| CDSC | Communicable Diseases Surveillance Centre [London] |
|---|---|
| ECETOC | European Centre for Ecotoxicity and Toxicology of Chemicals |
| ECVAM | European Centre for the Validation of Alternative Methods |
| GECC | Government Employees' Clinic Centre |
| MSDC | Mass Spectrometry Data Centre |
| MTOC | microtubule organising centre |
|---|---|
| BOOP | Bronchiolitis Obliterans Organising Pneumonia |
| SOM | Self Organising Map |
| CEPH | Centre D'Etude du Polymorphisme Humain |
| CDC | Centre for Disease Control |
| organising centre | <cell biology> See microtubule organising centre. (18 Nov 1997) |
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| microtubule organising centre | <cell biology> Rather amorphous region of cytoplasm from which microtubules radiate. The pattern and number of microtubules is determined by the microtubule organising centre. The pericentriolar region is the major microtubule organising centre in animal cells, the basal body of a cilium is another example. Activity of microtubule organising centres can be regulated, but the mechanism is unclear. Acronym: MTOC (18 Nov 1997) |
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| active centre | The part of a macromolecule at which a substrate or ligand, upon binding, produces biological activity; for an enzyme, this is the catalytic centre, the site on an enzyme that catalyses the reaction. (05 Mar 2000) |
| anospinal centre | The centre in the spinal cord that controls the contraction of the anal sphincter. (05 Mar 2000) |
| asymmetric centre | <chemistry> Same as a chiral centre, a tetrahedral carbon atom that bears four different substituents. (09 Jan 1998) |
| Broca's centre | The posterior part of the inferior frontal gyrus of the left or dominant hemisphere, corresponding approximately to Brodmann's area 44; Broca identified this region as an essential component of the motor mechanisms governing articulated speech. Synonym: Broca's area, Broca's field, motor speech centre. (05 Mar 2000) |
| Budge's centre | The preganglionic motor neurons in the first thoracic segment of the spinal cord which give rise to the sympathetic innervation of the dilator muscle of the eye's pupil. Synonym: Budge's centre. (05 Mar 2000) |
| vasomotor centre | Diffuse area of the reticular formation in the lateral medulla containing neurons that control vascular tone; consists of separate vasodepressor and vasopressor areas. (05 Mar 2000) |
| reaction centre | <plant biology> The site in the chloroplast that receives the energy trapped by chlorophyll and accessory pigments and initiates the electron transfer process. A photosynthetic complex containing chlorophyll (or bacteriochlorophyll) and other components, within which occurs the initial electron transfer reactions of photophosphorylation. (09 Oct 1997) |
| germinal centre | Areas within lymph nodes where B lymphocytes rapidly divide. (09 Oct 1997) |
| germinal centre kinase | <enzyme> A human ste20 homolog; mw 97 kD; has been sequenced Registry number: EC 2.7.10.- Synonym: germinal centre kinase gck, gc kinase, bl44 gene product (26 Jun 1999) |
| germinal centre of Flemming | The lightly staining centre in a lymphatic nodule in which the predominant cells are large lymphocytes and macrophages. Synonym: reaction centre. (05 Mar 2000) |
| catalytic centre | See: active centre. (05 Mar 2000) |
| cell centre | Microtubule organising centre of the cell, the pericentriolar region. (18 Nov 1997) |
| vital centre | Centre essential to life; usually refers to the centres located in the medulla oblongata which are necessary for the maintenance of respiration and circulation. (05 Mar 2000) |
| medullary centre | The great mass of white matter composing the interior of the cerebral hemisphere; the name refers to the general shape of this white core in horizontal sections of the hemisphere. Synonym: centrum medullare, centrum ovale, medullary centre, semioval centre, Vicq d'Azyr's centrum semiovale, Vieussens' centrum. (05 Mar 2000) |
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