| OPRT | orotate phosphoribosyltransferase |
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| OPRTase | orotate phosphoribosyltransferase |
| OPRT | Orotate phosphoribosyl transferase |
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| orotate | A salt or ester of orotic acid. (05 Mar 2000) |
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| orotate phosphoribosyltransferase | <enzyme> The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. Chemical name: Orotidine-5'-phosphate:pyrophosphate phospho-alpha-D-ribosyltransferase Registry number: EC 2.4.2.10 (12 Dec 1998) |
| dihydro-orotate | <biochemistry> An intermediate in the biosynthesis of pyrimidines. Chemical name: L-5,6-dihydroorotate (21 Jun 2000) |
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Synonyms : OMPase, Orotidine-5'-Monophosphate Phosphohydrolase, Orotidine 5' Monophosphate Phosphohydrolase, Orotidine 5' Phosphate Pyrophosphorylase, Phosphohydrolase, Orotidine-5'-Monophosphate, Phosphoribosyltransferase, Orotate, Phosphorylase, Orotidylic Acid
| orotate |
a dissociated form of orotic acid.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| orotate phosphoribosyltransferase |
[EC 2.4.2.10] an enzyme activity of the transferase class that catalyzes the transfer to orotate of a ribosyl group from phosphoribosylpyrophosphate (PRPP) to form orotidine 5′-phosphate as a step in the synthesis of pyrimidine nucleotides. The catalytic sites for this activity and for orotidine 5′-phosphate decarboxylase (ODC) activity occur on a single protein, called UMP synthase; deficiency of both activities, an autosomal recessive trait, causes hereditary oroticaciduria type I.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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