| OAA/S | Observer Assessment of Alertness/Sedation |
|---|---|
| B | bias |
| observer | One who perceives, notices, or watches; in behavioural research with humans, the investigator or his/her surrogate. Origin: L. Observo, to watch Nonparticipant observer, an investigator who studies a group of subjects engaged in certain activities but does not directly participate in these activities, presumably being able to study them more objectively. Participant observer, an investigator who while studying the activities of a group of subjects also participates in their activities, presumably being able to gain more detailed, relevant information but with less objectivity. (05 Mar 2000) |
|---|---|
| observer variation | The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material). (12 Dec 1998) |
| bias | <statistics> In a clinical trial, bias refers to effects that a conclusion that may be incorrect as, for example, when a researcher or patient knows what treatment is being given. To avoid bias, a blinded study may be done. Any deviation of results or inferences from the truth, or processes leading to such deviation. Bias can result from several sources: one-sided or systematic variations in measurement from the true value (systematic error); flaws in study design; deviation of inferences, interpretations, or analyses based on flawed data or data collection; etc. There is no sense of prejudice or subjectivity implied in the assessment of bias under these conditions. (27 Jun 1999) |
| publication bias | The influence of study results on the chances of publication and the tendency of investigators, reviewers, and editors to submit or accept manuscripts for publication based on the direction or strength of the study findings. Publication bias has an impact on the interpretation of clinical trials and meta-analyses. Bias can be minimised by insistence by editors on high-quality research, thorough literature reviews, acknowledgement of conflicts of interest, modification of peer review practices, etc. (12 Dec 1998) |
| selection bias | The introduction of error due to systematic differences in the characteristics between those selected and those not selected for a given study. In sampling bias, error is the result of failure to ensure that all members of the reference population have a known chance of selection in the sample. (12 Dec 1998) |
| insurance selection bias | Adverse of favourable selection bias exhibited by insurers or enrollees resulting in disproportionate enrollment of certain groups of people. (12 Dec 1998) |
| internal bias | Applied to the motile behaviour of crawling cells that, in the short term, show persistence and do not behave as true random walkers. Any intrinsic regulation of the random motile behaviour of the cell could be considered as internal bias. (18 Nov 1997) |
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