| ¿µ¹® | chronic lymphocytic leukemia | ÇÑ±Û | ¸¸¼º¸²ÇÁ¼º ¹éÇ÷º´ |
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| ¼³¸í | ¹éÇ÷º´(leukemia)¶õ ºñÁ¤»óÀûÀÎ ¹éÇ÷±¸ ¼¼Æ÷ÀÇ Áõ½Ä¿¡ ÀÇÇØ ÀϾ´Â º´ÀûÀÎ »óŸ¦ ¸»Çϴµ¥, ÈçÈ÷ ¸»ÃÊÇ÷¾×¿¡ ¹ÌºÐȼ¼Æ÷°¡ ³ªÅ¸³ª¸ç, Á¤»óÀûÀÎ ÀûÇ÷±¸¼¼Æ÷¿Í ¹éÇ÷±¸¼¼Æ÷, Ç÷¼ÒÆÇÀÇ ±Þ°ÝÇÑ °¨¼Ò¸¦ °¡Á®¿Í Á¤»óÀûÀÎ ¼¼Æ÷¿¡ ÀÇÇØ ÇàÇØÁö´Â ¿©·¯ ±â´ÉÀÇ °¨¼Ò¸¦ ÁÖÁõ»óÀ¸·Î ÇÏ¿© º´¿ø¿¡ ã¾Æ¿À°Ô µÈ´Ù. µû¶ó¼ ÀûÇ÷±¸¼¼Æ÷ÀÇ °¨¼Ò·Î ÀÎÇÑ ºóÇ÷, ¹éÇ÷±¸¼¼Æ÷ÀÇ °¨¼Ò·Î ÀÎÇÑ ¸¹Àº °¨¿°Áõ¼¼(ÈçÈ÷ °É¸®Áö ¾Ê´Â ¼¼±Õ¿¡ ÀÇÇÑ °¨¿°, Áö³ªÄ¡°Ô ÀæÀº °¨±â, Æó·Å µî), Ç÷¼ÒÆÇ¼¼Æ÷ÀÇ °¨¼Ò·Î ÀÎÇÑ ÃâÇ÷Áõ»óÀÌ ³ªÅ¸³´Ù. ¶ÇÇÑ ÇǸ¦ »ý»êÇÏ´Â °ñ¼ö Á¶Á÷¿¡¼´Â ÀÌ·± ºñÁ¤»óÀûÀÎ ¼¼Æ÷ÀÇ Áõ½Ä¸¸À» º¼ ¼ö ÀÖÀ¸¸ç, Á¤»óÀûÀÎ ¼¼Æ÷ÀÇ Áõ½ÄÀº º¸±â Èûµé´Ù. ¸¸¼º¸²ÇÁ¼º ¹éÇ÷º´Àº ¼¾ç¿¡¼´Â ºñ±³Àû ¹éÇ÷º´ Áß¿¡¼ ÈçÇÑ ÇüÀÌÁö¸¸ µ¿¾ç±Ç¿¡¼´Â ¾ÆÁÖ µå¹® ¹éÇ÷º´ÀÇ ÇüÅÂÀÌ´Ù. ´ë°³ 60¼¼ ÀÌ»óÀÇ °í·ÉÃþ¿¡¼ ¸¹ÀÌ »ý±â°í 30¼¼ ÀÌÇÏ¿¡¼´Â °ÅÀÇ Ã£¾Æº¼ ¼ö°¡ ¾ø´Ù. Ç÷¾×°Ë»ç»ó¿¡¼ ¸²ÇÁ±¸ÀÇ ¸¹Àº Áõ°¡¸¦ º¼ ¼ö°¡ ÀÖ°í, ´ë½Å¿¡ ´Ù¸¥ Ç÷¾×¼¼Æ÷µéÀº °¨¼Ò¸¦ ³ªÅ¸³½´Ù. ¹éÇ÷º´ Áß ¿¹Èİ¡ ÁÁÀº ÆíÀÌ¸ç ´ë°³ Ä¡·á´Â Ç×¾ÏÁ¦¸¦ ÀÌ¿ëÇÑ ÈÇпä¹ýÀ» ¸¹ÀÌ »ç¿ëÇϸç, Æò±Õ »ýÁ¸±â°£Àº 4~5³âÀÌ´Ù. |
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| ¿µ¹® | leukemia | ÇÑ±Û | ¹éÇ÷º´ |
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| ¼³¸í | ºñÁ¤»óÀûÀÎ ¹éÇ÷±¸ ¼¼Æ÷ÀÇ Áõ½Ä¿¡ ÀÇÇØ ÀϾ´Â º´ÀûÀÎ »óŸ¦ ¸»Çϴµ¥, ÈçÈ÷ ¸»ÃÊ Ç÷¾×¿¡ ¹ÌºÐȼ¼Æ÷°¡ ³ªÅ¸³ª¸ç, Á¤»óÀûÀÎ ÀûÇ÷±¸¼¼Æ÷¿Í ¹éÇ÷±¸¼¼Æ÷, Ç÷¼ÒÆÇÀÇ ±Þ°ÝÇÑ °¨¼Ò¸¦ °¡Á®¿Í Á¤»óÀûÀÎ ¼¼Æ÷¿¡ ÀÇÇØ ÇàÇØÁö´Â ¿©·¯ ±â´ÉÀÇ °¨¼Ò¸¦ ÁÖÁõ»óÀ¸·Î ÇÏ¿© º´¿ø¿¡ ã¾Æ¿À°Ô µÈ´Ù. µû¶ó¼ ÀûÇ÷±¸ ¼¼Æ÷ÀÇ °¨¼Ò·Î ÀÎÇÑ ºóÇ÷, ¹éÇ÷±¸¼¼Æ÷ÀÇ °¨¼Ò·Î ÀÎÇÑ ¸¹Àº °¨¿°Áõ¼¼(ÈçÈ÷ °É¸®Áö ¾Ê´Â ¼¼±Õ¿¡ ÀÇÇÑ °¨¿°, Áö³ªÄ£ ÀæÀº °¨±â, Æó·Å µî), Ç÷¼ÒÆÇ¼¼Æ÷ÀÇ °¨¼Ò·Î ÀÎÇÑ ÃâÇ÷Áõ»óÀÌ ³ªÅ¸³´Ù. ¶ÇÇÑ ÇǸ¦ »ý»êÇÏ´Â °ñ¼ö Á¶Á÷¿¡¼´Â ÀÌ·± ºñÁ¤»óÀûÀÎ ¼¼Æ÷ÀÇ Áõ½Ä¸¸À» º¼ ¼ö ÀÖÀ¸¸ç, Á¤»óÀûÀÎ ¼¼Æ÷ÀÇ Áõ½ÄÀº º¸±â Èûµé´Ù. ÀÌ·± ¹éÇ÷º´¿¡´Â ¿©·¯ °¡Áö°¡ ÀÖ´Â µ¥ Å©°Ô 4°¡Áö·Î ³ª´©¾î ºÐ·ùÇÑ´Ù. Á¤»óÀûÀ¸·Î ¹éÇ÷±¸¼¼Æ÷´Â ¸²ÇÁ°è¼¼Æ÷¿Í °ñ¼ö°è¼¼Æ÷·Î 2ºÐµÇ´Âµ¥, ¹éÇ÷º´ ¶ÇÇÑ ÀÌ·± ¸²ÇÁ°è¼¼Æ÷ÀÇ Áõ½Ä°ú °ñ¼ö°è¼¼Æ÷ÀÇ Áõ½Ä¿¡ µû¶ó ³ª´©¸ç, ±× Áõ»óÀÌ ¾ó¸¶³ª »¡¸® ³ªÅ¸³ª´Â °¡¿¡ µû¶ó ¸¸¼º, ±Þ¼ºÀ¸·Î ³ª´«´Ù. µû¶ó¼ ¿©±â¿¡´Â ´ÙÀ½ 4°¡ÁöÀÇ ºÐ·ù°¡ ³ª¿À°Ô µÈ´Ù. -±Þ¼º¸²ÇÁ¼º ¹éÇ÷º´: acute lymphocytic -±Þ¼º°ñ¼ö¼º ¹éÇ÷º´: acute myelogenous -¸¸¼º¸²ÇÁ¼º ¹éÇ÷º´: chronic lymphocytic -¸¸¼º°ñ¼ö¼º ¹éÇ÷º´: chronic myelogenous. |
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| ¿µ¹® | virus | ÇÑ±Û | ¹ÙÀÌ·¯½º |
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| ¼³¸í | ¹ÚÅ׸®¾Æº¸´Ù ´ú ÁøÈµÈ, »ý¹°°ú ¹«»ý¹°ÀÇ Áß°£´Ü°è¿¡ ÇØ´çÇÏ´Â °Í. È¥ÀÚ¼´Â »ýÁ¸´É·ÂÀÌ ¾øÀ¸¹Ç·Î ¹Ýµå½Ã ´Ù¸¥ ¼¼Æ÷³»¿¡ ¼ÓÇØ ÀÖ¾î¾ß ÇÑ´Ù. ÀÎü¿¡ ¹ß»ýÇÏ´Â ¸¹Àº º´Áß, ÀÌ ¹ÙÀÌ·¯½º·Î ÀÎÇØ ¹ß»ýÇÏ´Â °æ¿ì°¡ ¸¹À¸¸ç, ÀÌ ¶§ ´ëºÎºÐ ƯÀÌÇÑ Ä¡·á¹ýÀº ¾ø´Â ½ÇÁ¤ÀÌ´Ù. ÀϺΠÇ츣Æä½º¹ÙÀÌ·¯½º °èÅë¿¡´Â Ä¡·á¾àÀÌ °³¹ßµÇ¾î ÀÖÁö¸¸, À̰͵µ ÀϺΠÁúº´¿¡¼¸¸ Ä¡·á°¡ °¡´ÉÇÏ´Ù. ¶ÇÇÑ, Ebstein-Barr virus, Human papilloma virus µîÀº ¾ÏÀÇ ¹ß»ý°ú ¿¬°üµÇ¾î ÀÖÀ¸¸ç, µ¿¹°¿¡¼ ¹ß»ýÇÏ´Â ´ëºÎºÐÀÇ ¾ÏÁ¾Àº ¹ÙÀÌ·¯½º¿Í ¿¬°üµÇ¾î ÀÖ´Â °æ¿ì°¡ ¸¹´Ù. ¿äÁò, ÀϺΠÁö¿ª¿¡¼ Å« À¯ÇàÀ» Çϰí ÀÖ´Â ÈÄõ¼º¸é¿ª°áÇÌÁõÈıº(AIDS)µµ HIV(Human Immunodeficiency Virus)¿Í °ü·ÃÀÌ ÀÖ´Ù. |
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| ¿µ¹® | simian virus | ÇÑ±Û | ¿ø¼þÀ̹ÙÀÌ·¯½º |
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| ¼³¸í | ¿ø¼þÀÌ¿¡¼ ºÐ¸®µÈ ¹ÙÀÌ·¯½º. ¾Æµ¥³ë¹ÙÀÌ·¯½º, ¿£Å׷ιÙÀÌ·¯½º, Ç츣Æä½º¹ÙÀÌ·¯½º ¹× ·¹¿À¹ÙÀÌ·¯½º µîÀÇ ¿©·¯ ±º¿¡ ¼ÓÇÑ´Ù. |
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| ¿µ¹® | influenza virus | ÇÑ±Û | ÀÎÇ÷翣ÀÚ¹ÙÀÌ·¯½º |
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| ¼³¸í | ÀÎÇ÷翣ÀÚÀÇ º´¿øÃ¼. »ó±âµµ Á¡¸·¿¡ ħÀÔÇÏ¿© È£Èí±â ÁúȯÀ» ÀÏÀ¸Å²´Ù. º¸Ã¼ °áÇÕ Ç׿øÀÇ Â÷ÀÌ¿¡ µû¶ó A-B-C ¼¼ÇüÅ·Π³ª´µ¸ç, À¯ÇàÇÒ ¶§¸¶´Ù Ç÷±¸ ÀÀÁý Ç׿øÀÌ º¯ÀÌÇÏ¿© ±¤¹üÀ§ÇÑ À¯ÇàÀ» ³ªÅ¸³½´Ù. ²®ÁúÀÌ ÀÖ´Â 80~150nmÀÇ °ø¸ð¾ç, ³ª¼± ´ëĪ RNA ¹ÙÀÌ·¯½ºÀÌ´Ù. µÎ Á¾·ùÀÇ ½ºÆÄÀÌÅ©, ´º¶ó¹Ì´Ï´Ù¾ÆÁ¦(neuraminidase, NA), ´ç´Ü¹éÁú°ú Ç츶±Û·çƼ´Ñ(hemagglution, HA) ´ç´Ü¹éÁúÀ» ¸¸µç´Ù. AÇüÀÇ NA¿¡´Â N1-N2ÀÇ µÎ Á¾·ù, HA¿¡´Â HAO-HA1-HA2-HA3ÀÇ ³× Á¾·ù°¡ ÀÖ´Ù. AÇüÀº ¸»-µÅÁö-»õ¿¡ °¨¿°ÇÏ¸ç »õ·Î¿î ¾ÆÇüÀº µ¿¹° ¹ÙÀÌ·¯½º¿ÍÀÇ Á¶È¯ÇüÀ̸ç, ±× ¹Û¿¡ µ¿ÀÏ ¾ÆÇü³» Á¡º¯À̰¡ ÀÖ´Ù. B, CÇüÀº »ç¶÷ À̿ܿ¡´Â °¨¿°µÇÁö ¾Ê´Â´Ù. ´ßÀÇ ÀûÇ÷±¸¸¦ ÀÀÁýÇÏ´Â ¼ºÁúÀÌ ÀÖ´Ù. ¹ÙÀÌ·¯½º Áø´Ü¿¡´Â ȯÀÚÀÇ ÀεΠ¼¼Ã´¾×¿¡¼ ºÐ¸®ÇѴٵ簡, ¶Ç´Â ȯÀÚÀÇ Ç÷ûÇ×ü¿¡ ÀÇÇÑ Æ¯ÀÌÀû ÀûÇ÷±¸ ÀÀÁýÀúÁö°Ë»ç, ´º¶ó¹Ì´Ï´Ù¾ÆÁ¦ Ȱ¼ºÀúÁö°Ë»ç ¶Ç´Â ÁßÈ°Ë»ç µîÀ¸·Î °ËÃâÇÑ´Ù. |
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| MLV | Moloney leukemia virus; multilaminar vesicle; murine leukemia virus |
|---|---|
| AmuLV | Abelson murine leukemia virus; amphotrophic murine leukemia virus |
| AML | Acute Myelogenous Leukemia Morphologic Classification(FABºÐ·ù) &n... |
| MML | Moloney murine leukemia; monomethyllysine; myelomonocytic leukemia |
| MMLV | Moloney murine leukemia virus |
| MoMLV | Moloney Murine Leukemia Virus |
|---|---|
| M-MuLV | Moloney Murine Leukemia Virus |
| MoMuLV | Moloney Murine Leukaemia virus |
| MoMSV | Moloney Murine Sarcoma Virus |
| M-MSV | Moloney murine sarcoma virus |
acute monocytic leukemia
| Moloney murine leukaemia virus | <molecular biology, virology> Replication competent retrovirus (Oncovirinae) that causes leukaemia in mice, isolated by Moloney from cell free extracts made from a transplantable mouse sarcoma. (18 Nov 1997) |
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| Moloney murine sarcoma virus | <molecular biology, virology> Replication defective retrovirus, source of the oncogene v mos, responsible for inducing fibrosarcomas in vivo and transforming cells in culture. (18 Nov 1997) |
| leukemia | <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved. (18 Nov 1997) |
| moloney leukaemia virus | A murine virus arising during the propagation of s37 mouse sarcoma, and causing lymphoid leukaemia in mice. It also infects rats and newborn hamsters and is apparently transmitted vertically to embryos in utero and through mother's milk. (12 Dec 1998) |
| moloney sarcoma virus | A replication-defective murine sarcoma virus (sarcoma viruses, murine) isolated from a rhabdomyosarcoma by moloney in 1966. (12 Dec 1998) |
| Moloney's virus | A lymphoid leukaemia retrovirus of mice, in the subfamily Oncovirinae, isolated originally during propagation of S 37 mouse sarcoma. (05 Mar 2000) |
| Abelson murine leukaemia virus | A retrovirus belonging to the Type C retrovirus group subfamily (family Oncovirinae) which is associated with leukaemia and produces in vitro transformation of mouse cells. (05 Mar 2000) |
| gastroenteritis virus, murine | A species of the coronavirus genus causing hepatitis in mice. Four strains have been identified as mhv 1, mhv 2, mhv 3, and mhv 4 (also known as jhm, which is neurotropic and causes disseminated encephalomyelitis with demyelination as well as focal liver necrosis). (12 Dec 1998) |
| murine leukaemia virus | <virology> A group of type C retroviruses infecting mice and causing in some strains lymphatic leukaemia after a long latent period. Nearly all are replication competemt and v onc minus. See: Abelson leukaemia virus. (18 Nov 1997) |
| murine sarcoma virus | A seemingly defective retrovirus that produces sarcomas in mice when growing in the presence of a "helper" virus; e.g., mouse leukaemia virus. (05 Mar 2000) |
| theiler's murine encephalomyelitis virus | A species of cardiovirus which causes poliomyelitis in rats. It should not be confused with the strain of encepalomyocarditis virus called encephalomyelitis virus, murine, which is also a cardiovirus. (12 Dec 1998) |
| encephalomyelitis virus, murine | A strain of encephalomyocarditis virus, a species of cardiovirus, usually causing an inapparent intestinal infection in mice. A small number of mice may show signs of flaccid paralysis. (12 Dec 1998) |
| Friend murine leukaemia virus | <virology> Murine leukaemia virus isolated by Charlotte Friend in 1956 whilst attempting to transmit the Erlich ascites tumour by cell free extracts. Causes an unusual erythroblastosis like leukaemia, in which anaemia is accompanied by large numbers of nucleated red cells in blood. does not carry a host derived oncogene, but seems to induce tumours by proviral insertion into specific regions of host genome. (18 Nov 1997) |
| Moloney, John | <person> 20th century U.S. Oncologist. See: Moloney's virus. (05 Mar 2000) |
| Moloney, Paul | <person> Canadian physician, 1870-1939. See: Moloney test. (05 Mar 2000) |
Synonyms : Leukemia Virus, Moloney, Virus, Moloney Leukemia
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