| ¿µ¹® | codon | ÇÑ±Û | ÄÚµ·, À¯ÀüÀÚºÎÈ£ |
|---|---|---|---|
| ¼³¸í | ´Ü¹éÁúÀÇ ¾Æ¹Ì³ë»ê ¹è¿À» ±ÔÁ¤ÇÏ´Â Àü·É RNAÀÇ 3¿°±â ¹è¿À» ¸»ÇÑ´Ù. ¾Æ¹Ì³ë»êÀÇ À¯Àü¾ÏÈ£¶ó°íµµ ÇÑ´Ù. Àü »ý¹°À» ÅëÇØ¼ °øÅëÀ¸·Î DNAÀÇ ¿°±â¹è¿·Î Ç¥½ÃÇÒ ¼öµµ ÀÖ´Ù. RNA¶Ç´Â DNA¸¦ ±¸¼ºÇÏ´Â ³× Á¾·ùÀÇ ¿°±â(´ºÅ¬·¹¿ÀƼµå)¿¡¼ ¸¸µé¾îÁö´Â ¿°±â¹è¿ÀÇ ÃѼö´Â 64°³·Î, ±× ÁßÀÇ 61°³°¡ ¾Æ¹Ì³ë»êÀ» ÄÚµåÇϰí ÀÖ´Ù. ³ª¸ÓÁö ¼¼ °³(UAA, UAG, UGA)´Â ´Ü¹éÁú ÇÕ¼ºÀ» Á¤Áö½Ãų ºÎÈ£·Î Á¤ÁöÄÚµ·À̶ó ºÒ¸°´Ù. ´Ü¹éÁúÇÕ¼ºÀÇ °³½ÃÄÚµ·(AUG)Àº ¸ÞƼ¿À´ÑÀÇ ÄÚµ·°ú °øÅëÀÌÁö¸¸ °³½Ã tRNA¿¡ ÀÇÇØ¼ ÀνĵȴÙ. |
||
| CAI | Codon Adaptation Index |
|---|---|
| PTC | premature termination codon |
| ochre codon | The codon UAA, one of the three that causes termination of protein synthesis. The most frequent termination codon in E. Coli genes. (18 Nov 1997) |
|---|
| ochre | <chemical> A impure earthy ore of iron or a ferruginous clay, usually red (hematite) or yellow (limonite), used as a pigment in making paints, etc. The name is also applied to clays of other colours. A metallic oxide occurring in earthy form; as, tungstic ocher or tungstite. Origin: F.ocre, L. Ochra, fr. Gr, from pale, pale yellow. <chemical> See Ocher. Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| ochre mutation | Mutation that changes any codon to the termination codon UAA. (18 Nov 1997) |
| ochre suppressor | A gene that codes for an altered tRNA so that its anticodon can recognise the ochre codon and thus allows the continuation of protein synthesis. A suppressor of an ochre mutation is a tRNA that is charged with the amino acid corresponding to the original codon or a neutral substitute. Ochre suppressors will also suppress amber codons. (18 Nov 1997) |
| uran-ochre | <chemical> A yellow, earthy incrustation, consisting essentially of the oxide of uranium, but more or less impure. Origin: Cf. F. Uranochre. Source: Websters Dictionary (01 Mar 1998) |
| amber codon | <molecular biology> One of the three terminator codons. Its sequence is UAG. See: ochre codon, opal codon. (18 Nov 1997) |
| ambiguous codon | <molecular biology> A codon that codes for more than one amino acid. (09 Oct 1997) |
| codon | <molecular biology> The coding unit of DNA that specifies the function of the corresponding messenger RNA. A triplet of bases recognised by anticodons on transfer RNA and hence specifying an amino acid to be incorporated into a protein sequence. The code is degenerate, i.e. Each amino acid has more than one codon. The stop codon determines the end of a polypeptide. (18 Nov 1997) |
| codon, initiator | Any codon that directs initiation of genetic translation (translation, genetic) by stimulating the binding of initiator trna. In prokaryotes, the codons aug or gug can act as initiators while in eukaryotes, aug is the only initiator codon. (12 Dec 1998) |
| codon, nonsense | A codon that is not assigned to an amino acid or to any stop signal. It was originally thought that nonsense codons were synonymous with terminator codons (codon, terminator) in that they signaled termination of a protein chain. Recent studies have found this not to be true. (12 Dec 1998) |
| codon, terminator | Any codon that signals the termination of genetic translation (translation, genetic) by triggering the hydrolysis of the aminoacyl bond connecting the completed polypeptide to the trna. Terminator codons (uaa, uag, and uga) do not specify amino acids. (12 Dec 1998) |
| punctuation codon | <molecular biology> The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in E. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single GTP requiring factor, eRF. See: ochre suppressor, amber suppressor. (13 Jan 1998) |
| start codon | The codon 5' AUG in mRNA, at which polypeptide synthesis is started. It is recognised by formylmethionyl tRNA in bacteria and by methionyl tRNA in eukaryotes. (18 Nov 1997) |
| stop codon | <molecular biology> The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in E. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single GTP requiring factor, eRF. See: ochre suppressor, amber suppressor. (13 Jan 1998) |
| nonsense codon | <molecular biology> The three codons, UAA (known as ochre), UAG (amber) and UGA (opal), that do not code for an amino acid but act as signals for the termination of protein synthesis. Any mutation that causes a base change which produces a nonsense codon results in premature termination of protein synthesis and probably a nonfunctional or nonsense protein. (13 Nov 1997) |
| initiating codon | The trinucleotide AUG (or sometimes GUG) that codes for the first amino acid in protein sequences, formylmethionine; the latter is often removed post-transcriptionally. Synonym: start codon. (05 Mar 2000) |
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