| 영문 | systemic lupus erythematosus | 한글 | 전신홍반루푸스 |
|---|---|---|---|
| 설명 | 전신 자가면역병의 대표적 병이다. 여성에게 압도적으로 많고, 10~39세까지가 70%를 차지한다. 원인은 잘 모르나 자가면역 조절기능에 장애가 있는 것으로 생각된다. 유전요인, 호르몬의 영향, 환경요소가 종합적으로 보조 T세포와 B세포를 활성화시켜서 여러 가지 자가항체들, 즉 천연 DNA, 이중가닥 DNA, 외가닥 DNA, RNA, 핵단백질 등과 같은 핵 항원에 대한 항체, 비핵항원에 대한 여러 가지 항체가 쏟아져 나온다. 이 중 이중가닥 DNA를 포함한 순환면역복합체가 콩팥에 침착하여 손상을 일으키는데 관여한다. DNA와 여러 가지 세포성분에 대한 자가면역질환으로 전콩팥기를 침범하여 염증을 일으킨다. 여러 자가항원에 대한 면역반응에 의한 항체의존성 면역반응과 면역복합체 반응으로 토리콩팥염, 혈관염, 관절염 및 빈혈을 동반한다. |
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| 영문 | pemphigus | 한글 | 천포창 |
|---|---|---|---|
| 설명 | 원인을 알 수 없는 자가면역병(자신의 세포를 항원으로 하여 항체를 형성하고 이로 인한 염증반응과 항원-항체반응을 주원인으로 하는 병: 정상적으로 자신에 대해서는 항체를 형성하지 않는다)으로 피부와 점막에 많은 물집을 생성한다. 특징적으로 Nikolsky증후(병터가 있는 피부를 손으로 밀면, 그 부위를 덮고 있는 피부가 벗겨진다)가 나타나며, 보다 정확한 진단은 면역형광법을 시행하므로서 가능하다. 성인에게 잘 발생하는데 대개 물집이 발생한 뒤, 저절로 소실되고, 병변이 있던 리에 색깔이 있는 반점을 형성한다. 심한 경우는 그 부위를 통한 감염이 자주 발생하기도 한다. 치료는 대증적 치료와 면역억제제(주로 corticosteroid)의 투여이다. |
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| DLE | delayed light emission; dialyzable leukocyte extract; discoid lupus erythematosus; disseminated lupu... |
|---|---|
| PF | 1) Platelet Factor 2) Pemphigus Foliaceus |
| BMPP | benign mucous membrane pemphigus |
| BP | Bachelor of Pharmacy; back pressure; barometric pressure; basic protein; bathroom privileges; bed pa... |
| CBMMP | chronic benign mucous membrane pemphigus |
| PNP | Paraneoplastic pemphigus |
|---|---|
| PF | Pemphigus foliaceus |
| PV | Pemphigus vulgaris |
| DLE | Discoid Lupus Erythematosus |
| LE | Lupus Erythematosus |
| pemphigus erythematosus | An eruption involving sun-exposed skin, especially the face; the lesions are scaling erythematous macules and blebs, combining the clinical features of both lupus erythematosus and pemphigus vulgaris; bullae are subcorneal; probably a variant of pemphigus foliaceus. Synonym: Senear-Usher disease, Senear-Usher syndrome. (05 Mar 2000) |
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| benign familial chronic pemphigus | Recurrent eruption of vesicles and bullae that become scaling and crusted lesions with vesicular borders, predominantly of the neck, groin, and axillary regions; autosomal dominant inheritance, presenting in late adolescence or early adult life. Synonym: Hailey-Hailey disease. (05 Mar 2000) |
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| Brazilian pemphigus | A form of pemphigus foliaceus, occurring in southern Brazil, in which the lesions are bullous, appear localised to the face and upper trunk, become widespread, variegated, erythrodermic, and exfoliative, and are immunologically indistinguishable from pemphigus foliaceus or vulgaris. Synonym: Brazilian pemphigus, wildfire. Origin: Pg. Wild fire (05 Mar 2000) |
| pemphigus | <dermatology> A group of chronic, relapsing, sometimes fatal skin diseases characterised clinically by the development of successive crops of vesicles and bullae, histologically by acantholysis and immunologically by serum autoantibodies directed against antigens in the intracellular zones of the epidermis. The specific disease is usually indicated by a modifying term, but the term pemphigus is often used alone to designate pemphigus vulgaris. Origin: Gr. Pemphix = blister (18 Nov 1997) |
| pemphigus acutus | An obsolete term for a pyogenic infection due to local trauma, that responds to antibiotic therapy; if untreated, the condition may become extensive and the patient seriously ill. Synonym: bullous fever. (05 Mar 2000) |
| pemphigus, benign familial | Rare hereditary disease characterised by recurrent eruptions of vesicles and bullae mainly on the neck, axillae, and groin. It exhibits autosomal dominant inheritance and is unrelated to pemphigus vulgaris though it closely resembles that disease. (12 Dec 1998) |
| pemphigus contagiosus | An obsolete term for a superficial pyogenic infection. Synonym: Manson's pyosis. (05 Mar 2000) |
| pemphigus foliaceus | A generally chronic form of pemphigus in which extensive exfoliative dermatitis, with no perceptible blistering, may be present in addition to the bullae; serum autoantibodies induce bullae and crusted acantholytic superficial epidermal lesions. (05 Mar 2000) |
| pemphigus gangrenosus | A bullous or pustular eruption, of uncertain origin, followed by necrotic ulcers or extensive gangrene in children under 2 years of age; if untreated, death may result from haematogenous infection, such as liver abscess. Synonym: disseminated cutaneous gangrene, ecthyma gangrenosum, pemphigus gangrenosus, rupia escharotica. (05 Mar 2000) |
| pemphigus leprosus | An eruption of bullae, occurring sometimes in the course of anaesthetic leprosy. (05 Mar 2000) |
| pemphigus vegetans | A form of pemphigus vulgaris in which vegetations develop on the eroded surfaces left by ruptured bullae; new bullae continue to form. Synonym: Neumann's disease. A chronic benign vegetating form of pemphigus, with lesions commonly in the axillae and perineum; spontaneous remissions and occasionally permanent healing occur. Synonym: Hallopeau's disease. (05 Mar 2000) |
| pemphigus vulgaris | A serious form of pemphigus, occurring in middle age, in which cutaneous flaccid acantholytic suprabasal bullae and oral mucosal erosions may be localised a few months before becoming generalised; blisters break easily and are slow to heal; results from the action of autoimmune antibodies that localise to intercellular sites of stratified squamous epithelium. (05 Mar 2000) |
| panniculitis, lupus erythematosus | A type of lupus erythematosus characterised by deep dermal or subcutaneous nodules, most often on the head, face, or upper arms. It is generally chronic and occurs most often in women between the ages of 20 and 45. (12 Dec 1998) |
| chilblain lupus erythematosus | Skin lesions seen in patients with lupus erythematosus, resembling the small, hardened nodular areas of a cold injury called chilblains. Synonym: chilblain lupus. (05 Mar 2000) |
| chronic discoid lupus erythematosus | A form of lupus erythematosus in which cutaneous lesions are present; these commonly appear on the face and are atrophic plaques with erythema, hyperkeratosis, follicular plugging, and telangiectasia; in some instances systemic lupus erythematosis may develop. Synonym: chronic discoid lupus erythematosus. (05 Mar 2000) |
| cutaneous lupus erythematosus | Skin disease seen in patients with discoid form of lupus erythematosus, a term for a variety of skin lesions seen in systemic lupus erythematosus. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|