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  • nonsense mutation
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  • nonsense triplet
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  • mutation, nonsense
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  • nonsense mutation
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  • nonsense mutation
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  • nonsense suppressor
    ³Í¼¾½º ¾ï¾ÐÀÚ(åääâí­)
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NST Nonsense Syllable Test
NMD Nonsense-mediated mRNA decay
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codon, nonsense A codon that is not assigned to an amino acid or to any stop signal. It was originally thought that nonsense codons were synonymous with terminator codons (codon, terminator) in that they signaled termination of a protein chain. Recent studies have found this not to be true.
(12 Dec 1998)
nonsense As used in genetics, relating to a mutation that causes a sequence such that the growing peptide chain terminates, often after several incorrect amino acid residues are incorporated.
(05 Mar 2000)
nonsense codon <molecular biology> The three codons, UAA (known as ochre), UAG (amber) and UGA (opal), that do not code for an amino acid but act as signals for the termination of protein synthesis.
Any mutation that causes a base change which produces a nonsense codon results in premature termination of protein synthesis and probably a nonfunctional or nonsense protein.
(13 Nov 1997)
nonsense mutation <molecular biology> A mutation that causes a polypeptide chain to be ended prematurely.
(13 Nov 1997)
nonsense strand <molecular biology> DNA that does not code for part of a polypeptide chain or RNA.This includes introns and pseudo genes. In eukaryotes the majority of the DNA is noncoding. Noncoding strand refers to the so called nonsense strand, as opposed to the sense strand which is actually translated into mRNA.
(18 Nov 1997)
nonsense suppression Mutant tRNAs that read a chain termination codon as the signal for incorporation of a specific amino acid residue.
(05 Mar 2000)
nonsense syndrome <syndrome> A psychotic-like condition, without the symptoms and signs of a traditional psychosis, occurring typically in prisoners who feign insanity; e.g., such a person, when asked to multiply 6 by 4, will give 23 as the answer, or he will call a key a lock.
See: malingering, factitious disorder.
Synonym: nonsense syndrome, syndrome of approximate relevant answers, syndrome of deviously relevant answers.
(05 Mar 2000)
nonsense triplet A trinucleotide (codon) in which a base change to a termination codon results in premature termination of the growing polypeptide chain and, consequently, incomplete protein molecules, a termination codon.
(05 Mar 2000)
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nonsense m. a mutation in which one of the three terminator codons in the mRNA (UAG, amber; UAA, ochre; UGA, umber or opal), used to signal the end of a polypeptide, appears in the middle of a genetic message, causes premature termination of transcription, and releases incomplete, generally nonfunctional polypeptides from the ribosome. See also missense m.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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