| CPM | Central Pontine Myelinolysis |
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| EPM | Extra Pontine Myelinolysis |
| myelinolysis | Dissolution of the myelin sheaths of nerve fibres. Origin: myelin + G. Lysis, dissolution (05 Mar 2000) |
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| myelinolysis, central pontine | A form of massive demyelination of the pons occurring in malnutrition and alcoholism. The remarkable unsystematic dissolution of the sheaths of medullated fibres is its most certain feature. The lesion varies from only a few millimeters in diameter to almost the entire pons. The basic pathology is the destruction of the medullated sheaths throughout the lesions with relative sparing of the axis cylinders and intactness of the nerve cells of the pontine nuclei. Pathologically it is easily differentiated from infarction and the inflammatory demyelinations of multiple sclerosis and postinfectious encephalomyelitis. There does not appear to be a genetic, sex, or age factor. It is often, however, associated with some other serious disease, particularly chronic alcoholism. (adams & victor, principles of neurology, 2d ed, p720) (12 Dec 1998) |
| central pontine myelinolysis | <neurology> A condition characterised by damage to the myelin (sheath) layer of nerve cells in the pons (brainstem). The destruction of myelin inhibits the conduction of a nerve impulse along a nerve cell. The most common cause for exacerbating this condition is a rapid correction of hyponatraemia (low blood sodium level). Some conditions such as Wernicke-Korsakoff syndrome and alcoholism can predispose to loss of myelin. Symptoms can include weakness, double vision, muscle spasms, speech difficulty, delirium, sleepiness, hallucinations, tremors and uncontrolled eye movements. An MRI scan of the brain can demonstrate the abnormality. A more slow controlled correction of serum sodium levels is necessary in these patients. There is no definitive treatment for the underlying disorder. (12 Jan 1998) |
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Synonyms : Extrapontine Myelinoclasis, Myelinoclasis, Central Pontine, Pontine Myelinolysis, Central, Central Pontine Myelinoclasis, Extrapontine Myelinoclases, Extrapontine Myelinolyses, Myelinoclases, Extrapontine, Myelinoclasis, Extrapontine
| myelinolysis |
demyelination.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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