| NMB | neuromedin B; neuromuscular blockade; neuromuscular blocking; neuromuscular blocker/blocking [drug, ... |
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| NMT | neuromuscular tension; neuromuscular transmission; N-methyltransferase; N-myristoyltransferase; no m... |
| BB | bad breath; bed bath; beta blockade, beta blocker; BioBreeding [rat]; blanket bath; blood bank; bloo... |
| FNS | frontier nursing service; functional neuromuscular stimulation |
| FSN | functional stimulation, neuromuscular |
| NMB | Neuromuscular blockade |
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| CAB | Combined androgen blockade |
| MAB | Maximal androgen blockade |
| TAB | Total androgen blockade |
| AB | autonomic blockade |
| neuromuscular blockade | The intentional interruption of transmission at the neuromuscular junction by external agents, usually neuromuscular blocking agents. It is distinguished from nerve block in which nerve conduction is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce muscle relaxation as an adjunct to anaesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anaesthesia but is grouped here with anaesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here. (12 Dec 1998) |
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| adrenergic blockade | Selective inhibition by a drug of the responses of effector cells to adrenergic sympathetic nerve impulses (sympatholytic) and to epinephrine and related amines (adrenolytic). (05 Mar 2000) |
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| blockade | 1. Intravenous injection of large amounts of colloidal dyes or other substances whereby the reaction of the reticuloendothelial cells to other influences (e.g., by phagocytosis) is temporarily prevented. 2. Arrest of peripheral nerve conduction or transmission at autonomic synaptic junctions, autonomic receptor sites, or myoneural junctions by a drug. (05 Mar 2000) |
| ganglionic blockade | Inhibition of nerve impulse transmission at autonomic ganglionic synapses by drugs such as nicotine or hexamethonium. (05 Mar 2000) |
| virus blockade | The interference of one virus by another, either attenuated or unrelated. (05 Mar 2000) |
| cholinergic blockade | Inhibition by a drug of nerve impulse transmission at autonomic ganglionic synapses (ganglionic blockade), at postganglionic parasympathetic effector cells (e.g., by atropine), and at myoneural junctions (myoneural blockade), the inhibition of a cholinergic agent. (05 Mar 2000) |
| myoneural blockade | Inhibition of nerve impulse transmission at myoneural junctions by a drug such as curare. (05 Mar 2000) |
| narcotic blockade | The use of drugs to inhibit the effects of narcotic substances, as with naloxone. (05 Mar 2000) |
| sympathetic blockade | Interruption of transmission in sympathetic ganglia or conduction of impulses in pre-or postganglionic sympathetic nerve fibres. (05 Mar 2000) |
| neuromuscular | <anatomy> Pertaining to muscles and nerves. (18 Nov 1997) |
| neuromuscular agents | Drugs used for their actions on skeletal muscle. Included are agents that act directly on skeletal muscle, those that alter neuromuscular transmission (neuromuscular blocking agents), and drugs that act centrally as skeletal muscle relaxants (muscle relaxants, central). Drugs used in the treatment of movement disorders are anti-dyskinesia agents. (12 Dec 1998) |
| neuromuscular blocking agent | A group of drugs that prevent motor nerve endings from exciting skeletal muscle. They act either by competing for the neurotransmitter, acetylcholine, (like D-tubocurarine, mivacurium and pancuronium), or by first stimulating the postjunctional muscle membrane and subsequently desensitizing the muscle endplates to the acetylcholine (like succinylcholine or decamethonium); used in surgery to produce paralysis and facilitate manipulation of muscles. (05 Mar 2000) |
| neuromuscular blocking agents | Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (neuromuscular nondepolarising agents) or noncompetitive, depolarising agents (neuromuscular depolarising agents). Both prevent acetylcholine from triggering the muscle contraction and they are used as anaesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc. (12 Dec 1998) |
| neuromuscular cell | A cell of a lower metazoan organism that is both sensitive and contractile. (05 Mar 2000) |
| neuromuscular depolarising agents | Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarisation of the motor end plate. These agents are primarily used as adjuvants in surgical anaesthesia to cause skeletal muscle relaxation. (12 Dec 1998) |
| neuromuscular junction | A chemical synapse between a motoneuron and a muscle fibre. Synonym: motor end plate. (18 Nov 1997) |
Synonyms : Neuromuscular Block, Block, Neuromuscular, Blockade, Neuromuscular
| neuromuscular blockade |
a failure in neuromuscular transmission that can be induced pharmacologically or may result from pathological disturbance at the myoneural junction.
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