| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
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| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| HGMCR | human genetic mutant cell repository |
|---|---|
| hr | hairless [mouse]; host-range [mutant]; hour |
| MH | malignant histiocytosis; malignant hyperpyrexia; malignant hypertension; malignant hyperthermia; mam... |
| CGRP | Calcitonin Gene Related Peptide(Protein) |
| CGRPs | Calcitonin Gene-Related Products |
| m | Mutant |
|---|---|
| mt | Mutant |
| MASA | Mutant allele specific amplification |
| MFs | Mutant frequencies |
| MF | Mutant frequency |
| mutant gene | A gene that has been changed from an ancestral type, not necessarily in the current generation. See: mutant, mutation. (05 Mar 2000) |
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| active mutant | A mutant with overt phenotypic expression. (05 Mar 2000) |
|---|---|
| amber mutant | A mutant with a mutation resulting in a UAG codon. (05 Mar 2000) |
| auxotrophic mutant | Mutant with a nutritional requirement not present in the wild type organism. Synonym: defective organism, deficiency mutant. (05 Mar 2000) |
| gap mutant | <molecular biology> A fruit fly of the genus Drosophila which is missing a number of adjacent segments because the segments failed to develop. (09 Oct 1997) |
| rats, mutant strains | Rats bearing mutant genes which are phenotypically expressed in the animals. (12 Dec 1998) |
| virulent phage mutant | A mutant of a phage that is unable to establish lysogeny. (05 Mar 2000) |
| relaxed mutant | A mutant bacterium that continues to synthesise RNA in a medium that lackscertain nutrients or amino acids which that sort of bacterium normallyneeds present before it can make RNA. (09 Oct 1997) |
| ced mutant | <organism> Giant multinucleate fresh water amoeba (up to 5mm long) much used for studies on the mechanism of cell locomotion. (18 Nov 1997) |
| cell division cycle mutant | A yeast cell which has cell division cycle genes that have mutated to become sensitive to temperature, at certain temperatures (usually high ones), various parts of the normal yeast cell cycle become abnormal, and in some strains the yeast cell does not survive at all. (09 Oct 1997) |
| petite mutant | <molecular biology, organism> A class of yeast mutants, most studied in Saccharomyces cerevisiae. Mutants grow slowly and rely on anaerobic respiration: mitochondria, although present, have reduced cristae and are functionally defective (termed promitochondria). There are three types of petite mutant: (i) Segregational mutants that show Mendelian behaviour and result from mutations in mitochondrial genes located in the nucleus. (ii) Neutral petites, which are recessive genotypes and result from the complete absence of mitochondrial DNA. (iii) Suppressive petites, in which most of the mitchondrial DNA is lost (60-99%), though what remains is often amplified. (06 Oct 1997) |
| mice, mutant strains | Mice bearing mutant genes which are phenotypically expressed in the animals. (12 Dec 1998) |
| minute mutant | <genetics, molecular biology> A class of recessive lethal mutants of Drosophila The heterozygotes grow more slowly, are smaller and less fertile than the wild type flies. There are about 40 loci that produce minute mutants. (18 Nov 1997) |
| cold-sensitive mutant | A mutant that is defective at low temperature but functional at normal temperature. Compare: temperature-sensitive mutant. (05 Mar 2000) |
| conditional-lethal mutant | A viral mutant that can replicate under some (permissive) conditions but not under other (restrictive or nonpermissive) conditions, the parent (wild type) strain being able to replicate under both conditions. See: suppressor-sensitive mutant, temperature-sensitive mutant. Synonym: conditional-lethal mutant. (05 Mar 2000) |
| conditionally lethal mutant | A viral mutant that can replicate under some (permissive) conditions but not under other (restrictive or nonpermissive) conditions, the parent (wild type) strain being able to replicate under both conditions. See: suppressor-sensitive mutant, temperature-sensitive mutant. Synonym: conditional-lethal mutant. (05 Mar 2000) |
| mutant gene |
a gene that has changed so that the normal transmission and expression of a trait is affected
출처: wordnet.princeton.edu/perl/webwn
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|---|---|
| mutant gene |
A form of gene changed over time that may or may not be present in the current population. b
출처: www.mise.org/mise/index.jsp
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| mutant gene | a gene that has changed so that the normal transmission and expression of a trait is affected |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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