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muscarin <physiology> A solid crystalline substance, C5H13NO2, found in the toadstool (Agaricus muscarius), and in putrid fish. It is a typical ptomaine, and a violent poison.
Source: Websters Dictionary
(01 Mar 1998)
muscarine Toxin (alkaloid) from the mushroom Amanita muscaria (Fly Agaric) that binds to (muscarinic) acetylcholine receptors.
(18 Nov 1997)
muscarinic 1. Having a muscarine-like action, i.e., producing effects that resemble postganglionic parasympathetic stimulation.
2. An agent that stimulates the postganglionic parasympathetic receptor.
See: muscarine, nicotinic.
(05 Mar 2000)
muscarinic acetylcholine receptor Distinct from the nicotinic ACh receptor in having no intrinsic ion channel, the receptor is formed from one protein chain with 7 transmembrane regions. The receptors produce their effect via activation of GTP-binding proteins.
(18 Nov 1997)
muscarinic agonist Drugs that bind to and activate muscarinic cholinergic receptors (receptors, muscarinic). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.
(12 Dec 1998)
muscarinic antagonist Drugs which bind with muscarinic cholinergic receptors but do not activate them, thus preventing access to acetylcholine; examples include atropine, scopolamine, propantheline, and pirenzepine.
(05 Mar 2000)
muscarinic antagonists Drugs that bind to but do not activate muscarinic cholinergic receptors (receptors, muscarinic), thereby blocking the actions of endogenous acetycholine or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. Antagonists that discriminate among the various muscarinic receptor subtypes and might allow better control of peripheral and central actions are under development.
(12 Dec 1998)
muscarinic receptor kinase <enzyme> Phosphorylates muscarinic acetylcholine receptors and beta-adrenergic receptors
Registry number: EC 2.7.-
Synonym: muscarinic acetylcholine receptor kinase, machr kinase
(26 Jun 1999)
muscarinic receptors Membrane-bound proteins whose extracellular domain contains a recognition site for acetylcholine (ACh); combination of Ach with the receptor initiates a physiologic change (slowing of heart rate, increased glandular secretory activity and stimulation of smooth muscle contractions); changes are observed after treatment with the mushroom alkaloid, muscarine. Muscarinic receptors are to be distinguished from nicotinic receptors.
(05 Mar 2000)
muscarinism Mushroom poisoning, characterised by gastrointestinal upset, liver andkidney damage, central nervous system effects and damage, and possiblydeath.
(09 Oct 1997)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 3 ÆäÀÌÁö: 1
  • Muscarine - »õâ A toxic alkaloid found in Amanita muscaria (fly fungus) and other fungi of the Inocybe species. It is the first parasympathomimetic substance ever studied and causes profound parasympathetic activation that may end in convulsions and death. The specific antidote is atropine.
    Synonyms :
  • Muscarinic Agonists - »õâ Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.
    Synonyms : Cholinergic Agonist, Muscarinic, Muscarinic Agonist, Agonist, Muscarinic, Agonist, Muscarinic Cholinergic, Agonists, Muscarinic, Agonists, Muscarinic Cholinergic, Muscarinic Cholinergic Agonist, Muscarinic Cholinergic Agonists
  • Muscarinic Antagonists - »õâ Drugs that bind to but do not activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC), thereby blocking the actions of endogenous acetylcholine or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. Antagonists that discriminate among the various muscarinic receptor subtypes and might allow better control of peripheral and central actions are under development.
    Synonyms : Agents, Antimuscarinic, Antagonists, Muscarinic
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muscarinism (mus
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
muscarine (mus
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
muscarine Muscarine, L-(+)-muscarine, or muscarin is a natural product found in certain mushrooms, particularly in Inocybe and Clitocybe species. It was first isolated from Amanita muscaria in 1869. It was the first parasympathomimetic substance ever studied and causes profound activation of the peripheral parasympathetic nervous system that may end in convulsions and death. ...
Ãâó: en.wikipedia.org/wiki/Muscarine
muscarine toxic quaternary ammonium compound found in species of Clitocybe and Inocybe; causes perspiration-salivation-lacrymation syndrome.
Ãâó: www.mycolog.com/GLOSSARY.htm
muscarinic A type of ACh receptor activated by muscarine that is coupled by a G-protein to intracellular messenging systems.
Ãâó: www.ualberta.ca/~neuro/OnlineIntro/glossary.htm
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