| 영문 | phenylketonuria(=PKU) | 한글 | 페닐케톤뇨증 |
|---|---|---|---|
| 설명 | 선천병으로 체내에 페닐케톤이 축적되어 오줌으로 나오는 병이다. 폐닐케톤이 축적되는 이유는 인체내에 페닐알라닌(phenylalanine)이라는 아미노산을 다른 아미노산인 티로신으로 바꾸어 주는 한 효소(phenylalanine hydroxylase)가 선천적으로 결핍되어 태어나기 때문이다. 이 효소의 결핍이 있으면, 계속적인 페닐알라닌의 축적이 일어나고, 결국은 페닐케톤의 축적으로 발전한다. 신체내의 높은 페닐케톤농도는 태아의 뇌발달을 억제하여 결국은 정신지체를 유발한다. 따라서 이 질병은 빠른 진단으로, 페닐알라닌이 적은 식사(저단백질 식사)를 뇌의 발달이 완전히 멈추는 성인까지 시행하면, 자연히 치료된다. 신생아에서 이 질병의 존재를 알기 위해 오줌이나 혈액내에서, 페닐케톤의 유무를 알아보기도 하며, 구뜨리 진단법(Guthrie's test)을 시행한다. |
||
| DMPEA | 3,4-Di-Methoxy-Phenyl-Ethyl-Amine |
|---|---|
| DOPA | 3,4-Dihydr-Oxy-Phenyl-Alanine |
| L-PAM | L-Phenyl-Alanine Mustard = Melphalan |
| MHPG | 3-Methoxy-4-Hydroxy-Phenyl Glycol |
| PEMA | Phenyl-Ethyl-Malonanide |
| MPP+ | methyl phenyl pyridinium |
|---|---|
| NPN | 1-N-phenyl-naphthylamine |
| PDMP | 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol |
| PMP | 1-Phenyl-3-methyl-5-pyrazolone |
| PBN | 1-alpha-phenyl-tert-butyl nitrone |
| phenyl | <chemistry> A hydrocarbon radical (C6H5) regarded as the essential residue of benzene, and the basis of an immense number of aromatic derivatives. <chemistry> Phenyl hydrate, a nitrogenous base (C6H5.N2H3) produced artificially as a colourless oil which unites with acids, ketones, etc, to form well-crystallized compounds. Origin: Gr. To bring to light + -yl: cf. F. Phenyle. So called because it is a by-product of illuminating gas. Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| phenyl alcohol | <chemistry> 1. A white or pinkish crystalline substance, C6H5OH, produced by the destructive distillation of many organic bodies, as wood, coal, etc, and obtained from the heavy oil from coal tar. It has a peculiar odour, somewhat resembling creosote, which is a complex mixture of phenol derivatives. It is of the type of alcohols, and is called also phenyl alcohol, but has acid properties, and hence is popularly called carbolic acid, and was formerly called phenic acid. It is a powerful caustic poison, and in dilute solution has been used as an antiseptic. 2. Any one of the series of hydroxyl derivatives of which phenol proper is the type. <chemistry> Glacial phenol, any one of a series of compounds having both phenol and aldehyde properties. Phenol phthalein. See Phthalein. Origin: Gr. To show + -ol: cf. F. Phenol. Source: Websters Dictionary (01 Mar 1998) |
| phenyl aminosalicylate | P-aminosalicylic acid phenyl ester;an antituberculous drug. Phenyl salicylate, the salicylic ester of phenol; the phenylic ester of salicylic acid; an intestinal analgesic and antipyretic; it has been used in the treatment of rheumatism, diarrhoea, and pharyngitis, as an enteric coating for tablets, and in ointments for sunburn prevention. Synonym: salol. (05 Mar 2000) |
| phenylacetaldehyde dehydrogenase | <enzyme> From E coli; catalyses the oxidation of phenylacetaldehyde to phenylacetic acid in the presence of nad+ Registry number: EC 1.2.1.39 Synonym: phenylacetaldehyde-nad+ oxidoreductase (26 Jun 1999) |
| phenylacetate - CoA ligase | <enzyme> Catalyses the synthesis of phenylacetyl-CoA and phenoxyacetyl-CoA Registry number: EC 6.2.1.30 Synonym: phenylacetyl-CoA ligase, phenylacetic acid activating enzyme, phenoxyacetic acid activating enzyme, phenacyl coenzyme a ligase, phenylacetate-CoA ligase (AMP-forming) (26 Jun 1999) |
| phenylacetic acid | C6H5CH2COOH;an abnormal product of phenylalanine catabolism, appearing in the urine in individuals with phenylketonuria. (05 Mar 2000) |
| phenylaceturic acid | C6H5CH2CO-NH-CH2COOH;an end product of the metabolism of phenylated fatty acids with even numbers of carbon atoms. Synonym: phenylaceturic acid. (05 Mar 2000) |
| phenylacetylurea | An anticonvulsant used in the treatment of epilepsy. Synonym: phenylacetylurea. (05 Mar 2000) |
| phenylacrylic acid | C6H5CH==CHCOOH; 3-phenylpropenoic acid;obtained from cinnamon oil, Peruvian and tolu balsams, or storax. It has been used in lupus as paint and in infectious diseases to promote leukocytosis. Synonym: cinnamylic acid, phenylacrylic acid. (05 Mar 2000) |
| phenylacrylic acid decarboxylase | <enzyme> Confers resistance to phenylacrylic acids in yeasts; enzyme from bacillus pumilus catalyses nonoxidative conversion of ferulic acid and p-coumaric acid to 4-vinylguaiacol and 4-vinylphenol, respectively; amino acid sequence in first source Registry number: EC 4.1.1.- Synonym: cinnamic acid decarboxylase, ferulate decarboxylase, pad1 gene product, ferulic acid decarboxylase, 4-coumarate decarboylase, p-coumarate decarboxylase (26 Jun 1999) |
| phenylalaninase | Phenylalanine 4-monooxygenase. (05 Mar 2000) |
| phenylalanine | <amino acid> One of the amino acids which the body cannot manufacture itself, but must acquire from food. It is abundant in meats and cheese. Phenylalanine is a precursor of tyrosine and together they lead to the formation of thyroxine or thyroid hormone and of adrenaline and noradrenaline which is converted into a neurotransmitter, a brain chemical which transmits nerve impulses. This neurotransmitter is used by the brain to manufacture noradrenaline which promotes mental alertness, memory, elevates mood and suppresses the appetite very effectively. Along with another amino acid, tryptophan, phenylalanine governs the release of an intestinal hormone called cholecystokinin. Overuse of phenylalanine supplements can cause anxiety, headaches and hypertension and are contraindicated for pregnant woman, those who suffer from anxiety attacks, high blood pressure, PKU, pigmented melanoma or anyone taking an anti-depressant containing monoamine oxidase inhibitors. (15 Oct 1997) |
| phenylalanine 4-hydroxylase | <enzyme> An enzyme that catalyses the oxidation of l-phenylalanine to l-tyrosine with O2 and tetrahydrobiopterin (the latter forming the dihydro derivative) which is reduced by NADPH and a reductase to the active form; a deficiency of either of these enzymes will result in phenylketonuria. Synonym: phenylalanine 4-hydroxylase. (05 Mar 2000) |
| phenylalanine 4-monooxygenase | <enzyme> An enzyme that catalyses the oxidation of l-phenylalanine to l-tyrosine with O2 and tetrahydrobiopterin (the latter forming the dihydro derivative) which is reduced by NADPH and a reductase to the active form; a deficiency of either of these enzymes will result in phenylketonuria. Synonym: phenylalanine 4-hydroxylase. (05 Mar 2000) |
| phenylalanine aminopeptidase | <enzyme> Metalloenzyme from legionella pneumophila; mw: 35,000; pH optimum 8-9.5 Registry number: EC 3.4.11.- (26 Jun 1999) |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | <chemical> 1,2,3,6-tetrahydro-1-methyl-4-phenylpyridine. A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in parkinson disease. These toxic effects can be prevented by the administration of selective monoamine oxidase inhibitors. Since the cellular toxicity of the compound is similar to that observed in idiopathic parkinson disease, experimental studies with this compound can suggest new opportunities for effective therapy. The compound also induces duodenal ulcers. Pharmacological action: dopamine agents. Chemical name: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl- (12 Dec 1998) |
|---|
Synonyms : Ethers, Phenyl, Oxides, Diphenyl
Synonyms :
Synonyms : Endorphenyl, L-Phenylalanine, Phenylalanine, L-Isomer, L-Isomer Phenylalanine, Phenylalanine, L Isomer
Synonyms : Ammonia-Lyase, Phenylalanine, Phenylalanine Ammonia Lyase
Synonyms : Phenylalanine 4-Hydroxylase, Phenylalanine 4-Monooxygenase, 4-Hydroxylase, Phenylalanine, 4-Monooxygenase, Phenylalanine, Hydroxylase, Phenylalanine, Phenylalanine 4 Hydroxylase, Phenylalanine 4 Monooxygenase
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|---|---|---|---|
|
미드린피점안제 - 새창
|
Santen |
E00170121 | Phenylephrine HCl, Tropicamide | 전문의약품 | 급여 |
|
게이어염산페닐에프린점안액 - 새창
|
Geyer |
E01510311 | Phenylephrine HCl | 전문의약품 | 급여 |
|
미드후린2.5%점안액 - 새창
|
Alcon |
E07370131 | Phenylephrine HCl | 전문의약품 | 급여 |
|
오큐론점안액 - 새창
|
안국약품 |
A08502261 | Phenylephrine HCl, Prednisolone acetate, Sulfacetamide sodium | 전문의약품 | 삭제 |
|
하나염산페닐에프린주사1% - 새창
|
하나제약 |
A20450301 | Phenylephrine HCl | 전문의약품 | 급여 | 분업예외의약품 |
|
페네피린코약0.5% - 새창
|
동광제약 |
A01301981 | Phenylephrine HCl | 일반의약품 | 급여 |
|
코리자정 - 새창
|
대우약품공업 |
A05400571 | Phenylpropanolamine HCl | 전문의약품 | 삭제 |
|
바쉬앤드롬염산페닐에프린점안액2.5% - 새창
|
Bausch & Lomb |
W01510201 | Phenylephrine HCl | 전문의약품 | 급여 |
|
빌리폰연질캅셀 - 새창
|
한미약품 |
Phenylpropanol | 일반의약품 | 비급여 |
|
|
로즈카캅셀 - 새창
|
아주약품공업 |
Phenylpropanolamine HCl S.R. 56% | 일반의약품 | 삭제 |
| phenylalanine |
an essential amino acid found in proteins and needed for growth of children and for protein metabolism in children and adults; abundant in milk and eggs; it is normally converted to tyrosine in the human body
출처: wordnet.princeton.edu/perl/webwn
|
|---|---|
| phenylamine |
aniline: oily poisonous liquid amine obtained from nitrobenzene and used to make dyes and plastics and medicines
출처: wordnet.princeton.edu/perl/webwn
|
| phenylbutazone |
anti-inflammatory drug (trade name Butazolidin)
출처: wordnet.princeton.edu/perl/webwn
|
| phenylketonuria |
a genetic disorder of metabolism; lack of the enzyme needed to turn phenylalanine into tyrosine results in an accumulation of phenylalanine in the body fluids which causes various degrees of mental deficiency
출처: wordnet.princeton.edu/perl/webwn
|
| phenyl salicylate |
salol: a white powder with a pleasant taste and odor; used to absorb light in sun tan lotions or as a preservative or an antiseptic or a coating for pills in which the medicine is intended for enteric release
출처: wordnet.princeton.edu/perl/webwn
|
| phenyl | a white powder with a pleasant taste and odor |
|---|---|
| phenyl | a white crystalline compound used as an analgesic and also as an antipyretic |
| phenyl | an essential amino acid found in proteins and needed for growth of children and for protein metabolism in children and adults |
| phenyl | oily poisonous liquid amine obtained from nitrobenzene and used to make dyes and plastics and medicines |
| phenyl | anti-inflammatory drug (trade name Butazolidin) |
| phenyl | a powerful vasoconstrictor used to dilate the pupils and relieve nasal congestion |
| phenyl | a colorless oily liquid |
| phenyl | a toxic white soluble crystalline acidic derivative of benzene |
| phenyl | a genetic disorder of metabolism |
| phenyl | an adrenergic drug used in many preparations to relieve allergic reactions or respiratory infections |
| phenyl | antihistamine included in some preparations used to treat coughing and nasal congestion |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
