| OA | obstructive apnea; occipital artery; occipito-anterior; occiput anterior; octanoic acid; ocular albi... |
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| 5'-FOA | 5'-fluoro-orotic acid |
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| OA | Orotic acid |
| orotic acid | Intermediate in the de novo synthesis of pyrimidines. Linked glycosidically to ribose 5' phosphate, orotate forms the pyrimidine nucleotide orotidylate, that on decarboxylation at position 5 of the pyrimidine ring yields the major nucleotide uridylate (uridine 5' phosphate). (18 Nov 1997) |
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| orotic aciduria | A rare disorder of pyrimidine metabolism characterised by hypochromic anaemia with megaloblastic changes in bone marrow, leukopenia, retarded growth, and urinary excretion of orotic acid; autosomal recessive inheritance. Origin: orotic acid + G. Ouron, urine (05 Mar 2000) |
Synonyms : Potassium Orotate, Sodium Orotate, Zinc Orotate, Acid, Orotic, Orotate, Potassium, Orotate, Sodium, Orotate, Zinc
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| orotic acid |
Intermediate in the de novo synthesis of pyrimidines. Linked glycosidically to ribose 5' phosphate, orotate forms the pyrimidine nucleotide orotidylate, that on decarboxylation at position 5 of the pyrimidine ring yields the major nucleotide uridylate (uridine 5' phosphate).
Ãâó: www.lactospore.com/glossary.htm
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| oroticaciduria |
1. excessive orotic acid in the urine, occurring in several metabolic disorders and also resulting from administration of certain drugs. 2. an autosomal recessive defect of pyrimidine metabolism due to deficiency of orotate phosphoribosyltransferase (OPRT) or orotidine-5′-phosphate decarboxylase (ODC). Manifestations include crystalluria and excessive excretion of orotic acid in the urine, megaloblastic anemia with hypochromic, microcytic circulating erythrocytes, and physical and mental growth retardation. There are two biochemical types: type I is due to deficiency of both OPRT and ODC activities; type II is due to deficiency of ODC activity only.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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