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"oxygen derived free radicals"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
À̰ÍÀ» ¿øÇϼ̽À´Ï±î?
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¿µ¹® oxygen ÇÑ±Û »ê¼Ò
¼³¸í   
  Æó·Î µé¾î°¡ ¸ð¼¼Ç÷°üÀ» ÅëÇØ ÀûÇ÷±¸³»·Î µé¾î°£´Ù. ÀûÇ÷±¸³»ÀÇ Ç÷»ö¼ÒÀÇ ¿ªÇҷΠ½Åü³» ¸ðµç Á¶Á÷¼¼Æ÷¿¡ ÀüÇØÁö¸ç, ÀÎü´ë»çÀÛ¿ë¿¡ ÇʼöÀûÀΠ±âüÀÌ´Ù.
´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • bone marrow-derived cell
    °ñ¼öÀ¯·¡¼¼Æ÷
  • derived protein
    À¯µµ´Ü¹éÁú
  • endothelium-derived contracting factor
    ³»ÇÇÀ¯·¡¼öÃàÀÎÀÚ
  • endothelium-derived relaxing factor
    ³»ÇÇÀ¯·¡ÀÌ¿ÏÀÎÀÚ
  • macrophage-derived growth factor
    Å«Æ÷½Ä¼¼Æ÷À¯·¡¼ºÀåÀÎÀÚ, ´ë½Ä¼¼Æ÷À¯·¡¼ºÀåÀÎÀÚ
  • membrane-derived oligosaccharide
    ¼¼Æ÷¸·À¯·¡¼Ò´ç·ù, ¼¼Æ÷¸·À¯·¡¿Ã¸®°í´ç·ù
  • platelet-derived growth factor
    Ç÷¼ÒÆÇÀ¯·¡¼ºÀåÀÎÀÚ, Ç÷¼ÒÆÇ±â¿ø¼ºÀåÀÎÀÚ
  • arterial oxygen saturation
    µ¿¸ÆÇ÷»ê¼ÒÆ÷È­µµ
  • arterial oxygen tension
    µ¿¸ÆÇ÷»ê¼ÒºÐ¾Ð
  • active oxygen
    Ȱµ¿»ê¼Ò, Ȱ¼º»ê¼Ò
  • alveolar oxygen pressure
    ÆóÆ÷»ê¼Ò¾Ð, ÇãÆÄ²Ê¸®»ê¼Ò¾Ð
  • alveolar-arterial oxygen gradient
    ÆóÆ÷µ¿¸Æ°£»ê¼ÒºÐ¾ÐÂ÷
  • biochemical oxygen demand
    »ý¹°È­ÇÐÀû»ê¼Ò¿ä±¸·®
  • biological oxygen demand
    »ý¹°ÇÐÀû»ê¼Ò¿ä±¸·®
  • compressed oxygen
    ¾ÐÃà»ê¼Ò
´ëÇÑÀÇÇù Çʼö ÀÇÇпë¾îÁý »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • platelet-derived growth factor
    Ç÷¼ÒÆÇÀ¯·¡¼ºÀåÀÎÀÚ, Ç÷¼ÒÆÇ±â¿ø¼ºÀåÀÎÀÚ
  • free water clearance
    À¯¸®¼öºÐÁ¦°Å, À¯¸®¼öºÐÁ¦°ÅÀ²
  • free
    ÀÚÀ¯-, À¯¸®-
  • oxygen consumption
    »ê¼Ò¼Ò¸ð
  • oxygen content
    »ê¼ÒÇÔÀ¯·®
  • fraction in inspired oxygen
    ÈíÀÔ»ê¼Ò³óµµ
  • oxygen fraction in inspired air
    ÈíÀÔ»ê¼Ò³óµµ
  • oxygen
    »ê¼Ò
  • active oxygen
    Ȱµ¿»ê¼Ò, Ȱ¼º»ê¼Ò
  • hyperbaric oxygen
    °í¾Ð»ê¼Ò
  • saturation dissolved oxygen
    Æ÷È­¿ëÇØ»ê¼Ò·®
  • oxygen requirement
    »ê¼Ò¿ä±¸·®
  • arterial oxygen saturation
    µ¿¸ÆÇ÷»ê¼ÒÆ÷È­µµ
  • oxygen saturation
    »ê¼ÒÆ÷È­µµ
  • arterial oxygen tension
    µ¿¸ÆÇ÷»ê¼ÒºÐ¾Ð
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • bone marrow-derived cell
    °ñ¼öÀ¯·¡¼¼Æ÷
  • thymus-derived cell
    °¡½¿»ùÀ¯·¡¼¼Æ÷
  • derived protein
    À¯µµ´Ü¹éÁú
  • endothelium-derived contracting factor
    ³»ÇǼ¼Æ÷¼öÃàÀÎÀÚ
  • endothelium-derived relaxing factor
    ³»ÇǼ¼Æ÷ÀÌ¿ÏÀÎÀÚ
  • macrophage-derived growth factor
    Å«Æ÷½Ä¼¼Æ÷À¯·¡¼ºÀåÀÎÀÚ
  • platelet-derived growth factor
    Ç÷¼ÒÆÇÀ¯·¡¼ºÀåÀÎÀÚ, Ç÷¼ÒÆÇ±â¿ø¼ºÀåÀÎÀÚ
  • thymus-derived lymphocyte
    °¡½¿»ùÀ¯·¡¸²ÇÁ±¸
  • membrane-derived oligosaccharide
    ¼¼Æ÷¸·À¯·¡¼Ò´ç·ù
  • active oxygen
    Ȱµ¿»ê¼Ò, Ȱ¼º»ê¼Ò
  • alveolar oxygen pressure
    ÆóÆ÷»ê¼Ò¾Ð
  • alveolar-arterial oxygen gradient
    ÆóÆ÷µ¿¸Æ°£»ê¼ÒºÐ¾ÐÂ÷
  • arterial oxygen saturation
    µ¿¸ÆÇ÷»ê¼ÒÆ÷È­µµ
  • arterial oxygen tension
    µ¿¸ÆÇ÷»ê¼ÒºÐ¾Ð
  • oxygen aeration
    »ê¼ÒÅë±â
¿¾ ´ëÇÑÀÇÇù 2 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Free radicals
    ÀÚÀ¯(í»ë¦)¶óµðÄ®
  • hydroxyl radicals
    È÷µå·Ï½Ç ·¡µðÄ®, Hydroxyl radicals
  • Caesarian derived =caesarian-originated
    Á¦(¿Õ)Àý(°³)À¯·¡(ð¨èÝôîËÒ ë¦ÕÎ)ÀÇ.
  • EDCF (endothlium-derived contracting factor)
    ³»ÇǼ¼Æ÷¼º(Ò®ù«á¬øààõ) ¼öÃàÀÎÀÚ(â¥õêì×í­)
  • EDRF (endothlium-derived relaxing factor)
    ³»ÇǼ¼Æ÷¼º(Ò®ù«á¬øààõ) ÀÌ¿ÏÀÎÀÚ(ì¬èÐì×í­)
  • EDRF=£¾endothelium derived relaxing factor
    ³»ÇǼ¼Æ÷¼ºÀÌ¿ÏÀÎÀÚ.
  • T cell ; T lymphocyte ; thymus derived lymphocyte
    T¼¼Æ÷ ; T¸²ÇÁ? ; Èä¼±À¯·¡¸²ÇÁ?
  • platelet-derived growth factor
    Ç÷¼ÒÆÇÀ¯·¡ Áõ½ÄÀÎÀÚ
  • platelet-derived growth factor(PDGF)
    Ç÷¼ÒÆÇ À¯·¡ ¼ºÀå ÀÎÀÚ
  • platelet-derived growth factor(pdgf)
    ÆÇ-À¯µµ¼ºÀåÀÎÀÚ(úìá³÷ù-ë¯Óôà÷íþì×í­)
  • BOD=ÊÝbiochemical oxygen demand
    »ý¹°È­ÇÐÀû »ê¼Ò¿ä±¸·®.
  • Helium-oxygen mixture
    Çï·ý»ê¼ÒÈ¥ÇÕü
  • Hemoglobin-oxygen equilibrium curve
    Çì¸ð±Û·Îºó-»ê¼Ò°î¼±
  • OER [=oxygen enhancement ratio]
    »ê¼Ò°­È­À²
  • PAO2 => alveolar oxygen pressure
    ÆóÆ÷(øËøà)»ê¼Ò¾Ð
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • oxygen free radicals
    »ê¼ÒÀÚÀ¯¶óµðÄ®, »ê¼ÒÀ¯¸®±â, »ê¼ÒÀÚÀ¯±â
  • free radical formation,oxygen derived
    ÀÚÀ¯ ·¡µðÄ® Çü¼º, »ê¼Ò ±â¿ø¼º(ß«áÈ ÑÃê¹àõ)
  • hydroxyl radicals
    È÷µå·Ï½Ç ·¡µðÄ®, Hydroxyl radicals
  • free radical formation,oxygen toxicity
    ÀÚÀ¯ ·¡µðÄ® Çü¼º, »ê¼Òµ¶¼º(ß«áÈÔ¸àõ)
  • oxygen free radical
    »ê¼Ò ÀÚÀ¯±â
  • oxygen free-radical
    »ê¼Ò¶óµðÄ®, ¹ÝÀÀ¼º»ê¼Ò
  • bone marrow-derived cell
    °ñ¼öÀ¯·¡¼¼Æ÷
  • cell, thymus-derived
    °¡½¿»ùÀ¯·¡¼¼Æ÷, Èä¼±À¯·¡¼¼Æ÷
  • derived protein
    À¯µµ´Ü¹éÁú(¡­Ó±ÛÜòõ).
  • endothelium-derived contracting factor (EDCF)
    ³»ÇǼ¼Æ÷¼º¼öÃàÀÎÀÚ(Ò®ù«á¬øààõâ¥õêì×í­)
  • endothelium-derived relaxing factor
    ³»ÇǼ¼Æ÷¼º ÀÌ¿ÏÀÎÀÚ.
  • endothelium-derived relaxing factor
    ³»ÇǼ¼Æ÷¼º ÀÌ¿ÏÀÎÀÚ(¡­ì¬èÐì×í­).
  • endothelium-derived relaxing factor
    ³»ÇÇ ¼¼Æ÷¼º ÀÌ¿ÏÀÎÀÚ
  • endothelium-derived relaxing factor (EDRF)
    ³»ÇǼ¼Æ÷¼ºÀÌ¿ÏÀÎÀÚ
  • eosinophil-derived neurotoxin
    È£»ê±¸À¯·¡½Å°æµ¶¼Ò
´ëÇÑÇØºÎÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 8 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Articulations of free lower limb
    ÀÚÀ¯´Ù¸®°üÀý
    [¿¾ ¿ë¾î] ÀÚÀ¯ÇÏÁö°üÀý
  • Free margin
    ÀÚÀ¯¸ð¼­¸®
    [¿¾ ¿ë¾î] ÀÚÀ¯¿¬
  • Free part
    ÀÚÀ¯ºÎºÐ
    [¿¾ ¿ë¾î] À¯¸®ºÎ
  • Free nerve terminal
    ÀÚÀ¯½Å°æÁ¾¸»
    [¿¾ ¿ë¾î] ÀÚÀ¯½Å°æÁ¾¸»
  • Bones of free lower limb
    ÀÚÀ¯´Ù¸®»À
    [¿¾ ¿ë¾î] ÀÚÀ¯ÇÏÁö°ñ
  • Free villus
    ÀÚÀ¯À¶¸ð
    [¿¾ ¿ë¾î] À¯¸®À¶¸ð
  • Bones of free upper limb
    ÀÚÀ¯ÆÈ»À
    [¿¾ ¿ë¾î] ÀÚÀ¯»óÁö°ñ
  • Free border
    ÀÚÀ¯¸ð¼­¸®
    [¿¾ ¿ë¾î] ÀÚÀ¯¿¬
´ëÇѱâ»ýÃæÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • free-living ameba
    ÀÚÀ¯»ýȰ¾Æ¸Þ¹Ù
  • free-living cycle
    ÀÚÀ¯»ýȰȯ
  • free-living form
    ÀÚÀ¯»ýȰÇü
  • free-living generation
    ÀÚÀ¯»ýȰ¼¼´ë
  • free living species
    ÀÚÀ¯»ýȰÁ¾
´ëÇÑ»ýÈ­ÇкÐÀÚ»ý¹°ÇÐȸ ¿ë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • derived carbohydrate
    À¯µµ´çÁú(ë¯ÓôÓØòõ)
  • derived lipid
    À¯µµÁöÁú(ë¯Óôò·òõ)
  • derived protein
    À¯µµ´Ü¹éÁú(ë¯ÓôÓ±ÛÜòõ)
  • lymphocyte-derived chemotactic factor
    ¸²ÇÁ±¸-À¯µµ(ë¯Óô) È­ÇÐÁÖ¼ºÀÎÀÚ(ûùùÊñËà÷ì×í­)
  • platelet-derived growth factor
    Ç÷¼ÒÆÇÀ¯·¡(úìá³÷ùë¦ÕÎ) ¼ºÀåÀÎÀÚ(à÷íþì×í­)
  • primary derived protein
    ÀÏÂ÷ À¯µµ ´Ü¹éÁú(ìéó­ë¯ÓôÓ±ÛÜòõ)
  • secondary derived protein
    ÀÌÂ÷ À¯µµ´Ü¹éÁú(ì£ó­ë¯ÓôÓ±ÛÜòõ)
  • biochemical oxygen demand
    »ýÈ­ÇÐÀû(ßæûùùÊîÜ) »ê¼Ò¿ä±¸·®(ß«áÈé©Ï´Õá)
  • biological oxygen demand
    »ý¹°ÇÐÀû »ê¼Ò¿ä±¸·®(ßæÚªùÊîÜß«áÈé©Ï´Õá)
  • carbon-oxygen cycle
    ź¼Ò»ê¼Ò ȸ·Î(÷©áÈß«áÈüÞÖØ)
  • cytochrome c : oxygen oxidoreductase
    »çÀÌÅäÅ©·Ò c »ê¼Ò(ß«áÈ) ¿Á½Ãµµ¸®´öÅ×À̽º (ÔÒ) complex IV
  • oxygen
    »ê¼Ò(ß«áÈ)
  • oxygen carrier
    »ê¼Ò ¿î¹Ýü(ß«áÈê¡Úæô÷)
  • oxygen combining power
    »ê¼Ò°áÇÕ´É(úìäûß«áÈÌ¿ùêÒö)
  • oxygen cycle
    »ê¼Òȸ·Î(ß«áÈüÞÖØ)
KI ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • oxygen free radical
    »ê¼ÒÀÚÀ¯±â
  • T cell ¡ìthymus derived lymphocyte¡í
    T¼¼Æ÷ ¡ì Èä¼±À¯·¡ ¸²ÇÁ±¸¡í
  • oxygen
    »ê¼Ò
  • echo free
    ¿¡ÄÚ°¡ ¾ø´Â, ¹«¿¡ÄÚÀÇ
  • FID [=free induction decay]
    ÀÚÀ¯À¯µµºØ±«
  • free
    À¯¸®, ÀÚÀ¯ÀÇ, ¹«·áÀÇ
  • free edge
    ÀÚÀ¯º¯¿¬ºÎ
  • free electron
    ÀÚÀ¯ ÀüÀÚ
  • free induction decay [=FID]
    ÀÚÀ¯À¯µµºØ±«
  • free induction decay signal
    ÀÚÀ¯À¯µµºØ±«½ÅÈ£
  • free pleural fluid
    ÀÚÀ¯´Á¸·»ïÃâ¾×
  • free space
    ÀÚÀ¯°ø°£, ºó°ø°£
  • free surface
    ÀÚÀ¯¸é
  • free water in stationary tissue
    Á¤ÀûÁ¶Á÷³» ÀÚÀ¯¼öºÐ
  • free water proton
    ÀÚÀ¯¼öºÐ¾ç¼ºÀÚ
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
SF Sabin-Feldman [test]; safety factor; salt-free; scarlet fever; screen film; seminal fluid; serosal f...
AF abnormal frequency; acid-fast; adult female; afebrile; aflatoxin; albumin-free; albumose-free; aldeh...
CF calcaneal fibular [ligament]; calcium leucovorin; calf blood flow; calibration factor; cancer-free; ...
FF degree of fineness of abrasive particles; fat-free; father factor; fecal frequency; fertility factor...
FT Fallot tetralogy; false transmitter; family therapy; fast twitch; fatigue trial; fibrous tissue; fin...
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
ODFR Oxygen derived free radicals
OFR Oxygen derived free radicals
FOR Free Oxygen Radicals
OR Oxygen radicals
OFR Oxygen free radical
°æºÏ´ë Ä¡°ú´ëÇÐ ±¸°­³»°ú ±³½Ç »çÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
  • hydroxyl radicals
    È÷µå·Ï½Ç ·¡µðÄ®
  • bone marrow-derived lymphocyte
    °ñ¼ö À¯·¡ Àӯı¸
  • bursa-derived lymphocyte
    ÆÄºÎ¸®½Ã¿ì½º ³¶ À¯·¡ Àӯı¸
  • endothelium-derived relaxing factor
    ³»ÇÇ ¼¼Æ÷¼º ÀÌ¿Ï ÀÎÀÚ
  • eosinophil-derived neurotoxin
    È£»ê±¸ À¯·¡ ½Å°æ µ¶¼Ò
  • prodynorphin-derived fragment
    ÇÁ·Î´ÙÀ̳븣ÇÉ À¯·¡ ºÐÀý
  • proenkephalin-derived peptide
    ÇÁ·Î¿£ÄÉÆÈ¸° À¯·¡ ÆéƼµå
  • psychomerically derived test
    ½É¸® ÃøÁ¤ °Ë»ç
  • thymus-derived lymphocyte
    Èä¼± À¯·¡ Àӯı¸
  • alveolar arterial oxygen gradient
    ÆóÆ÷µ¿¸Æ°£ »ê¼Ò ºÐ¾ÐÂ÷
  • alveolar-arterial oxygen difference
    ÆóÆ÷-µ¿¸Æ »ê¼Ò Â÷ÀÌ
  • biochemical oxygen demand
    »ý¹°È­ÇÐÀû »ê¼Ò ¿ä±¸, »ý¹°È­ÇÐÀû »ê¼Ò ¿ä±¸·®
  • bridging oxygen atom
    °¡±³ »ê¼Ò
    2°³ÀÇ ±Û¶ó½º Çü¼º ¿øÀÚ¸¦ ¿¬°áÇÏ´Â »ê¼Ò.
  • chemical oxygen demand
    È­ÇÐÀû »ê¼Ò ¿ä±¸·®
  • hyperbaric oxygen chamber
    °í¾Ð »ê¼Ò½Ç
    °í¾ÐÀÇ »ê¼Ò¸¦ ÀÌ¿ëÇØ Àú»ê¼ÒÁõÀ» Ä¡·áÇϱâ À§ÇÑ ÀåÄ¡.
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
oxygen derived free radicals An atom or atom group having an unpaired electron on an oxygen atom, typically derived from molecular oxygen. For example, one-electron reduction of O2 produces the superoxide radical, O2-; other examples include the hydroperoxyl radical (HOO-), the hydroxyl radical (HO-), and nitric oxide (NO-).
(05 Mar 2000)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
free radicals Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
(12 Dec 1998)
brain-derived growth factor <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3.
In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF.
In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons.
Acronym: BDGF
(12 Dec 1998)
brain-derived neurotrophic factor <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3.
In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF.
In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons.
Acronym: BDGF
(12 Dec 1998)
mammary derived growth inhibitor Fatty acid binding protein that inhibits proliferation of mammary carcinoma cells.
(18 Nov 1997)
receptors, platelet-derived growth factor Specific molecular sites or structures on cell membranes that react with platelet-derived growth factor, its analogs, or antagonists, to elicit or to inhibit the specific response of the cell to this factor. Pdgf binds with different affinities and specificities to two structurally related receptors, the alpha-receptor and the beta-receptor. Both of these receptors are transmembrane proteins with an intracellular, ligand-stimulatable protein kinase domain.
(12 Dec 1998)
refuse-derived fuel (RDF) Fuel prepared from municipal solid waste. Noncombustible materials such as rocks, glass, and metals are removed, and the remaining combustible portion of the solid waste is choped or shreaded. RDF facilities process between 100 and 3000 tons of MSW per day.
(05 Dec 1998)
monocyte derived neutrophil chemotactic factor <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes.
It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4.
Acronym: IL-8
(12 Dec 1998)
platelet-derived growth factor <growth factor> The major mitogen in serum for growth in culture of cells of connective tissue origin. It consists of 2 different but homologous polypeptides A and B (~30,000 D) linked by disulphide bonds. Believed to play a role in wound healing.
It is carried in the alpha-granules of platelets and is released when platelets adhere to traumatised tissues. Connective tissue cells near the traumatised region respond by initiating the process of replication.
The B chain is almost identical in sequence to p28sis, the transforming protein of simian sarcoma virus, that can transform only those cells that express receptors for platelet derived growth factor, suggesting that transformation is caused by autocrine stimulation. The receptor is a tyrosine kinase.
Acronym: PDGF
(12 Dec 1998)
schwannoma derived growth factor <growth factor> A growth factor containing an EGF like domain, mitogenic for astrocytes, Schwann cells and fibroblasts.
(18 Nov 1997)
derived protein A derivative of protein effected by chemical change, e.g., hydrolysis.
(05 Mar 2000)
thymus derived lymphocyte <haematology, immunology> A class of lymphocytes, so called because they are derived from the thymus and have been through thymic processing. Involved primarily in controlling cell-mediated immune reactions and in the control of B-cell development. The T-cells coordinate the immune system by secreting lymphokine hormones.
There are 3 fundamentally different types of t cells : helper, killer, and suppressor. Each has many subdivisions. T-cells are also called t lymphocytes.
They bear T-cell antigen receptors (CD3) and lack Fc or C3b receptors. Major T-cell subsets are CD4 (mainly helper cells) and CD8 (mostly cytotoxic or suppressor T-cells). Uncontrolled proliferation of this type of cell gives rise to T-cell leukaemia/lymphoma.
(21 Jun 1999)
endothelium-derived growth factor synthase <enzyme> Converts l-arginine to a smooth muscle relaxing factor and stimulates the formation of cyclic-GMP
Registry number: EC 1.5.1.-
Synonym: edrf synthase
(26 Jun 1999)
endothelium derived relaxation factor <biochemistry> This compound is produced from L arginine by the enzyme nitric oxide synthase. Acts as a potent vasorelaxant via elevation of intracellular cGMP in vascular smooth muscle.
Synthesis of nitric oxide is not confined to endothelium, isoforms of nitric oxide synthase are also found in brain, neutrophils and platelets.
Synonym: endothelium derived relaxation factor.
Acronym: NO
(29 Dec 1997)
endothelium-derived relaxing factor A labile humoral agent released by the vascular endothelium that mediates the relaxation induced by some vasodilators such as acetylcholine and bradykinin. Edrf also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. These actions are believed to be mediated through stimulation of guanylate cyclase and the consequent elevation of cyclic guanosine 3',5'-monophosphate. Edrf is thought to be nitric oxide or a ready source of it. The factor is believed to be unstable and acts only locally in vivo.
(12 Dec 1998)
alactic oxygen debt That part of the oxygen debt that is not lactacid oxygen debt; during recovery, stores of ATP and creatine phosphate must be replenished by oxidative metabolism, and a small amount of oxygen is also needed to restore the normal oxyhemoglobin levels throughout the circulating blood.
(05 Mar 2000)
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