| DBH | Dopamine-Beta(¥â)-Hydroxylase |
|---|---|
| AHH | alpha-hydrazine analog of histidine; anosmia and hypogonadotropic hypogonadism [syndrome]; arylhydro... |
| DBH | dopamine beta-hydroxylase |
| PPH | past pertinent history; persistent pulmonary hypertension; phosphopyruvate hydratase; postpartum hem... |
| TH | tension headache; tetrahydrocortisol; T helper [cell]; theophylline; thorax; thrill; thyrohyoid; thy... |
| PAH | Phenylalanine hydroxylase |
|---|---|
| PH | Phenylalanine hydroxylase |
| D-Phe | D-Phenylalanine |
| Phe | D-phenylalanine |
| FMLP | Formyl methionyl leucyl phenylalanine |
| phenylalanine hydroxylase | <enzyme> An enzyme of the oxidoreductase class that catalyses the reaction l-phenylalanine, tetrahydrobiopterin, and oxygen to yield l-tyrosine, dihydrobiopterin, and water, the reaction synthesizing tyrosine from phenylalanine. Chemical name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) Registry number: EC 1.14.16.1 (12 Dec 1998) |
|---|---|
| phenylalanine hydroxylase phosphatase | <enzyme> Catalyses dephosphorylation of phosphorylated phenylalanine hydroxylase Registry number: EC 3.1.3.- Synonym: phe hydroxylase phosphatase (26 Jun 1999) |
| phenylalanine 4-hydroxylase | <enzyme> An enzyme that catalyses the oxidation of l-phenylalanine to l-tyrosine with O2 and tetrahydrobiopterin (the latter forming the dihydro derivative) which is reduced by NADPH and a reductase to the active form; a deficiency of either of these enzymes will result in phenylketonuria. Synonym: phenylalanine 4-hydroxylase. (05 Mar 2000) |
|---|---|
| phenylalanine | <amino acid> One of the amino acids which the body cannot manufacture itself, but must acquire from food. It is abundant in meats and cheese. Phenylalanine is a precursor of tyrosine and together they lead to the formation of thyroxine or thyroid hormone and of adrenaline and noradrenaline which is converted into a neurotransmitter, a brain chemical which transmits nerve impulses. This neurotransmitter is used by the brain to manufacture noradrenaline which promotes mental alertness, memory, elevates mood and suppresses the appetite very effectively. Along with another amino acid, tryptophan, phenylalanine governs the release of an intestinal hormone called cholecystokinin. Overuse of phenylalanine supplements can cause anxiety, headaches and hypertension and are contraindicated for pregnant woman, those who suffer from anxiety attacks, high blood pressure, PKU, pigmented melanoma or anyone taking an anti-depressant containing monoamine oxidase inhibitors. (15 Oct 1997) |
| phenylalanine 4-monooxygenase | <enzyme> An enzyme that catalyses the oxidation of l-phenylalanine to l-tyrosine with O2 and tetrahydrobiopterin (the latter forming the dihydro derivative) which is reduced by NADPH and a reductase to the active form; a deficiency of either of these enzymes will result in phenylketonuria. Synonym: phenylalanine 4-hydroxylase. (05 Mar 2000) |
| phenylalanine aminopeptidase | <enzyme> Metalloenzyme from legionella pneumophila; mw: 35,000; pH optimum 8-9.5 Registry number: EC 3.4.11.- (26 Jun 1999) |
| phenylalanine ammonia lyase | <enzyme> An enzyme that catalyses the deamination of l-phenylalanine to form trans-cinnamate and ammonia. It may also act on l-tyrosine. Since the enzyme deprives neoplastic tissue of phenylalanine, it has been used experimentally in the treatment of acute lymphoblastic leukaemia. The enzyme is obtained from many plants and is used as an enzymic marker for lignification and other developmental processes in plant cells. Pharmacological action: antineoplastic agent. Chemical name: L-Phenylalanine ammonia-lyase Registry number: EC 4.3.1.5 (12 Dec 1998) |
| phenylalanine oxidase | <enzyme> Forms phenylpyruvate in the presence of air; consider also phenylalanine dehydrogenase (nad) which requires nad Registry number: EC 1.4.3.- Synonym: phenylalanine desaminase, l-phenylalanine oxidase, phenylalanine dehydrogenase (26 Jun 1999) |
| phenylalanine-trna ligase | <enzyme> An enzyme that activates phenylalanine with its specific transfer RNA. Chemical name: Phenylalanine:tRNA(Phe) ligase (AMP-forming) Registry number: EC 6.1.1.20 (12 Dec 1998) |
| n-formylmethionine leucyl-phenylalanine | <chemical> N-formylmethionyl-leucyl-phenylalanine. A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated. Chemical name: L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- (12 Dec 1998) |
| N-formylmethionyl-leucyl-phenylalanine carboxypeptidase | <enzyme> Human salivary enzyme liberates phenylalanine from the chemotactic peptide n-formylmethionine leucyl-phenylalanine Registry number: EC 3.4.- Synonym: n-formyl-methionine leucyl-phenylalanyl carboxypeptidase, formylmet-leu-phe carboxypeptidase (26 Jun 1999) |
| abscisic acid 8'-hydroxylase | <enzyme> Catalyses conversion of abscisic acid to 8'-hydroxyabscisic acid, which rearranges to phaseic acid Registry number: EC 1.14.99.- Synonym: aba 8'-hydroxylase (26 Jun 1999) |
| aflatoxin B1 hydroxylase | <enzyme> Hydroxylases may be replaced by mixed function oxidases as appropriate Registry number: EC 1.14.- Synonym: aflatoxin b1 4-hydroxylase (26 Jun 1999) |
| aklavinone 11-hydroxylase | <enzyme> A flavin-type bacterial hydroxylase from streptomyces peucetius; 489 amino acid residues, mw 52.3 kD; genbank u09844 Registry number: EC 1.14.14.- Synonym: dnrf protein, dnrf gene product (26 Jun 1999) |
| aniline hydroxylase | <enzyme> A drug-metabolizing, cytochrome p-450 enzyme which catalyses the hydroxylation of aniline to hydroxyaniline in the presence of reduced flavoprotein and molecular oxygen. Registry number: EC 1.14.14.- (12 Dec 1998) |
| arachidonic acid 18-hydroxylase | <enzyme> Converts arachidonic acid to 18-hydroxy-5,8,11,14-eicosatetraenoic acid in the presence of NADPH; cytochrome p450 enzyme Registry number: EC 1.14.13.- Synonym: arachidonic acid 18(r)-hydroxylase, arachidonic acid omega 3-hydroxylase (26 Jun 1999) |
| arylamine N-hydroxylase | <enzyme> Cytochrome p-448 dependent Registry number: EC 1.14.13.- Synonym: 2-aminofluorene n-hydroxylase (26 Jun 1999) |
Synonyms : Phenylalanine 4-Hydroxylase, Phenylalanine 4-Monooxygenase, 4-Hydroxylase, Phenylalanine, 4-Monooxygenase, Phenylalanine, Hydroxylase, Phenylalanine, Phenylalanine 4 Hydroxylase, Phenylalanine 4 Monooxygenase
| phenylalanine hydroxylase |
Phenylalanine hydroxylase (eg. EC 1.14.16.1) is an enzyme which catalyses the reaction causing the addition of an hydroxyl group to the end of the 6-carbon aromatic ring of phenylalanine, such that it becomes tyrosine. Phenylalanine hydroxylase is the rate-limiting enzyme of the metabolic pathway which degrades excess phenylalanine. Mutations in phenylalanine hydroxylase which result in lower activity are the cause of the disease phenylketonuria, or PKU. ...
Ãâó: en.wikipedia.org/wiki/Phenylalanine_hydroxylase
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| phenylalanine hydroxylase deficiency |
phenylketonuria.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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