| ¿µ¹® | receptor | ÇÑ±Û | ¼ö¿ëü |
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| ¿µ¹® | cholinergic | ÇÑ±Û | Äݸ°(ÀÛµ¿)¼º |
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| ¼³¸í | 1.½Å°æ¼¼Æ÷°¡ ´Ù¸¥ ½Å°æ¼¼Æ÷·Î Á¤º¸¸¦ Àü´ÞÇÒ °æ¿ì¿¡´Â ´ëºÎºÐ ÈÇй°ÁúÀ» ºÐºñÇÏ¿© ±×°ÍÀ» ¸Å°³·Î ÇÏ¿© ´Ù¸¥ ½Å°æ¿¡ Á¤º¸¸¦ Àü´ÞÇÑ´Ù. ÀÌ·± ¹°ÁúÀ» ½Å°æÀü´Þ¹°Áú¶ó°í ÇÑ´Ù. Äݸ°¼ºÀ̶õ ½Å°æÀü´Þ¹°Áú·Î acetylcholineÀ» »ç¿ëÇÏ´Â ½Å°æÀ» À̸£´Â ¸»ÀÌ´Ù. Áï ºÎ±³°¨½Å°æÀ» À̸£´Â ¸»·Î ¾²ÀδÙ. 2. Acetylcholine°ú À¯»çÇÑ ¾à¸®Àû ÀÛ¿ëÀ» ÇÏ´Â. |
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| nAChR | nicotinic acetylcholine receptor |
|---|---|
| CAN'T | LEAP cyclosporine, alcohol, nicotinic acid, thiazides, lasix, ethambutanol, aspirin, pyrazinamide [s... |
| NA | Avogadro constant or number; nalidixic acid; Narcotics Anonymous; network administrator; neuraminida... |
| NAA | N-acetyl aspartate; naphthaleneacetic acid; neutral amino acid; neutron activation analysis; neutrop... |
| NAD | neutrophil actin dysfunction; new antigenic determinant; nicotinamide adenine dinucleotide; nicotini... |
| nAChR | Nicotinic ACh receptor |
|---|---|
| nAChR | Nicotinic acetylcholine receptor |
| nAcChoR | nicotinic acetylcholine receptor |
| CBF | Cholinergic basal forebrain |
| HCNP | Hippocampal cholinergic neurostimulating peptide |
| nicotinic cholinergic receptor | A class of receptors responsive to acetylcholine that also are activated by nicotine; ganglionic (including the adrenal medulla) and neuromuscular receptors. Two classes exist: nicotinic-neuronal and nicotinic-muscular. (05 Mar 2000) |
|---|
| nicotinic acetylcholine receptor | Integral membrane protein of the postsynaptic membrane to which acetylcholine binds. The receptor contains an integral ion channel, as a result of binding of acetylcholine, ion channels in the subsynaptic membrane are opened. at the neuromuscular junction, the nicotinic acetylcholine receptor initiates muscle contraction. Currently the best characterised ion channel protein: made of a hetero pentamer of related subunits, although a homo pentamer is functional in insects. Structural studies show that the acetylcholine binding site and the ionic channel are part of the same macromolecular unit. The nAChR mediates rapid transduction events (1ms) whereas receptors activating G-protein coupled channels operate on slower time scales (millisecond to second range). (18 Nov 1997) |
|---|---|
| receptors, nicotinic | One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for nicotine over muscarine. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, molecular biology, and biophysical properties of the channels. (12 Dec 1998) |
| nicotinic | <chemistry> Pertaining to, or derived from, nicotine; nicotic; used specifically to designate an acid related to pyridine, obtained by the oxidation of nicotine, and called nicotinic acid. Source: Websters Dictionary (01 Mar 1998) |
| nicotinic acid | A precursor of NAD, that is a product of the oxidation of nicotine. (18 Nov 1997) |
| nicotinic acid amide | <biochemistry> Member of the water soluble B vitamin group, used in the production of fatty acids, steroids and cholesterol, deficiency is known as pellagra. Has cholesterol-lowering and vasodilating properties. (27 Sep 1997) |
| nicotinic acid maculopathy | Maculopathy observed in persons taking 3000 mg or more of nicotinic acid daily; normal vision returns after this medication is discontinued. (05 Mar 2000) |
| nicotinic acids | 2-, 3-, or 4-pyridinecarboxylic acids. Pyridine derivatives substituted with a carboxy group at the 2-, 3-, or 4-position. The 3-carboxy derivative (niacin) is active as a vitamin. (12 Dec 1998) |
| nicotinic agonists | Drugs that bind to and activate nicotinic cholinergic receptors (receptors, nicotinic). Nicotinic agonists act at postganglionic nicotinic receptors, at neuroeffector junctions in the peripheral nervous system, and at nicotinic receptors in the central nervous system. Agents that function as neuromuscular depolarising blocking agents are included here because they activate nicotinic receptors, although they are used clinically to block nicotinic transmission. (12 Dec 1998) |
| nicotinic alcohol | <chemical> 3-pyridinemethanol. A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. Pharmacological action: vasodilator agents. Chemical name: 3-Pyridinemethanol (12 Dec 1998) |
| nicotinic antagonists | Drugs that bind to nicotinic cholinergic receptors (receptors, nicotinic) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses. (12 Dec 1998) |
| nicotinic receptors | A class of cholinergic receptors on skeletal muscle cells that are linked to ion channels in the cell membrane. (05 Mar 2000) |
| receptors, cholinergic | Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behaviour of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology. (12 Dec 1998) |
| cholinergic | <pharmacology> Resembling acetylcholine in pharmacological action, stimulated by or releasing acetylcholine or a related compound. (15 Jan 1998) |
| cholinergic agent | An agent that mimics the action of the parasympathetic nervous system (e.g., methacholine). (05 Mar 2000) |
| cholinergic agents | Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of muscarinic agonist, although most modern texts discourage that usage. (12 Dec 1998) |
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