| MDR | median duration of response; medical device reporting; minimum daily requirement; multidrug resistan... |
|---|---|
| MDR | TB multidrug-resistant tuberculosis |
| MRP | mean resisting potential; medical reimbursement plan; multidrug resistance-associated protein |
| MRP | Multidrug Resistance Protein |
|---|---|
| MRP1 | Multidrug Resistance Protein 1 |
| MRP | Multidrug Resistance associated Protein |
| MDR 1 | Multidrug Resistance gene |
| MRP(1) | Multidrug Resistance-Associated protein |
| multidrug resistance | The insensitivity of various tumours to a variety of chemically related anticancer drugs; mediated by a process of inactivating the drug or removing it from the target tumour cells. (05 Mar 2000) |
|---|---|
| multidrug transporter | Closely related family (ABC transporters) of integral membrane glycoproteins that export a variety of solutes from the cytoplasm. (18 Nov 1997) |
| tuberculosis, multidrug-resistant | Tuberculosis resistant to chemotherapy with two or more antitubercular agents. The problem of resistance is particularly troublesome in tuberculosis as an opportunistic disease in HIV infection. (12 Dec 1998) |
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Synonyms : ATP-Binding Cassette, Sub-Family C Proteins, MOAT Protein, Multispecific Organic Anion Transport Proteins, Multispecific Organic Anion Transporter, ATP Binding Cassette, Sub Family C Proteins, Multidrug Resistance Associated Protein
| multidrug resistance |
Adaptation of tumor cells to anticancer drugs in ways that make the drugs less effective.
Ãâó: www.stjude.org/glossary
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| multidrug resistance |
Adaptation of tumor cells to chemotherapy by eliminating the drugs faster or breaking them down so that they are no longer effective.
Ãâó: nydailynews.healthology.com/nydailynews/15836.htm
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| multidrug resistance |
A characteristic of cells that makes them resistant to the effects of several different classes of drugs. There are several forms of drug resistance.They each are determined by genes that govern how the cell will respond to the chemical agents. One type of multidrug resistance (or MDR) involves the ability to eject several drugs out of cells. The cell outer wall or membrane of the cell contains a pump that ejects chemicals, preventing them from reaching a toxic concentration. ...
Ãâó: cll.ucsd.edu/glossarym.htm
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| multidrug resistance |
resistance of tumor cells to several unrelated drugs after exposure to a single chemotherapy drug.
Ãâó: www.cancer.org/docroot/GRY/GRY_0.asp
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| multidrug resistance |
Resistance of tumors or infectious agents to a wide-range of therapeutic compounds. In cancer multidrug resistance ABC-MDR proteins actively expel the cytotoxic drugs from cells, maintaining the drug level below a cell-killing threshold. Drug extrusion mediated by these primary active transporters is driven by the energy of ATP hydrolysis. The most intriguing characteristic distinguishing the ABC-MDR proteins from other mammalian transporters is their wide substrate specificity. ...
Ãâó: www.solvo.hu/glossary.html
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