| macrocytosis | <haematology> Macrocytosis is enlargement of the red blood cells as defined by a red cell mean corpuscular volume (MCV) of greater than 100 fl. Macrocytosis is present in 1 to 4 % of the adult population. The most common cause is alcoholism. Other causes include: nutritional deficiencies (B12 and folate), chemotherapy, drug side effects, haemolysis, liver dysfunction, myelodysplasia and hypothyroidism. (27 Jan 1998) |
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