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AAA abdominal aortic aneurysm/aneurysmectomy; acne-associated arthritis; acquired aplastic anemia; acute...
AAAI American Academy of Allergy and Immunology
AACIA American Association for Clinical Immunology and Allergy
ACAAI American College of Allergy, Asthma and Immunology
AI accidental injury; accidentally incurred; adiposity index; aggregation index; allergy and immunology...
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penicillin V phenoxymethyl-penicillin
CMA Cow's milk allergy
F.A. Food Allergy
LAA Laboratory Animal Allergy
NIAID National Institute of Allergy and Infectious Disease
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allergy 1. <immunology> A state of hypersensitivity induced by exposure to a particular antigen (allergen) resulting in harmful immunologic reactions on subsequent exposures, the term is usually used to refer to hypersensitivity to an environmental antigen (atopic allergy or contact dermatitis) or to drug allergy.
The original meaning, now obsolete, included all states of altered immunologic reactivity, immunity as well as hypersensitivity. Gell and Coombs used the term allergic reaction to mean any harmful immunologic reaction causing tissue injury.
2. <study> The medical specialty dealing with diagnosis and treatment of allergic disorders.
(18 Nov 1997)
allergy and immunology A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder.
(12 Dec 1998)
allergy desensitization Stimulation of the immune system with gradually increasing doses of the substances to which a person is allergic, the aim being to modify or stop the allergy war (by reducing the strength of the IgE and its effect on the mast cells). This form of treatment is very effective for allergies to pollen, mites, cats, and especially stinging insects (e.g., bees, hornets, yellowjackets, wasps, velvet ants, fire ants). Allergy immunotherapy usually takes 6 months to a year to become effective and injections ( shots ) are usually required for 3-5 years.
(12 Dec 1998)
allergy shots See Allergy desensitization.
(12 Dec 1998)
allergy skin test Test done on the skin to identify the allergy substance (allergen) triggering the allergic reaction. A small amount of the suspected allergy substance is placed on the skin. The skin is then gently scratched through the small drop with a special sterile needle. If the skin reddens and, more importantly, swells, then allergy to that substance is probable.
(12 Dec 1998)
allergy testing <investigation> A common method of screening a patient for potential allergies. May be given as a patch or a skin test (injection).
(27 Sep 1997)
aluminum penicillin The trivalent aluminum salt of an antibiotic substance or substances produced by the growth of the molds Penicillium notatum or P. Chrysogenum; used for oral or sublingual administration.
(05 Mar 2000)
atopic allergy <immunology> An allergic reaction with strong family tendencies.
(09 Oct 1997)
bacterial allergy The concept that the atopic kind of type I allergic reactions may be caused by bacterial allergens, the delayed type of skin test, so-called because of its early association with bacterial antigens (e.g., the tuberculin test).
(05 Mar 2000)
benzyl penicillin <chemical> (2s-(2 alpha,5 alpha,6 beta))-3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid. A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on gaba mediated synaptic transmission.
Pharmacological action: convulsants, gaba modulators, penicillins.
Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)- (2S-(2alpha,5alpha,6beta))-
(12 Dec 1998)
buffered crystalline penicillin G Crystalline potassium penicillin G or crystalline sodium penicillin G buffered with not less than 4% and not more than 5% of sodium citrate.
(05 Mar 2000)
penicillin <drug> Probably the best known of the antibiotics, derived from the mould Penicillium notatum. It blocks the cross linking reaction in peptidoglycan synthesis and therefore destroys the bacterial cell wall making the bacterium very susceptible to damage.
(18 Nov 1997)
penicillin amidase <enzyme> An enzyme catalyzing the hydrolysis of penicillin to penicin and a carboxylic acid anion.
Chemical name: Penicillin amidohydrolase
Registry number: EC 3.5.1.11
(12 Dec 1998)
penicillin B A penicillin preparation that is stable in gastric acid and is rapidly but only partially absorbed from the gastrointestinal tract.
Synonym: alpha-phenoxyethylpenicillin potassium, penicillin B.
(05 Mar 2000)
penicillin G <chemical> (2s-(2 alpha,5 alpha,6 beta))-3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid. A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on gaba mediated synaptic transmission.
Pharmacological action: convulsants, gaba modulators, penicillins.
Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)- (2S-(2alpha,5alpha,6beta))-
(12 Dec 1998)
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penicillin allergy A hypersensitivity reaction to penicillin, present in about 0.5% to 8% of the population. Although different types of hypersensitivity reactions may occur, the most common and potentially dangerous are the type I (immediate) r
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