-Diphosphate - »õâ A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
    Synonyms : Phosphatidylinositol 4, 5-Biphosphate, PtIns 4, 5-P2, 4, 5-Biphosphate, Phosphatidylinositol, 4, 5-Diphosphate, Phosphatidylinositol, Phosphatidylinositol 4, 5 Biphosphate, Phosphatidylinositol 4, 5 Bisphosphate, Phosphatidylinositol 4, 5 Diphosphate
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