| ASO | administrative services only; allele-specific oligonucleoside; antistreptolysin O; arteriosclerosis ... |
|---|---|
| cALL | common null cell acute lymphocytic leukemia |
| H0 | null hypothesis |
| ASA | Allele Specific Amplification |
|---|---|
| ADO | Allele drop-out |
| ASO | Allele specific oligonucleotide |
| AS-PCR | Allele specific polymerase chain reaction |
| MASA | Mutant allele specific amplification |
| allele | <genetics> Any one of a series of two or more different genes that occupy the same position (locus) on a chromosome. Since autosomal chromosomes are paired, each autosomal locus is represented twice. If both chromosomes have the same allele, occupying the same locus, the condition is referred to as homozygous for this allele. If the alleles at the two loci are different, the individual or cell is referred to as heterozygous for both alleles. (15 Nov 1997) |
|---|---|
| amorphic allele | <genetics, molecular biology> An allele which is genetically inactive. (05 Feb 1998) |
| codominant allele | In genetics, denoting an equal degree of dominance of two genes, both being expressed in the phenotype of the individual; e.g., genes A and B of the ABO blood group are codominant; individuals with both are type AB. (05 Mar 2000) |
| silent allele | 1. <genetics> A gene which is inactive. Thus, an amorphic gene. 2. <cell biology> Something that lacks a discernible shape and thus can be describes as amorphous. (05 Feb 1998) |
| Rh null syndrome | <syndrome> A lack of all Rh antigens, compensated haemolytic anaemia, and stomatocytosis. (05 Mar 2000) |
| null | 1. Something that has no force or meaning. 2. That which has no value; a cipher; zero. <physics> Null method, a zero method. See Zero. Source: Websters Dictionary (01 Mar 1998) |
| null cell | Lymphocytes lacking typical markers of T or B-cells capable of lysing a variety of tumour or virus infected cells without obvious antigenic stimulation, also effect antibody dependent cell cytotoxicity, carry in humans CD16 marker. (18 Nov 1997) |
| null-cell adenoma | <tumour> An adenoma of the hypophysis composed of cells for which there is no overt evidence or hormone production, but which usually produces hypopituitarism and visual disturbances by compression of adjacent structures; approximately one third of these tumours have cells with abundant mitochondria (oncocytes) that are somewhat larger than the monocytic null cells. Synonym: undifferentiated cell adenoma. (05 Mar 2000) |
| null cells | Large granular lymphocytes that lack surface markers/membrane associated proteins of either B or T lymphocytes. (05 Mar 2000) |
| null hypothesis | The assumption that any observed difference between two samples of a statistical population is purely accidental and not due to systematic causes. (05 Dec 1998) |
| null mutation | Change in a gene that leads to nothing, for example to no enzyme or to a nonfunctioning enzyme. (12 Dec 1998) |
| lymphocytes, null | A class of lymphocytes characterised by the lack of surface markers specific for either t or b lymphocytes. (12 Dec 1998) |
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