| 영문 | synapse | 한글 | 시냅스 |
|---|---|---|---|
| 설명 | 영국의 셰링턴(Sherrington)이 1897년 최초로 명명한 용어로써 신경세포인 뉴론과 뉴론이 만나는 곳을 의미함. 시냅스에는 화학물질의 유리에 의해 흥분을 전달하는 화학시냅스(chemical synapse)와 전기적으로 흥분이 직접 전달되는 전기 시냅스(electrical synapse)로 분류된다. 전기 시냅스는 시냅스전뉴론(presynaptic neuron)과 시냅스후뉴론(postsynaptic neuron)의 간격이 거의 없으며 전류가 쉽게 흐를 수 있는 낮은 저항의 gap junction을 형성하여 시냅스에서의 흥분전도가 일반적인 단일신경섬유나 동일세포내에서의 전기적 전도와 근본적으로 동일하다. 화학 시냅스는 시냅스전뉴론과 시냅스후뉴론사이에 약 20nm의 틈, 즉 시냅스간격(synaptic cleft)이 존재하며 전뉴론말단에는 전달물질을 내포하는 vesicle이 많이 존재하며, 시냅스전도시 전뉴론의 vesicle로부터 신경전달물질이 유리되어 확산에 의해 후뉴론의 수용체에 도달하여 결합한다. 이러한 신경전달물질의 유리에는 Ca 이온의 유입이 중요한 작용을 한다. |
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| SYN | synapse; synovitis |
|---|---|
| CAN'T | LEAP cyclosporine, alcohol, nicotinic acid, thiazides, lasix, ethambutanol, aspirin, pyrazinamide [s... |
| NA | Avogadro constant or number; nalidixic acid; Narcotics Anonymous; network administrator; neuraminida... |
| NAA | N-acetyl aspartate; naphthaleneacetic acid; neutral amino acid; neutron activation analysis; neutrop... |
| nAChR | nicotinic acetylcholine receptor |
| nAChR | Nicotinic ACh receptor |
|---|---|
| nACh | Nicotinic acetylcholine |
| nAChR | Nicotinic acetylcholine receptor |
| nAcChoR | nicotinic acetylcholine receptor |
| NA | Nicotinic acid |
| axoaxonic synapse | The synaptic junction between an axon terminal of one neuron and either the initial axon segment or an axon terminal of another nerve cell. (05 Mar 2000) |
|---|---|
| axodendritic synapse | The synaptic contact between an axon terminal of one nerve cell and a dendrite of another nerve cell. (05 Mar 2000) |
| axosomatic synapse | The synaptic junction of an axon terminal of one nerve cell to the cell body of another nerve cell. Synonym: pericorpuscular synapse. (05 Mar 2000) |
| receptors, nicotinic | One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for nicotine over muscarine. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, molecular biology, and biophysical properties of the channels. (12 Dec 1998) |
| rectifying synapse | <physiology> An electrical synapse at which current flow can only occur in one direction. (18 Nov 1997) |
| pericorpuscular synapse | The synaptic junction of an axon terminal of one nerve cell to the cell body of another nerve cell. Synonym: pericorpuscular synapse. (05 Mar 2000) |
| chemical synapse | <physiology> A nerve nerve or nerve muscle junction where the signal is transmitted by release from one membrane of a chemical transmitter that binds to a receptor in the second membrane. Importantly, signals only pass in one direction. (18 Nov 1997) |
| ribbon synapse | <biology, physiology> Ultrastructurally distinct type of synapse found in a variety of sensory receptor cells such as retinal photoreceptor cells, cochlear hair cells and vestibular organ receptors, as well as in a nonsensory neuron, the retinal bipolar cell. Unlike most neurons, these cells do not use regenerative action potentials but release transmitter in response to small graded potential changes. Ribbon synapses have different exocytotic machinery from conventional synapses in containing dense bars or ribbons anchored to the presynaptic membrane covered with a layer of synaptic vesices. The ribbons have been proposed to shuttle synaptic vesicles to exocytotic sites. (23 Aug 1998) |
| nicotinic | <chemistry> Pertaining to, or derived from, nicotine; nicotic; used specifically to designate an acid related to pyridine, obtained by the oxidation of nicotine, and called nicotinic acid. Source: Websters Dictionary (01 Mar 1998) |
| nicotinic acetylcholine receptor | Integral membrane protein of the postsynaptic membrane to which acetylcholine binds. The receptor contains an integral ion channel, as a result of binding of acetylcholine, ion channels in the subsynaptic membrane are opened. at the neuromuscular junction, the nicotinic acetylcholine receptor initiates muscle contraction. Currently the best characterised ion channel protein: made of a hetero pentamer of related subunits, although a homo pentamer is functional in insects. Structural studies show that the acetylcholine binding site and the ionic channel are part of the same macromolecular unit. The nAChR mediates rapid transduction events (1ms) whereas receptors activating G-protein coupled channels operate on slower time scales (millisecond to second range). (18 Nov 1997) |
| nicotinic acid | A precursor of NAD, that is a product of the oxidation of nicotine. (18 Nov 1997) |
| nicotinic acid amide | <biochemistry> Member of the water soluble B vitamin group, used in the production of fatty acids, steroids and cholesterol, deficiency is known as pellagra. Has cholesterol-lowering and vasodilating properties. (27 Sep 1997) |
| nicotinic acid maculopathy | Maculopathy observed in persons taking 3000 mg or more of nicotinic acid daily; normal vision returns after this medication is discontinued. (05 Mar 2000) |
| nicotinic acids | 2-, 3-, or 4-pyridinecarboxylic acids. Pyridine derivatives substituted with a carboxy group at the 2-, 3-, or 4-position. The 3-carboxy derivative (niacin) is active as a vitamin. (12 Dec 1998) |
| nicotinic agonists | Drugs that bind to and activate nicotinic cholinergic receptors (receptors, nicotinic). Nicotinic agonists act at postganglionic nicotinic receptors, at neuroeffector junctions in the peripheral nervous system, and at nicotinic receptors in the central nervous system. Agents that function as neuromuscular depolarising blocking agents are included here because they activate nicotinic receptors, although they are used clinically to block nicotinic transmission. (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|