| OPRT | orotate phosphoribosyltransferase |
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| OPRTase | orotate phosphoribosyltransferase |
| HPRT | hypoxanthine-guanine phosphoribosyltransferase |
| OPRT | Orotate phosphoribosyl transferase |
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| APRT | Adenine phosphoribosyltransferase |
| HPRT | Hypoxanthine guanine phosphoribosyltransferase |
| hprt | Hypoxanthine phosphoribosyltransferase gene |
| PRTase | Phosphoribosyltransferase |
| orotate phosphoribosyltransferase | <enzyme> The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. Chemical name: Orotidine-5'-phosphate:pyrophosphate phospho-alpha-D-ribosyltransferase Registry number: EC 2.4.2.10 (12 Dec 1998) |
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| dihydro-orotate | <biochemistry> An intermediate in the biosynthesis of pyrimidines. Chemical name: L-5,6-dihydroorotate (21 Jun 2000) |
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| orotate | A salt or ester of orotic acid. (05 Mar 2000) |
| adenine phosphoribosyltransferase | <enzyme> An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into nucleic acids. Chemical name: AMP:pyrophosphate phospho-D-ribosyltransferase Registry number: EC 2.4.2.7 (12 Dec 1998) |
| aminoglycoside phosphoribosyltransferase | <enzyme> Coded by neo-gene; involved in kanamycin resistance; no other information given on reaction 8/93 Registry number: EC 2.4.2.- Synonym: aminoglycosidephosphoribosyltransferase (26 Jun 1999) |
| anthranilate phosphoribosyltransferase | <enzyme> An enzyme that catalyses the formation of n-5'-phosphoribosylanthranilic acid from anthranilate and phosphoribosylpyrophosphate, the first step in tryptophan synthesis in e. Coli. It exists in a complex with anthranilate synthase in bacteria. Chemical name: N-(5-Phospho-D-ribosyl)-anthranilate:pyrophosphate phospho-alpha-D-ribosyltransferase Registry number: EC 2.4.2.18 (12 Dec 1998) |
| ATP phosphoribosyltransferase | <enzyme> An enzyme that catalyses the first step of the pathway for histidine biosynthesis in salmonella typhimurium. ATP reacts reversibly with 5-phosphoribosyl-1-pyrophosphate to yield n-1-(5'-phosphoribosyl)-ATP and pyrophosphate. Chemical name: 1-(5-Phospho-D-ribosyl)-ATP:pyrophosphate phospho-alpha-D- ribosyltransferase Registry number: EC 2.4.2.17 (12 Dec 1998) |
| phosphoribosyltransferase | One of a group of enzymes (EC sub-subclass 2.4.2, pentosyltransferases) that transfers d-ribose 5-phosphate from 5-phospho-alpha-d-ribosyl pyrophosphate to a purine, pyrimidine, or pyridine acceptor, forming a 5'-nucleotide and inorganic pyrophosphate, or d-ribose from d-ribosyl phosphate to a base, forming a nucleoside, or similar pentose transfers; important in nucleotide biosynthesis. Specific phosphoribosyltransferases are preceded by the name of the acceptor base, e.g., uracil phosphoribosyltransferase (i.e., uracil + PRPP &dblarr; UMP + pyrophosphate). (05 Mar 2000) |
| purine phosphoribosyltransferase | <enzyme> Specific purine phosphoribosyltransferases are EC 2.4.2.7 and 2.4.2.8. Registry number: EC 2.4.2.- (26 Jun 1999) |
| pyrimidine phosphoribosyltransferase | <enzyme> Pyrimidine monophosphate and pyrophosphate gives pyrimidine and phosphoribosyl pyrophosphate; acts with uracil, orotic acid or fluorouracil Registry number: EC 2.4.2.- (26 Jun 1999) |
| hypoxanthine guanine phosphoribosyltransferase | <enzyme> An enzyme that catalyses the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the lesch-nyhan syndrome, while partial deficiency results in overproduction of uric acid. Chemical name: IMP:pyrophosphate phospho-D-ribosyltransferase Registry number: EC 2.4.2.8 (12 Dec 1998) |
| hypoxanthine guanine phosphoribosyltransferase deficiency | A sex-linked inherited metabolic disorder; complete deficiency results in Lesch-Nyhan syndrome; incomplete deficiency is associated with acute gouty arthritis and renal stones. (05 Mar 2000) |
| hypoxanthine-guanine-xanthine phosphoribosyltransferase | <enzyme> From tritrichomonas foetus; in contrast to EC 2.4.2.8, this enzyme also uses xanthine as substrate; mw 24 kD Registry number: EC 2.4.2.- Synonym: hgxprtase (26 Jun 1999) |
| hypoxanthine phosphoribosyltransferase | <enzyme> An enzyme that catalyses the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the lesch-nyhan syndrome, while partial deficiency results in overproduction of uric acid. Chemical name: IMP:pyrophosphate phospho-D-ribosyltransferase Registry number: EC 2.4.2.8 (12 Dec 1998) |
| nicotinamide phosphoribosyltransferase | <enzyme> Utilises nicotinamide, mg(2+), prpp and ATP Registry number: EC 2.4.2.12 Synonym: nmn pyrophosphorylase (26 Jun 1999) |
| nicotinatenucleotide-dimethylbenzimidazole phosphoribosyltransferase | <enzyme> Involved in the synthesis of adenosyl-cobalamin (coenzyme b12); amino acid sequence given in second source Registry number: EC 2.4.2.21 Synonym: nicotinate ribonucleotide benzimidazole phosphoribosyltransferase, trans-n-glycosidase, nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, cobu gene product, cobt protein, scobt protein, cobt gene product (26 Jun 1999) |
Synonyms : OMPase, Orotidine-5'-Monophosphate Phosphohydrolase, Orotidine 5' Monophosphate Phosphohydrolase, Orotidine 5' Phosphate Pyrophosphorylase, Phosphohydrolase, Orotidine-5'-Monophosphate, Phosphoribosyltransferase, Orotate, Phosphorylase, Orotidylic Acid
| orotate phosphoribosyltransferase |
[EC 2.4.2.10] an enzyme activity of the transferase class that catalyzes the transfer to orotate of a ribosyl group from phosphoribosylpyrophosphate (PRPP) to form orotidine 5′-phosphate as a step in the synthesis of pyrimidine nucleotides. The catalytic sites for this activity and for orotidine 5′-phosphate decarboxylase (ODC) activity occur on a single protein, called UMP synthase; deficiency of both activities, an autosomal recessive trait, causes hereditary oroticaciduria type I.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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