| nonpenetrance | The state in which a genetic trait, although present in the appropriate genotype (i.e., homozygous, hemizygous, or heterozygous according to the state of dominance and mode of inheritance), fails to manifest itself in the phenotype because of nongenetic mechanisms. Compare: hypostasis. (05 Mar 2000) |
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| nonpenetrance |
The state in which a genetic trait, although present in the appropriate genotype, fails to manifest itself in the phenotype (eg, a woman with a BRCA1 mutation who lives to be elderly and never develops breast or ovarian cancer).
Ãâó: www.stjude.org/glossary
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| nonpenetrance |
Lack of clinical expression of the mutant phenotype in an individual with the appropriate genotype.
Ãâó: www.kumc.edu/gec/gloss.html
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