| DST | 1) Donor Specific Transfusion 2) Dexamethasone Suppression Test |
|---|---|
| CAST | calpastatin; Cardiac Arrhythmia Suppression Trial; Children of Alcoholism Screening Test |
| DST | desensitization test; dexamethasone suppression test; dihydrostreptomycin; disproportionate septal t... |
| HTS | head traumatic syndrome; HeLa tumor suppression; human thyroid-stimulating hormone, human thyroid st... |
| PST | pancreatic suppression test; paroxysmal supraventricular tachycardia; penicillin, streptomycin, and ... |
| CAST | Cardiac Arrhythmia Suppression Trial |
|---|---|
| CISS | Chromosomal in situ suppression |
| CSD | Conditioned Suppression of Drinking |
| DSI | Depolarisation-induced suppression of inhibition |
| DST | Dexamethasone Suppression Test |
| opal | <chemical> A mineral consisting, like quartz, of silica, but inferior to quartz in hardness and specific gravity. The precious opal presents a peculiar play of colours of delicate tints, and is highly esteemed as a gem. One kind, with a varied play of colour in a reddish ground, is called the harlequin opal. The fire opal has colours like the red and yellow of flame. Common opal has a milky appearance. Menilite is a brown impure variety, occurring in concretions at Menilmontant, near Paris. Other varieties are cacholong, girasol, hyalite, and geyserite. Origin: L. Opalus: cf. Gr, Skr. Upala a rock, stone, precious stone: cf. F. Opale. Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| opal codon | <molecular biology> The codon UGA, one of the three that causes termination of protein synthesis. (18 Nov 1997) |
| opal mutation | <molecular biology> Mutation that changes any codon to the termination codon UGA. (18 Nov 1997) |
| opal suppressor | <molecular biology> A gene that codes for an altered tRNA so that its anticodon can recognise the opal codon and thus allows the continuation of protein synthesis. A suppressor of an opal mutation is a tRNA that is charged with the amino acid corresponding to the original codon or a neutral substitute. Some eukaryote cells normally synthesise opal suppressor tRNAs. The function of these is not clear and they usually do not prevent normal termination of protein synthesis at an opal codon. (18 Nov 1997) |
| ACTH suppression test | <investigation> A test that measures the response of the adrenal glands to ACTH. In this case, dexamethasone is given to the patient and then blood cortisol levels are measured. Under normal conditions, cortisol levels should drop in response to dexamethasone. In this test one milligram of dexamethasone is administered in the morning and then the blood is drawn for analysis the following morning. Abnormal test results can indicate Cushing's syndrome. (27 Sep 1997) |
| bone marrow suppression | <oncology, pharmacology> A side effect of many anticancer and antiviral drugs, including AZT. Bone marrow suppression leads to a decrease in white blood cells, red blood cells and platelets. Such reductions in turn result in anaemia, bacterial infections and spontaneous or excess bleeding. (09 Oct 1997) |
| growth hormone suppression test | <investigation> A test to determine if growth hormone is suppressed by hyperglycaemia. Growth hormone blood levels are determined sequentially after ingestion of a glucose-rich meal. If growth hormone levels remain elevated (after the glucose is given) then acromegaly or gigantism is suspected. (27 Sep 1997) |
| cortisol suppression test | <investigation> A test that measures the response of the adrenal glands to ACTH. In this case, dexamethasone is given to the patient and then blood cortisol levels are measured. Under normal conditions, cortisol levels should drop in response to dexamethasone. In this test one milligram of dexamethasone is administered in the morning and then the blood is drawn for analysis the following morning. Abnormal test results can indicate Cushing's syndrome. (27 Sep 1997) |
| nonsense suppression | Mutant tRNAs that read a chain termination codon as the signal for incorporation of a specific amino acid residue. (05 Mar 2000) |
| suppression | 1. The act of suppressing, or the state of being suppressed; repression; as, the suppression of a riot, insurrection, or tumult; the suppression of truth, of reports, of evidence, and the like. 2. <medicine> Complete stoppage of a natural secretion or excretion; as, suppression of urine; used in contradiction to retention, which signifies that the secretion or excretion is retained without expulsion. 3. Omission; as, the suppression of a word. Synonym: Overthrow, destruction, concealment, repression, detention, retention, obstruction. Origin: L. Suppressio: cf. F. Suppression. Source: Websters Dictionary (01 Mar 1998) |
| suppression amblyopia | The suppression of the central vision in one eye when the images from the two eyes are so different that they cannot be fused into one. This may be due to: 1) faulty image formation (sensory amblyopia); 2) a large difference in refraction between the two eyes (anisometropic amblyopia); or 3) the two eyes pointing in different directions (strabismic amblyopia). Most suppression amblyopia can be reversed if appropriately treated before age 6 years. Synonym: amblyopia ex anopsia. (05 Mar 2000) |
| suppression, genetic | The restoration of the wild-type phenotype in an organism possessing a mutationally altered genotype. The effects of the mutation may be suppressed by a second "suppressor" mutation on a different gene, by a suppressor mutation on the same gene but located at a distance from the site of the primary mutation, or by the presence of a cytoplasmic suppressor due to a change in non-chromosomal DNA. (12 Dec 1998) |
| dexamethasone suppression test | <endocrinology, investigation> A test that measures the response of the adrenal glands to ACTH. Dexamethasone is given to the patient and then blood cortisol levels are measured. Under normal conditions, cortisol levels should drop in response to dexamethasone. In this test one milligram of dexamethasone is administered in the morning and then the blood is drawn for analysis the following morning. Abnormal test results can indicate Cushing's syndrome. (27 Sep 1997) |
| immune suppression | Suppression of the immune response by some compound or agent. (05 Mar 2000) |
| intergenic suppression | The situation where a primary gene and the gene that suppresses it do not lie in the same chromosomal locus. Compare: intragenic suppression. (18 Nov 1997) |
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