| 영문 | neurofibromatosis | 한글 | 신경섬유종증 |
|---|---|---|---|
| 설명 | 전신의 여러곳에 무더기로 나는 신경섬유종을 특징으로 하는 유전성 전신 병. 말초 신경뿐 아니라 중추 신경계도 침범할 수 있다. 신경섬유종은 주로 전신의 피부에 발생되지만 신경얼기 혹은 내장에 생기는 수도 있다. 피부에는 또한 곳곳에 특유의 갈색색소반을 보게 된다. 골격의 변형을 일으킬 수도 있다. 신경초종이나 악성신경초종, 더욱이 신경교종이나 수막종 등의 두개내종양을 합병함도 알려져 있다. 1형(von Recklinghausen 병, 전형적 신경섬유종증)과 2형(중추형 또는 청각신경섬유종증)으로 구분한다. 전형적 신경섬유종증(1형)이 가장 많이 발생하며 다음과 같은 3가지 소견을 보인댜. 즉 ① 체표면, 체내 여러 곳에 산재되어 발생하는 얼기모양신경종, ② 우유커피반점, ③ 리쉬(Lisch) 결절로 불리는 홍채의 착색과오종이다. 2형은 1형보다 발생빈도가 적고, 특징적으로 양쪽성 청각신경종이 있으며, 우유반점은 보이나 리쉬결절은 없다. |
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| NAME Syndrome | Nevi, Atrial myxoma, Myxoid neurofibroma, Ephelides Syndrome |
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| NAME | National Association of Medical Examiners; nevi, atrial myxoma, myxoid neurofibroma, ephelides [synd... |
| NF | neurofibroma |
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| neurofibroma | <oncology, tumour> A neurofibroma is a smooth, polypoid, soft or firm tumour that arises from the Schwann cells and fibroblasts of the neurilemmal sheath. They may grow anywhere in the myelinated nervous system. (27 Sep 1997) |
|---|---|
| neurofibroma, plexiform | A type of neurofibroma representing an anomaly rather than a true neoplasm, in which the proliferation of schwann cells occurs from the inner aspect of the nerve sheath, thereby resulting in an irregularly thickened, distorted, tortuous structure. In some instances the process extends along the course of the nerve and may eventually involve the spinal roots and the spinal cord. (12 Dec 1998) |
| neurofibromatosis | <oncology> One of the most common disorders in genetics, neurofibromatosis encompasses at least two diseases, designated NF-1 and NF-2. NF-1 or classic neurofibromatosis, is characterised by the familiar cafe- au-lait spots, axillary freckling, cutaneous and visceral neurofibromas (which sometimes undergo malignant transformation), gliomas, scoliosis, and Lisch nodules of the iris. NF-1 is associated with the the von Recklinghausen Neurofibromatosis locus that encodes the NF-1 protein, a GTPase activating protein which interacts with the ras proteins. The gene is located on chromosome 17. NF-2, also called acoustic or central neurofibromatosis, features neurofibromas restricted to the acoustic nerve (usually bilateral) and the central nervous system, skin lesions may or may not be present. The gene is located on chromosome 22. There are no biochemical markers of the disorder, but the cloning of both the NF-1 and NF-2 genes makes DNA-based diagnosis possible in some families. Both genes appear to be tumour suppressor genes. Both conditions are autosomal dominant, but the variable penetrance and expressivity and high frequency of new mutations make genetic counseling difficult. Inheritance: autosomal dominant. (29 Dec 1997) |
| neurofibromatosis 1 | A congenital autosomal dominant disorder characterised by developmental changes in the nervous system, muscles, bones, and skin especially in those derived from the embryonic neural crest. There are multiple cutaneous tumours and tumours of the peripheral and central nervous system. The disease has been linked to mutations of the nf1 gene on chromosome 17. (12 Dec 1998) |
| neurofibromatosis 2 | Severe autosomal dominant disorder characterised especially by bilateral acoustic neuromas as well as other multiple tumours including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the nf2 gene on chromosome 22. (12 Dec 1998) |
| storiform neurofibroma | An uncommon variant of dermatofibrosarcoma protuberans containing heavily pigmented dendritic melanocytes scattered between spindle cells of the tumour. Synonym: Bednar tumour, storiform neurofibroma. (05 Mar 2000) |
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Synonyms : Neurofibromas
Synonyms : Tumor Royale, Elephantiasis Neuromatoses, Neurofibromas, Plexiform, Neuroma, Plexiform, Pachydermatoceles, Plexiform Neurofibroma, Plexiform Neurofibromas, Plexiform Neuroma, Plexiform Neuromas
Synonyms : Multiple Neurofibromas, Neurofibromatosis 3, Neurofibromatosis Syndrome, Multiple Neurofibroma, Neurofibroma, Multiple, Neurofibromas, Multiple, Neurofibromatosis 3s, Neurofibromatosis Syndromes, Syndrome, Neurofibromatosis, Syndromes, Neurofibromatosis
Synonyms : NF1 (Neurofibromatosis 1), Neurofibromatosis I, Neurofibromatosis Type 1, Neurofibromatosis Type I, Neurofibromatosis, Peripheral, NF 1, Neurofibromatosis, Peripheral, NF1, Neurofibromatosis, Type 1, Neurofibromatosis, Type I, Recklinghausen's Disease of Nerve
Synonyms : Bilateral Acoustic Neurofibromatosis, Familial Acoustic Neuromas, NF2 (Neurofibromatosis 2), Neurofibromatosis II, Neurofibromatosis Type 2, Neurofibromatosis Type II, Neurofibromatosis, Central NF2, Neurofibromatosis, Central, NF 2, Neurofibromatosis, Type 2
| neurofibroma |
tumor of the fibrous covering of a peripheral nerve
출처: wordnet.princeton.edu/perl/webwn
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| neurofibromatosis |
autosomal dominant disease characterized by numerous neurofibromas and by spots on the skin and often by developmental abnormalities
출처: wordnet.princeton.edu/perl/webwn
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| neurofibroma |
A benign tumor that develops from the cells and tissues that cover nerves.
출처: www.stjude.org/glossary
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| neurofibromatosis |
a disease characterized by the growth of tumors (abnormal tissue growths) on various nerves in the body. The effects of these tumors vary, from going unnoticed to causing serious disability.
출처: https://www.healthforums.com/library/1,1277,articl...
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| neurofibromatosis |
A genetic condition that affects the nervous system, muscles, bones and skin.
출처: www.cnn.com/HEALTH/library/BN/00023.html
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| neurofibroma | tumor of the fibrous covering of a peripheral nerve |
|---|---|
| neurofibroma | autosomal dominant disease characterized by numerous neurofibromas and by spots on the skin and often by developmental abnormalities |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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