| 영문 | phenylketonuria(=PKU) | 한글 | 페닐케톤뇨증 |
|---|---|---|---|
| 설명 | 선천병으로 체내에 페닐케톤이 축적되어 오줌으로 나오는 병이다. 폐닐케톤이 축적되는 이유는 인체내에 페닐알라닌(phenylalanine)이라는 아미노산을 다른 아미노산인 티로신으로 바꾸어 주는 한 효소(phenylalanine hydroxylase)가 선천적으로 결핍되어 태어나기 때문이다. 이 효소의 결핍이 있으면, 계속적인 페닐알라닌의 축적이 일어나고, 결국은 페닐케톤의 축적으로 발전한다. 신체내의 높은 페닐케톤농도는 태아의 뇌발달을 억제하여 결국은 정신지체를 유발한다. 따라서 이 질병은 빠른 진단으로, 페닐알라닌이 적은 식사(저단백질 식사)를 뇌의 발달이 완전히 멈추는 성인까지 시행하면, 자연히 치료된다. 신생아에서 이 질병의 존재를 알기 위해 오줌이나 혈액내에서, 페닐케톤의 유무를 알아보기도 하며, 구뜨리 진단법(Guthrie's test)을 시행한다. |
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| PKU | phenylketonuria |
|---|---|
| HCG, hCG | Human Chorionic Gonadotropin; 사람융모성성선자극호르몬 1. Placental Glycoprotein Hormone &nbs... |
| MHP | hemiplegic migraine; maternal health program; maternal health program; medical center health plan; 1... |
| MSAFP | Maternal Serum Alpha(α)-Feto-Protein |
| AAMIH | American Association for Maternal and Infant Health |
| PKU | Phenylketonuria |
|---|---|
| AMA | Advanced maternal age |
| MCH | Maternal Child Health |
| MSAFP | Maternal Serum Alpha Feto Protein |
| MSS | Maternal Serum Screening |
| phenylketonuria, maternal | Phenylketonuria in a pregnant woman. The maternal disease puts the foetus at great risk of mental retardation and other congenital diseases. (12 Dec 1998) |
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| phenylketonuria | <disease> Congenital absence of phenylalanine hydroxylase (an enzyme that converts phenylalanine into tyrosine). Phenylalanine accumulates in blood and seriously impairs early neuronal development. The defect can be controlled by diet and is not serious if treated in this way. Incidence: highest in Caucasians. Acronym: PKU Origin: Gr. Ouron = urine (15 Oct 1997) |
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| nonclassical phenylketonuria | DHPR-deficient form; an inherited disorder in which there is an absence or deficiency of dihydropteridine reductase (DHPR); this results in impaired regeneration of tetrahydrobiopterin, causing an elevation in phenylalanine levels, GTP-CH form; an inherited disorder in which there is a deficiency of guanosine triphosphate cyclohydrolase, an enzyme used in the biosynthesis of tetrahydrobiopterin, 6-PTS form; an inherited disorder in which there is a deficiency of 6-pyruvoyl tetrahydropterin synthase, an enzyme that participates in the biosynthesis of tetrahydrobiopterin. Synonym: nonclassical phenylketonuria. (05 Mar 2000) |
| rate, maternal mortality | The number of maternal deaths related to childbearing divided by the number of live births (or by the number of live births + foetal deaths) in that year. The maternal mortality rate in the united states in 1993 (and 1994) was 0.1 per 1,000 live births, or 1 mother dying per 10,000 live births. (12 Dec 1998) |
| maternal | Relating to or derived from the mother. Origin: L. Maternus, fr. Mater, mother (05 Mar 2000) |
| maternal age 35 and over | Pregnancy in women 35 or more years of age. It is used for normal pregnancies and for problems of pregnancy occurring in a woman's late reproductive years. These include effects on the mother's physical and mental health as well as risks of perinatal mortality and foetal abnormality. (12 Dec 1998) |
| maternal antibody | Any antibody transferred from a mammalian mother transplacentally into the foetus. See under immunoglobulin for details of the classes of Ig that are transferred to the foetus. (18 Nov 1997) |
| maternal behaviour | The behaviour patterns associated with or characteristic of a mother. (12 Dec 1998) |
| maternal-child health centres | Facilities which administer the delivery of health care services to mothers and children. (12 Dec 1998) |
| maternal-child nursing | The nursing specialty that deals with the care of women throughout their pregnancy and childbirth and the care of their newborn children. (12 Dec 1998) |
| maternal cotyledon | A unit of the placenta made up of trophoblastic cells, fibrous tissue, and abundant blood vessels, which is visible grossly on the maternal surface as an irregularly shaped lobe circumscribed by a deep cleft and made up of a stem villus with numerous branching free villi and anchoring villi; placental vessels in the chorionic plate supply the stem villus and its branches, allowing gas and metabolite exchange across the trophoblastic layer with maternal blood in the intervillous space; traditionally called clinicians' cotyledon. (05 Mar 2000) |
| maternal death | Death of a woman while pregnant or within 42 days after the termination of gestation, irrespective of the duration and site of pregnancy and the cause of death; two periods are recognised in the 42-day interval: period 1 includes day 1 to day 7; period 2 includes day 8 to day 42. Maternal death's are further classified as: (05 Mar 2000) |
| maternal death rate | The number of maternal deaths that occur as the direct result of the reproductive process per 100,000 live births. See: rate. See: maternal death. (05 Mar 2000) |
| maternal deprivation | Prolonged separation of the offspring from the mother. (12 Dec 1998) |
| maternal deprivation syndrome | <syndrome> A failure to thrive seen in infants and young children and exhibited as a constellation of physical signs, symptoms, and behaviours, usually associated with maternal loss, absence or neglect, and characterised by lack of responsiveness to the environment and often depression. (05 Mar 2000) |
| maternal dystocia | Dystocia caused by an abnormality or physical problem in the mother. (05 Mar 2000) |
Synonyms : Maternal Phenylketonuria, PKU, Maternal, Phenylalanine-Hydroxylase Deficiency Disease, Maternal, Phenylketonuria, Pregnancy in, Phenylketonurias, Pregnancy in, Pregnancy in Phenylketonurias, in Phenylketonuria, Pregnancy, in Phenylketonurias, Pregnancy
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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