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PCD pacer-cardioverter-defibrillator; papillary collecting duct; paraneoplastic cerebellar degeneration;...
PLE paraneoplastic limbic encephalopathy; protein-losing enteropathy; pseudolupus erythematosus
PNEM paraneoplastic encephalomyelitis
PNS paraneoplastic syndrome; parasympathetic nervous system; partial nonprogressive stroke; peripheral n...
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PCD Paraneoplastic cerebellar degeneration
PEM Paraneoplastic encephalomyelitis
PNP Paraneoplastic pemphigus
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paraneoplastic acrokeratosis <syndrome> Erythematous to plum-coloured scaly acral skin lesions, paronychia, and nail dysplasia; associated with cancer of the upper respiratory or upper alimentary tract.
Synonym: paraneoplastic acrokeratosis.
(05 Mar 2000)
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acrokeratosis Overgrowth of the horny layer of the skin, usually nodular configurations, of the dorsum of the fingers and toes, and occasionally on the rim of the ear and tip of the nose.
Origin: acro-+ G. Keras, horn, + -osis, condition
(05 Mar 2000)
acrokeratosis verruciformis <dermatology> Warty hyperkeratotic lesions that are found on the dorsal aspect of the hands and feet and on the knees and elbows.
There appears to be phenotypic overlap between this and Darier-White disease and they may not be separate entities.
Clinical features include: acrokeratosis, warty hyperkeratosis on the dorsal hands, feet, knees and elbows.
See: benign familial pemphigus.
Inheritance: autosomal dominant.
(05 Aug 1998)
paraneoplastic Relating to or characteristic of paraneoplasia.
(05 Mar 2000)
paraneoplastic encephalomyelopathy An encephalomyelopathy as a remote effect of carcinoma, most often oat cell carcinoma of the lung; characterised by extensive nerve cell loss, which may be diffuse, but often predominates in particular portions of the central nervous system, particularly the limbic lobes, medulla, cerebellum, and gray matter of the spinal cord.
Synonym: carcinomatous encephalomyelopathy, encephalomyelitis associated with carcinoma, paracarcinomatous encephalomyelopathy.
(05 Mar 2000)
paraneoplastic syndrome <oncology, syndrome> A collection of symptoms or clinical signs that are found in patients that have malignant disease. By definition, the signs and symptoms are not produced by a direct effect of a tumour or its metastasis nor due to direct invasion, compression, metastasis, infection, nutritional deficiency or treatment of the underlying neoplasm.
Paraneoplastic syndromes can arise from tumour produced biologically active polypeptides or proteins, autoimmunity or immune complex production and immune suppression, blockade of the normal effect of a hormone, the release of substances from tumour associated endothelium which are not normally released and finally unknown causes.
The best characterised paraneoplastic syndrome is the syndrome of inappropriate ADH.
(15 Dec 1997)
paraneoplastic syndromes In patients with neoplastic diseases a wide variety of clinical pictures which are indirect and usually remote effects produced by tumour cell metabolites or other products.
(12 Dec 1998)
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