| 영문 | toxin | 한글 | 독소 |
|---|---|---|---|
| 설명 | 생물체가 만들어내는 독성과 항원성을 가진 물질. 독소를 적당한 동물에 주사하면 항체인 항독소가 생성되고, 이 항독소와 독소는 특이적으로 결합한다. 세균에 의한 단백분해산물로 맹독성을 발휘나는 것에 아민이 있으나, 이것에는 항원성이 없으므로 독소가 아니다. 일반적으로 중독증상을 발현하는데 일정한 시간이 걸리며, 동물에 따라 감수성이 다른 점이 독물과 다르다. 독소에는 생물체 안에 만들어져 남아 있다가 생물체가 파괴되었을 때 독성을 갖는 내독소(endotoxins)와 생물체가 주변으로 물질을 분비하는 외독소(exotoxins)가 있다. 독소를 내는 생물체에 따라 세균성 독소 외에 동물성 독소 및 식물성 독소가 있다. 동물성 독소는 대부분 독선에서 분비되며, 뱀-전갈-거미-벌 등이 대표적인 것이다. 식물성 독소로는 리신(ricin)-아브린(abrin)-로비닌(robinin)-크로틴(crotin) 등이 있다. 세균은 인체에 영향을 미쳐 디프테리아-파상풍-성홍열-가스괴저 등을 일으키고, 또 어떤 세균과 버섯류는 생장할 때 독소를 분비, 이것을 먹으면 보툴리누스 중독-맥각 중독 등을 일으킨다. 그 밖에 물고기에도 독성을 가진 것이 있다. 인체에는 독소가 들어왔을 때 그와 결합하여 독성을 해독시키는 항독소가 혈청-림프액 등에 생긴다. |
||
| 영문 | whooping cough, pertussis | 한글 | 백일해 |
|---|---|---|---|
| 설명 | 이것은 주로 소아에서 백일해 균에 의해서 발생하는 상기도(위쪽의 기도를 말함. 즉 인두, 후두, 기관을 말함)감염증이다. 특징적인 갑작스런 큰 기침이 증상으로 나타난다. 치료는 항생제의 투여이며, 때로는 폐렴으로 발전하기도 한다. 현재 우리나라에서는 백일해에 대한 예방접종을 디프테리아(diphteria), 파상풍(tetanus)과 같이 실시하고 있다. |
||
| TAT | 1) Thematic Apperception Test; 주제 통각 검사 2) (Equine) Tetanus Anti-Toxin; 항... |
|---|---|
| CT | calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ... |
| ET | educational therapy; effective temperature; ejection time; embryo transfer; endothelin; endotoxin; e... |
| DPT | Diphtheria-Pertussis-Tetanus; 디프테리아, 백일해, 파상풍 |
| DTP | Diphtheria, Tetanus, Pertussis 디프테리아, 파상풍, 백일해 혼합 백신 |
| PT | Pertussis Toxin |
|---|---|
| PTX | Pertussis Toxin |
| BPV | Bordatella pertussis vaccine |
| B.p. | Bordetella pertussis |
| DPT | Diphtheria Pertussis Tetanus |
| pertussis toxin | <protein> Protein complex (ca 117 kD). An A B toxin, the active subunit is a single polypeptide 28 kD), the binding subunit a pentamer (two heterodimers, 23 + 11.7 kD, 11.7 + 22 kD and a monomer (9.3 kD) that binds the heterodimers). The active subunit ADP ribosylates the _ subunit of the inhibitory GTP-binding protein (Gi). Crucial to the pathogenicity of Bordetella pertussis, the causative agent of whooping cough. (18 Nov 1997) |
|---|---|
| pertussis toxins | <chemical> Any of various biologically active proteins or toxins elaborated by bordetella pertussis that cause the symptoms of whooping cough. Some activate pancreatic islets, others inhibit the adenylate cyclase cascade and some cause lymphocytosis. Chemical name: Toxins, pertussis (12 Dec 1998) |
| Bordetella pertussis | <bacteria> A small, aerobic, gram-negative bacillus, causative organism of whooping cough. Produces a variety of toxins including a dermonecrotising toxin, an adenyl cyclase, an endotoxin and pertussis toxin, as well as surface components such as fimbrial haemagglutinin. (18 Nov 1997) |
|---|---|
| pertussis | <infectious disease> An acute, highly contagious infection of the respiratory tract, most frequently affecting young children, usually caused by Bordetella pertussis, a similar illness has been associated with infection by B. Parapertussis and B. Bronchiseptica. It is characterised by a catarrhal stage, beginning after an incubation period of about two weeks, with slight fever, sneesing, running at the nose and a dry cough. In a week or two the paroxysmal stage begins, with the characteristic paroxysmal cough, consisting of a deep inspiration, followed by a series of quick, short coughs, continuing until the air is expelled from the lungs, the close of the paroxysm is marked by a long drawn, shrill, whooping inspiration, due to spasmodic closure of the glottis. This stage lasts three to four weeks, after which the convalescent stage begins, in which paroxysms grow less frequent and less violent and finally cease. Synonym: whooping cough. Origin: L. Tussis = cough (18 Nov 1997) |
| pertussis immune globulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
| pertussis immunoglobulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
| pertussis-like syndrome | <syndrome> A syndrome characterised by severe episodes of coughing resembling whooping cough (pertussis). (05 Mar 2000) |
| pertussis syndrome | <infectious disease> An acute, highly contagious infection of the respiratory tract, most frequently affecting young children, usually caused by Bordetella pertussis, a similar illness has been associated with infection by B. Parapertussis and B. Bronchiseptica. It is characterised by a catarrhal stage, beginning after an incubation period of about two weeks, with slight fever, sneesing, running at the nose and a dry cough. In a week or two the paroxysmal stage begins, with the characteristic paroxysmal cough, consisting of a deep inspiration, followed by a series of quick, short coughs, continuing until the air is expelled from the lungs, the close of the paroxysm is marked by a long drawn, shrill, whooping inspiration, due to spasmodic closure of the glottis. This stage lasts three to four weeks, after which the convalescent stage begins, in which paroxysms grow less frequent and less violent and finally cease. Synonym: whooping cough. Origin: L. Tussis = cough (18 Nov 1997) |
| pertussis vaccine | A suspension of killed bordetella pertussis organisms, used for immunization against pertussis (whooping cough). It is generally used in a mixture with diphtheria and tetanus toxoids (dtp). There is an acellular pertussis vaccine prepared from the purified antigenic components of bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (12 Dec 1998) |
| human pertussis immune serum | The sterile serum prepared from the pooled blood of healthy adult human beings who have received repeated courses of phase I pertussis vaccine; administered intravenously or intramuscularly for the prophylaxis or treatment of whooping cough. (05 Mar 2000) |
| diphtheria-tetanus-pertussis vaccine | A vaccine consisting of diphtheria toxoid, tetanus toxoid, and pertussis vaccine. It is usually given to infants three times at two-month intervals, generally at 2, 4, and 6 months of age. The vaccine protects against diphtheria, tetanus, and whooping cough. In most cases the vaccine causes only a temporary fever and discomfort, but in a few cases serious neurological side effects have been observed. (12 Dec 1998) |
| animal toxin | <pharmacology> Any poisonous substance (including but not limited to venom) produced by an animal. (11 May 1997) |
| anthrax toxin | A culture filtrate of Bacillus anthracis containing an exotoxin with at least three different antigenically distinct components: oedema factor, lethal factor, and protective antigen. Synonym: Bacillus anthracis toxin. (05 Mar 2000) |
| Bacillus anthracis toxin | A culture filtrate of Bacillus anthracis containing an exotoxin with at least three different antigenically distinct components: oedema factor, lethal factor, and protective antigen. Synonym: Bacillus anthracis toxin. (05 Mar 2000) |
| bacterial toxin | Any intracellular or extracellular toxin formed in or elaborated by bacterial cells. (05 Mar 2000) |
| bee toxin | The toxin delivered by a bee sting; contains three active principles: biogenic amines, active peptides, and certain hydrolytic enzymes. (05 Mar 2000) |
| botulinum toxin | <protein> Neurotoxin (50 kD, 7 distinct serotypes) produced by certain strains of Clostridium botulinum. The bacterium produces the toxin as a complex with a haemagglutinin that prevents toxin inactivation in the gut. Proteolysis in the body results in cleavage into two fragments A and B. B binds to gangliosides and may stimulate the endocytosis of fragment A. See: synaptobrevin, tetanus toxin. (18 Nov 1997) |
Synonyms : Histamine-Sensitizing Factor, Islets-Activating Protein, Lymphocytosis-Promoting Factor, Histamine Sensitizing Factor, Islet Activating Protein, Islets Activating Protein, Lymphocytosis Promoting Factor, Pertussis Toxin, IAP, Toxin, IAP Pertussis
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|