| ¿µ¹® | peptide | ÇÑ±Û | ÆéƼµå |
|---|---|---|---|
| ¼³¸í | µÎ °³ÀÌ»óÀÇ ¾Æ¹Ì³ë»ê ºÐÀÚ »çÀÌ¿¡¼, ÇÑÂÊÀÇ ¾Æ¹Ì³ë±â¿Í ´Ù¸¥ ÂÊÀÇ Ä«¸£º¹½Ç±â°¡ ¹° ºÐÀÚ¸¦ ÀÒÀ¸¸é¼ ÃàÇÕÇÏ¿© ÀÌ·ç´Â ¾Æ¹Ìµå °áÇվƹ̳ë»êÀÇ ¼ö°¡ 2, 3, ¡¦ ÀÎ °æ¿ì, °¢°¢ µðÆéƼµå, Æ®¸®ÆéƼµå, ¡¦µîÀ¸·Î ºÎ¸£¸ç, ¿©·¯ °³ÀÇ ¾Æ¹Ì³ë»êÀ¸·Î ±¸¼ºµÇ´Â °ÍÀ» ¿Ã¸®°íÆéƼµå, À̺¸´Ù Å« °ÍÀ» Æú¸®ÆéƼµå¶ó°í ÇÑ´Ù. Á÷¼â»óÀÇ °ÍÀÌ ¸¹Áö¸¸, ȯ»ó ±¸Á¶¸¦ °®´Â ÆéƼµåµµ ÀÖ´Ù. ÀúºÐÀÚÀÇ ÆéƼµå´Â ¹°, »ê, ¾ËÄ®¸® µûÀ§¿¡ Àß ³ì°í ¾ËÄڿÿ¡´Â ³ìÁö ¾ÊÀ¸³ª, °íºÐÀÚÀÇ ÆéƼµå´Â ¹°¿¡ Àß ³ìÁö ¾Ê°í ´Ü¹éÁú°ú ¼ºÁúÀÌ ºñ½ÁÇÏ´Ù. ³úÇϼöüȣ¸£¸ó, ºê¶óµðŰ´Ñ µî°ú °°ÀÌ »ý¸®Àû±â´ÉÀÌ ÇöÀúÇÑ °ÍÀº »ý¸®È°¼ºÆéƼµå(bioactive peptide)¶ó°í ÇÑ´Ù. |
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| ¿µ¹® | thyroid hormone | ÇÑ±Û | °©»ó»ùÈ£¸£¸ó |
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| ¼³¸í | ±¤ÀÇÀÇ °©»ó¼±È£¸£¸óÀº Ƽ·Ï½Å(thyroxine(T4)), »ï¿äµåƼ·Î´Ñ(triiodothyronine (T3)), Ƽ·ÎÄ®½ÃÅä´Ñ(thyrocalcitonin)ÀÇ 3°¡ÁöÁß Çϳª¸¦ ¸»Çϳª ´ë°³ÀÇ °æ¿ì ÇùÀÇÀÇ ¶æÀ¸·Î »ç¿ëµÇ¸ç ÀÌ °æ¿ì Ƽ·Ï½Å°ú »ï¿äµåƼ·Î´ÑÀ» ÁöĪÇÑ´Ù. °©»ó¼± È£¸£¸óÀº °ÅÀÇ ¸ðµç ¸ö¼¼Æ÷¿¡¼ÀÇ ¹ÙÅÁÁú´ë»ç¿¡ °ü¿©ÇÏ¿© ¿¡³ÊÁö»ý¼ºÀ» Áõ°¡½ÃŰ°í ¼ºÀå ¹ßÀ°À» ÃËÁøÇÑ´Ù. À̰ÍÀº ³úÇϼöü¿¡¼ ºÐºñµÇ´Â °©»ó»ù ÀÚ±ØÈ£¸£¸ó¿¡ ÀÇÇØ ÇÕ¼º ¹× ºÐºñ°¡ ÃËÁøµÈ´Ù. ¼·ÃëÇÏ¿© ü³»¿¡ µé¾î¿Â ¿ä¿Àµå°¡ ´Éµ¿¿î¹Ý¿¡ ÀÇÇØ °©»ó»ù¼¼Æ÷³»·Î µé¾î°¡ ¼¼Æ÷³»¿¡ ÀÖ´Â ´Ü¹éÁúÀÎ °©»ó»ù ±Û·Îºí¸°°ú °áÇÕÇÏ¿© °©»ó»ùÈ£¸£¸óÀ¸·Î ÇÕ¼ºµÈ´Ù. ¿ä¿Àµå°¡ 3ºÐÀÚ °áÇÕÇÑ °ÍÀ» T3, 4ºÐÀÚ °áÇÕÇÑ °ÍÀ» T4¶ó ºÎ¸§. ºÐºñµÇ´Â °©»ó¼± È£¸£¸óÁß 90%ÀÌ»óÀÌ T4ÀÌ´Ù. Ç÷ÁßÀ¸·Î ºÐºñµÈ °©»ó»ùÈ£¸£¸óÀº Ç÷Áß ´Ü¹éÁú°ú °áÇÕÇϴµ¥ ´ëºÎºÐÀº Ƽ·Ð½Å°áÇÕ±Û·Îºí¸°°ú °áÇÕÇϸç ÀϺδ ¾ËºÎ¹Î°ú °áÇÕÇÑ´Ù. Àü¹ÝÀûÀÎ ´ë»çÀ²À» ÃËÁø½ÃŰ¸ç ¾î¸°ÀÌ¿¡¼´Â ¼ºÀåÀ» ÃËÁø½ÃŲ´Ù. ƯÈ÷ ¾î¸°ÀÌ¿¡¼ ¸ô´Ü¹éÁú ÇÕ¼ºÀ» ÃËÁøÇÏ¸ç ³úÀÇ ¹ß´Þ¿¡ Áß¿äÇÑ ±â´ÉÀ» ÇÔÀ¸·Î½á, ¼±Ãµ¼º °©»ó»ùÀúÇÏÁõ(cretinism)À» Á¶±â ¹ß°ßÇÏ¿© Ä¡·áÇÏÁö ¸øÇϸé Á¤½ÅÁöü°¡ À¯¹ßµÈ´Ù. °©»ó»ù°ú´ÙÁõÀÇ Áõ»óÀº ü³» ´ë»ç°¡ Ç×ÁøµÇ¾î ½Ä¿åÀÌ Áõ°¡Çϳª üÁßÀÌ °¨¼ÒÇÏ°í ½ÉÀå¹Úµ¿¼ö°¡ Áõ°¡ÇÏ°í ´õÀ§¸¦ ÂüÁö ¸øÇϸç, °©»ó»ù±â´ÉÀúÇÏÁõÀÇ Áõ»óÀº À§¿Í ¹Ý´ë·Î ½Ä¿åÀÌ °¨¼ÒÇϰí üÁßÀÌ Áõ°¡ÇÏ¸ç ½ÉÀå¹Úµ¿¼ö°¡ °¨¼ÒÇϰí ÃßÀ§¸¦ ÂüÁö ¸øÇϸç ÇǺο¡ ´Ü¹éÁúÀÌ ÃàÀûµÇ¾î Á¡¾×ºÎÁ¾ÀÌ À¯¹ßµÈ´Ù. |
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| ¿µ¹® | adrenocorticotropic hormone | ÇÑ±Û | ºÎ½Å°ÑÁúÀÚ±ØÈ£¸£¸ó |
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| ¼³¸í | ³úÇϼöü Àü¿±¿¡¼ ºÐºñµÇ¾î ºÎ½Å°ÑÁúÀ» ÀÚ±ØÇÏ´Â ´Ü¹é¼º È£¸£¸ó. ÇϼöüÀü¿°¿¡¼ ¸¸µé¾îÁ® ºÐºñµÇ´Â È£¸£¸óÀÌ´Ù. ºÎ½Å°ÑÁúÀÚ±Ø ÀÛ¿ëÀÌ ÀÖÀ¸¸ç ºÎ½Å°ÑÁúÁú¼¼Æ÷ÀÇ °æ¿ì¿¡ ½ºÅ×·ÎÀ̵åÈ£¸£¸ó »ýÇÕ¼ºÀÇ Á¶Àý´Ü°èÀÎ ÄÝ·¹½ºÅ׷ѷκÎÅÍÀÇ ÇÁ·¹±×³×·Ñ·Ð»ý¼ºÀ» ÃËÁøÇÑ´Ù. °áÁ¤±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵忡 ÀÇÇØ ¹Ý´ëÀÇ µÇ¸ÔÀÓÁ¶Á¤À» ¹Þ´Â´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵åÀÇ ÇϼöüÀü¿±¿¡ ´ëÇÑ Á÷Á¢ÀÛ¿ë°ú ½Ã»óÇϺÎÀÇ ºÎ½Å°ÑÁúÀÚ±ØÈ£¸£¸ó ¹æÃâÈ£¸£¸óÀ» ¸Åü·Î ÇÑ °£Á¢ÀÛ¿ëÀÌ ÀÖ´Ù. ¿©·¯ Á¾·ùÀÇ Á¤½ÅÀû À°Ã¼Àû ½ºÆ®·¹½º¿¡ ÀÇÇØ ºÐºñ°¡ ÀڱصȴÙ. |
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| ¿µ¹® | growth hormone | ÇÑ±Û | ¼ºÀåÈ£¸£¸ó |
|---|---|---|---|
| ¼³¸í | ³úÇϼöü Àü¿±¿¡¼ ºÐºñµÇ´Â È£¸£¸óÁß Çϳª·Î¼ ½Ã»óÇϺÎÀÇ ¼ºÀåÈ£¸£¸ó¹æÃâ È£¸£¸ó¿¡ ÀÇÇØ ºÐºñ°¡ ÀÚ±ØµÇ¸ç ¼Ò¸¶Å佺Ÿƾ(somatostatin: ÀÌÀÚ¿¡¼ ºÐºñµÇ¸ç, ¼ºÀåÈ£¸£¸ó¿¡ ¹Ý´ëµÇ´Â ÀÛ¿ëÀ» ÇÔ)¿¡ ÀÇÇØ ºÐºñ°¡ ¾ïÁ¦µÈ´Ù. ¼ºÀå È£¸£¸ó ¹æÃâ È£¸£¸óÀº µµÆÄ¹Î(dopamine)À¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. ¼ºÀå È£¸£¸óÀº ¼¼Æ÷ÀÇ ¼ºÀåÀ» ÃËÁø½Ã۸ç ƯÈ÷ °ñÀÇ ¼ºÀåÀ» ÀÚ±ØÇϴµ¥ ±× ÀÛ¿ëÀº Á÷Á¢ ¼¼Æ÷¿¡ ÀÛ¿ëÇÏ´Â °ÍÀÌ ¾Æ´Ï¶ó °£°ú ±ÙÀ°¿¡ ÀÛ¿ëÇÏ¿© ±×°÷¿¡¼ ¼Ò¸¶Åä¸ÞµòÀ» »ý¼ºÇϸç ÀÌ ¼Ò¸¶Åä¸ÞµòÀÌ ¼¼Æ÷ÀÇ ¼ºÀåÀ» ÃËÁø½ÃŲ´Ù. ÇÑÆí ¼ºÀå È£¸£¸óÀº ¼ºÀå¿¡ ÇÊ¿äÇÑ ´Ü¹éÁú ÇÕ¼ºÀ» Ç×Áø½ÃŰ°í ¿¡³ÊÁö´Â Áö¹æÀ» ÀÌ¿ëÇÏ¿© ¾ò°ÔÇϹǷΠÁö¹æÀÌ¿ëÈ£¸£¸óÀ̶ó°íµµ ºÒ¸°´Ù. ¼ºÀå È£¸£¸óÀÌ °ú´Ù ºÐºñµÇ¸é °ÅÀÎÁõ, ¸»´Üºñ´ëÁõÀÌ À¯¹ßµÇ¸ç ¼ºÀå È£¸£¸óÀÌ °áÇÌµÇ¸é ¼ºÀåºÎÁøÀÌ ¿Â´Ù. |
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| BBEP | brush border endopeptidase |
|---|---|
| IAD | inactivating dose; instructional advance directive; internal absorbed dose |
| NEP | negative expiratory pressure; nephrology; neutral endopeptidase; no evidence of pathology |
| VIA | virus inactivating agent; virus infection-associated antigen |
| PTHRP, PTHrP | parathyroid-hormone-related peptide; parathyroid-hormone-related protein |
| RIP | Ribosome Inactivating Protein |
|---|---|
| NEP | Neutral Endopeptidase |
| PEP | Prolyl endopeptidase |
| PTH/PTHrP | Parathyroid hormone/parathyroid-hormone-related peptide |
| C-peptide | connecting peptide |
corticotropin-releasing factor (ºÎ½Å ÇÇÁú È£¸£¸ó À¯¸® ¿ä¼Ò, ºÎ½Å ÇÇÁú È£¸£¸ó À¯¸® ÀÎÀÚ
| peptide hormone inactivating endopeptidase | <enzyme> From xenopus laevis; cleaves at xaa-phe, xaa-leu or xaa-ile bonds where xaa = ser, phe, tyr, his or gly in peptide hormones Registry number: EC 3.4.24.- Synonym: phie, xenopus (26 Jun 1999) |
|---|
| receptors, pituitary hormone-regulating hormone | Cell surface receptors that bind the hypothalamic hormones regulating pituitary cell differentiation, proliferation, and hormone synthesis and release, including the pituitary-releasing and release-inhibiting hormones. The pituitary hormone-regulating hormones are also released by cells other than hypothalamic neurons, and their receptors also occur on non-pituitary cells, especially brain neurons, where their role is less well understood. Receptors for dopamine, which is a prolactin release-inhibiting hormone as well as a common neurotransmitter, are not included here. (12 Dec 1998) |
|---|---|
| growth hormone inhibiting hormone | <protein> Gastrointestinal and hypothalmic peptide hormone (two forms: 14 and 28 residues), found in gastric mucosa, pancreatic islets, nerves of the gastrointestinal tract, in posterior pituitary and in the central nervous system. Inhibits gastric secretion and motility: in hypothalamus/pituitary inhibits somatotropin release. (18 Nov 1997) |
| growth hormone-regulating hormone | <endocrinology> Hypothalamic hormones that induce (somatoliberin) or inhibit (somatostatin) the release of growth hormone (somatotropin). (18 Nov 1997) |
| growth hormone-releasing hormone | <endocrinology> Peptide hormone related to the glucagon family, released from the pituitary, acts on the adenohypophysis to release growth hormone. Synonym: somatoliberin, growth hormone-releasing factor. (20 Sep 2002) |
| hormones, hormone substitutes, and hormone antagonists | A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. (12 Dec 1998) |
| follicle-stimulating hormone-releasing hormone | A decapeptide of hypothalamic origin capable of accelerating pituitary secretion of follitropin. Synonym: follicle-stimulating hormone-releasing factor, follicle-stimulating hormone-releasing hormone. Origin: follicle-stimulating hormone + L. Libero, to free, + -in (05 Mar 2000) |
| luteinizing hormone/follicle-stimulating hormone-releasing factor | gonadotrophin-releasing hormone |
| luteinizing hormone-releasing hormone | A hormone that controls sex hormones in men and women. Also called lhrh. (12 Dec 1998) |
| adenovirus endopeptidase | <enzyme> Has been sequenced; high homology for enzymes from human, bovine, canine, murine and avian adenoviruses; see also record for avian adenovirus type 1 proteinase Registry number: EC 3.4.22.- Synonym: ad2 proteinase, can1 proteinase, mav1 proteinase, adenovirus proteinase ad2 (26 Jun 1999) |
| alanine endopeptidase | <enzyme> From enterocyte brush border; cleaves between alanyl and alanyl-, leucyl-, or norleucyl- residues of synthetic peptides similar to metallic endopeptidases Registry number: EC 3.4.24.- (26 Jun 1999) |
| arginine endopeptidase | <enzyme> Cleaves arginine at the carboxyl side in a peptide chain Registry number: EC 3.4.21.- Synonym: arginyl endopeptidase (26 Jun 1999) |
| glutamyl endopeptidase | <enzyme> Cleaves at the carboxyl side of glutamate and aspartate residues in proteins; see also glutamyl endopeptidase II from strep. Griseus (EC 3.4.21.82) Registry number: EC 3.4.21.19 Synonym: staphylococcus v-8 protease, v-8 protease, protease v8, staph aureus sv8 protease, staphylococcal serine protease, glu-c protease, staphylococcal glu-c protease, endoproteinase glu-c, protease glu-c, glutamate-specific endopeptidase, endopeptidase glu-c (26 Jun 1999) |
| glycyl endopeptidase | <enzyme> Isoelectric pt greater than 11.1; molecular mass=24k; separable from papaya proteinase a by acid gel electrophoresis; from papaya plant carcica papaya; not inhibited by chicken cystatin Registry number: EC 3.4.22.25 Synonym: papaya peptidase b, papaya proteinase b, papaya proteinase iv (26 Jun 1999) |
| PepE endopeptidase | <enzyme> Thiol-dependent endoprotease from lactobacillus helveticus; do not confuse with pepe protein, which is an aspartic proteinase from aspergillus niger; genbank u77050 Registry number: EC 3.4.- Synonym: pepe gene product, lactobacillus (26 Jun 1999) |
| procollagen C-endopeptidase | <enzyme> Cleaves the carboxyl-terminal propeptides from type I pr; in 1996 determined to be identical to bone morphogenetic protein 1 Registry number: EC 3.4.24.19 Synonym: procollagen c-protease, type I procollagen carboxyl-terminal proteinase, c-proteinase, procollagen, procollagen endopeptidase (carboxy terminal splitting), procollagen c-proteinase, bone morphogenetic protein 1, bone morphogenic protein 1, bmp-1 (26 Jun 1999) |
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