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"minimal lethal dose"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
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¿µ¹® radiation dose ÇÑ±Û ¹æ»ç¼±·®
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  ¹æ»ç¼±Á¶»çÀÇ Á¤µµ. ¹æ»ç¼±»ý¹°ÇÐÀ̳ª ÀÎüÀÇ ¹æ»ç¼±¹æÈ£¿¡¼­´Â Àü¸®¹æ»ç¼±ÀÇ ¾ç, Áï ¼±·®ÀÌ ¹®Á¦°¡ µÈ´Ù. ¹æ»ç¼±·®¿¡¼­µµ ±¹Á¦´ÜÀ§°è(SI)°¡ Ã¤¿ëµÇ¾î ±¹Á¦¹æ»ç¼±¹æÈ£À§¿øÈ¸(ICRP)ÀÇ ±Ç°í¿¡ µû¶ó¼­ ´ÙÀ½ÀÇ ¿©·¯ ´ÜÀ§°¡ ³Î¸® »ç¿ëµÈ´Ù. ¨ç Èí¼ö¼±·®(absorbed dose). ¹°ÁúÀÇ ´ÜÀ§Áú·®ÀÌ ¹æ»ç¼±¿¡ ÀÇÇØ ¹Þ¾ÆµéÀ̴ ¿¡³ÊÁö. ÀÌ ´ÜÀ§´Â ¹æ»ç¼± ¹× ¹°ÁúÀÇ Á¾·ù°¡ ¾î¶°ÇÑ °ÍÀÌ´õ¶óµµ »ç¿ëÇÒ ¼ö ÀÖ´Ù. ±¹Á¦´ÜÀ§´Â J/kgÀ̸ç À̰Ϳ¡ °íÀ¯ÇÑ ¸íĪÀ¸·Î ±×·¹ÀÌ(gray, ±âÈ£ Gy)°¡ ºÎ¿©µÈ´Ù. 1Gy=100¶óµå(rad). ¨è Á¶»ç¼±·®(exposure) ¶Ç´Â °øÁß¼±·®. X¼± ¶Ç´Â ¥ã¼±¿¡ ÇÑÇØ¼­ »ç¿ëµÈ´Ù. ±¹Á¦´ÜÀ§´Â C/kg. ¨é ¼±·®´ç·®(dose equivalent). ¹æ»ç¼±¹æÈ£¸¦ À§ÇØ »ç¿ëµÇ´Â ¾ç. ±âÈ£´Â H. H´Â ¹æ»ç¼±ÀÇ Á¾·ù¿Í ¿¡³ÊÁö¿¡ ÀÇÇØ »ýü¿¡ Áִ ȿ°ú¸¦ º¸Á¤Çϴ ¼±Áú°è¼ö(Q)¿Í ±× ¹ÛÀÇ ÀÎÀÚ(¿¹¸¦ µé¸é ¼±·®·ü, ¹æ»ç¼ºµ¿À§¿ø¼Ò¿¡ ÀÇÇÑ ³»ºÎÇÇÆø½Ã¿¡´Â ±× ÇÙÁ¾ÀǠü³»ºÐÆ÷ µî)¿¡ ±Ù°ÅÇÑ º¸Á¤°è¼ö(N)¸¦ Èí¼ö¼±·®(D)¿¡ °öÇÑ °Í, Áï H=D-Q-N. ¶ÇÇÑ DÀÇ ´ÜÀ§¸¦ Gy ¶Ç´Â rad·Î Ç¥½ÃÇÏ¿´À» ¶§ HÀÇ ´ÜÀ§¸¦ °¢°¢ ½Ãº£¸£Æ®(sievert, ±âÈ£ Sv) ¹× ·½(rem)À̶ó°í ÇÑ´Ù. µû¶ó¼­ 1 Sv=102rem. ÀϹÝÀûÀ¸·Î ´ÜÀ§½Ã°£´çÀÇ ¼±·®À» ¼±·®·ü(dose rate)À̶ó°í ÇÑ´Ù.
¿µ¹® dose ÇÑ±Û ¿ë·®, Åõ¿©·®, ¹æ»ç¼±·®
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  1. ¾àÁ¦¸¦ ÇÑ ¹ø ¶Ç´Â ÇÏ·ç¿¡ »ç¿ëÇϰųª º¹¿ëÇϴ ºÐ·®. 2. ¹°ÁúÀ̳ª Á¶Á÷¿¡ ´ëÇÑ ¹æ»ç¼±ÀÇ ÀÛ¿ë Á¤µµ¸¦ ³ªÅ¸³»´Â ¾ç. Áï, ¹æ»ç¼±·®À̶ó´Â °³³äÀº ¾î¶² ÇÑ Á¡¿¡ ÀÔ»çÇϴ ¹æ»ç¼±°ú ±× Á¡ ±Ùó¿¡ Àִ ¹°Áú¿¡ ´ëÇÑ ¹æ»ç¼±ÀÇ ¹°¸®Àû-È­ÇÐÀû-»ý¹°ÇÐÀû È¿°ú¿ÍÀÇ °ü°Ô¸¦ Á¤·®ÀûÀ¸·Î ³ªÅ¸³»´Â °øÅëÀΠôµµ·Î¼­ »ý°¢µÈ °ÍÀÌ´Ù. ¶óµå(rad)·Î ³ªÅ¸³»´Â Èí¼ö·®, ·»Æ®°Õ(R)À¸·Î ³ªÅ¸³»´Â Á¶»ç ¼±·®, ·½(rem)À¸·Î ³ªÅ¸³»´Â ¼±·® ´ç·®À¸·Î ±¸ºÐÇÏ¿© ¾´´Ù.
¿µ¹® skin dose ÇÑ±Û ÇǺμ±·®
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  1. ÇǺÎÇ¥¸é¿¡¼­ÀÇ ¹æ»ç¼±ÀÇ °øÁß¼±·®À¸·Î ¿©±â¿¡´Â 1Â÷¹æ»ç¼±°ú ÈĹæ»ê¶õÀÌ Æ÷ÇԵȴÙ. 2. ÇǺο¡ Èí¼öµÇ´Â ¼±·®.
´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • minimal lethal dose
    1. ÃÖ¼ÒÄ¡»ç·® 2. ÃÖ¼ÒÄ¡»ç¼±·®
´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • lethal dose
    1. Ä¡»ç¿ë·® 2. Ä¡»ç¼±·®
  • mean lethal dose
    1. Æò±ÕÄ¡»ç¿ë·® 2. Æò±ÕÄ¡»ç¼±·®
  • median lethal dose
    1. Áß°£Ä¡»ç¿ë·® 2. Áß°£Ä¡»ç¼±·®
  • minimal effective dose
    ÃÖ¼ÒÀ¯È¿·®
  • minimal erythema dose
    ÃÖ¼ÒÈ«¹Ý¼±·®
  • minimal infecting dose
    ÃÖ¼Ò°¨¿°¿ë·®
  • conditional lethal mutant
    Á¶°ÇÄ¡»çµ¹¿¬º¯ÀÌÁÖ
  • conditional lethal mutation
    Á¶°ÇÄ¡»çµ¹¿¬º¯ÀÌ
  • lethal
    Ä¡»ç-
  • lethal gene
    Ä¡»çÀ¯ÀüÀÚ
  • lethal midline granuloma
    Ä¡»çÁß°£¼±À°¾ÆÁ¾, Ä¡»çÁßÀ°¾ÆÁ¾
  • lethal titer test
    Ä¡»ç¿ª°¡°Ë»ç
  • minimal
    ÃÖ¼Ò-
  • minimal alveolar concentration
    ÃÖ¼ÒÆóÆ÷³óµµ
  • minimal anesthetic concentration
    ÃÖ¼Ò¸¶Ãë³óµµ
´ëÇÑÀÇÇù Çʼö ÀÇÇпë¾îÁý »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 14 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • lethal dose
    Ä¡»ç·®
  • minimal invasive surgery
    ÃÖ¼Òħ½À¼ö¼ú
  • dose
    ¿ë·®, Åõ¿©·®, ¹æ»ç¼±·®
  • average dose
    Æò±Õ¿ë·®, Æò±Õ¼±·®
  • booster dose
    Ãß°¡Á¢Á¾·®, Ãß°¡¿ë·®
  • effective dose
    À¯È¿¿ë·®, À¯È¿¼±·®
  • maximum dose
    ÃÖ´ë¿ë·®, ÃÖ´ë¼±·®
  • optimum dose
    ÀûÁ¤¿ë·®, ÀûÁ¤¼±·®
  • radiation dose
    ¹æ»ç¼±·®
  • radiation absorbed dose
    Èí¼ö¼±·®
  • skin dose
    ÇǺμ±·®
  • therapeutic dose
    Ä¡·á¿ë·®, Ä¡·á¼±·®
  • high-dose
    °í¿ë·®
  • dose-response relationship
    ¿ë·®¹ÝÀÀ°ü°è
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • minimal lethal dose
    ÃÖ¼ÒÄ¡»ç·®, ÃÖ¼ÒÄ¡»ç¼±·®
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • lethal dose
    Ä¡»ç¿ë·®, Ä¡»ç·®, Ä¡»ç¼±·®
  • mean lethal dose
    Æò±ÕÄ¡»ç·®, Æò±ÕÄ¡»ç¼±·®
  • median lethal dose
    Áß°£Ä¡»ç·®, Áß°£Ä¡»ç¼±·®
  • minimal effective dose
    ÃÖ¼ÒÀ¯È¿·®
  • minimal erytherma dose
    ÃÖ¼ÒÈ«¹Ý¼±·®
  • conditional lethal mutant
    Á¶°ÇÄ¡»çµ¹¿¬º¯ÀÌÁÖ
  • conditional lethal mutation
    Á¶°ÇÄ¡»çµ¹¿¬º¯ÀÌ
  • lethal gene
    Ä¡»çÀ¯ÀüÀÚ
  • lethal midline granuloma
    Ä¡»çÁ߽ɼ±À°¾ÆÁ¾
  • lethal
    Ä¡»ç-
  • lethal toxin
    Ä¡»çµ¶¼Ò
  • lethal titer test
    Ä¡»çÁ¤·®°Ë»ç
  • minimal visible angle
    Ãּҽð¢
  • minimal alveolar concentration
    ÃÖ¼ÒÆóÆ÷³»³óµµ
  • minimal anesthetic concentration
    ÃÖ¼Ò¸¶Ãë³óµµ
¿¾ ´ëÇÑÀÇÇù 2 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • LD = lethal dose
    Ä¡»ç·®.
  • LD50 (50% lethal dose)
    50% Ä¡»ç·®
  • LD= lethal dose
    Ä¡»ç·®.
  • half lethal dose
    ¹ÝÄ¡»ç·®(ÚâöÈÞÝåÖ).
  • Kobraks minimal stimulation
    ÄÚºê¶ô¾àÀڱعý
  • granuloma, lethal midline
    ¾Ç¼º Á߽ɼ± ¼º À°¾ÆÁ¾
  • ED 50=£¾effective dose 50%
    50% À¯È¿·®, Áß°£À¯È¿·®.
  • ED 50=£¾effective dose 50%
    50% À¯È¿·®.
  • ED 50=ÊÝeffective dose 50%
    50% À¯È¿·®.
  • ED=ÊÝeffective dose
    À¯È¿·®.
  • ID50 (50% infectious dose)
    50% °¨¿°·®
  • MED => minimum effective dose
    ÃÖ¼ÒÈ«¹Ý·®
  • MED=> minimum effective dose
    ÃÖ¼ÒÀ¯È¿·®.
  • MED=£¾minimum effective dose
    ÃÖ¼ÒÀ¯È¿·®.
  • MTD=> maximum toderance dose
    ÃÖ´ë³»¿ë·®.
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö ¸ÂÃã °Ë»ö °á°ú : 3 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • minimal lethal dose
    ÃÖ¼ÒÄ¡»ç·®(õÌá´öÈÞÝåÖ).
  • minimal lethal dose
    ÃÖ¼ÒÄ¡»ç·®(̧ËÛ̬Ë×Ëâ).
  • minimal lethal dose
    ÃÖ¼ÒÄ¡»ç·®(õÌá³öÈÞÝåÖ).
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • dose, lethal
    Ä¡»ç·®
  • half lethal dose
    ¹ÝÄ¡»ç·®(ÚâöÈÞÝåÖ).
  • lethal dose
    Ä¡»ç¼±·®
  • lethal dose
    Ä¡»ç·®
  • mean lethal dose =LD50
    50% Ä¡»ç·® (¡­öÈÞÝåÖ).
  • mean lethal dose, Do
    Æò±ÕÄ¡»ç¼±·®
  • median lethal dose =LD50
    50% Ä¡»ç·®(¡­öÈÞÝåÖ), Æò±ÕÄ¡»ç·®.
  • median lethal dose, MLD
    Áß¾ÓÄ¡»ç¼±·®
  • minimum lethal dose (MLD)
    ÃÖ¼ÒÄ¡»ç·®
  • tumor lethal dose
    Á¾¾çÄ¡»ç·®(ðþåËöÈÞÝåÖ)
  • minimal dose =minimum d.
    ÃÖ¼Ò·®(õÌá³åÖ).
  • minimal effective dose
    ÃÖ¼ÒÀ¯È¿·®.
  • minimal erythema dose
    ÃÖ¼ÒÈ«¹Ý·®(¡­ûõÚèåÖ).
  • minimal erythema dose
    ÃÖ¼ÒÈ«¹Ý·®(¡­ûõÚèåÖ)
  • minimal infecting dose
    ÃÖ¼Ò°¨¿°·®(õÌá³ÊïæøåÖ).
´ëÇÑÇØºÎÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Lethal gene
    Ä¡»çÀ¯ÀüÀÚ
    [¿¾ ¿ë¾î] Ä¡»çÀ¯ÀüÀÚ
´ëÇÑ»ýÈ­ÇкÐÀÚ»ý¹°ÇÐȸ ¿ë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • lethal dose
    Ä¡»ç·®(öÈÞÝÕá)
  • median lethal dose
    Á¤Áß Ä¡»ç·®(ïáñéöÈÞÝÕá)
  • minbimum lethal dose
    ÃÖ¼ÒÄ¡»ç·®(õÌá³öÈÞÝÕá)
  • minimal medium
    ÃÖ¼Ò¹èÁö(õÌá³ÛÆò¢)
  • minimal stable length
    ÃÖ¼Ò¾ÈÁ¤(õÌá³äÌïÒ) ±æÀÌ
  • aphasic lethal
    ºñ´Ü°èÀû(ÞªÓ«Í­îÜ) Ä¡»ç¼º(öÈÞÝàõ)
  • conditional lethal mutant
    Á¶°ÇºÎ Ä¡»çº¯ÀÌü(ðÉËìݾöÈÞÝܨì¶ô÷)
  • effective lethal phase
    À¯È¿ Ä¡»ç±â(êóüùöÈÞÝÑ¢)
  • lethal concentration
    Ä¡»ç³óµµ(öÈÞÝÒØÓø)
  • lethal gene
    Ä¡»çÀ¯ÀüÀÚ(öÈÞÝë¶îîí­)
  • lethal hit
    Ä¡»ç°¡°Ý(öÈÞÝʥ̪)
  • lethal mutation
    Ä¡»çº¯ÀÌ(öÈÞÝܨì¶)
  • lethal mutation model
    Ä¡»çº¯ÀÌ(öÈÞÝܨì¶)¸ðµ¨
  • lethal synthesis
    Ä¡»çÇÕ¼º(öÈÞÝùêà÷)
  • recessive lethal gene
    ¿­¼º Ä¡»çÀ¯ÀüÀÚ(Ö«àõöÈÞÝë¶îîí­)
KI ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • minimal effective dose
    ÃÖ¼ÒÀ¯È¿·®
  • half lethal dose
    ¹ÝÄ¡»ç·®
  • LD = lethal dose
    Ä¡»ç·®
  • lethal dose [=LD]
    Ä¡»ç·®
  • median lethal dose
    50%Ä¡»ç·®, Æò±ÕÄ¡»ç·®
  • minimal
    ÃÖ¼ÒÀÇ
  • minimal enhancement
    ¹Ì¹ÌÇÑÁ¶¿µÁõ°­, °æµµÀÇÁ¶¿µÁõ°­
  • lethal
    Ä¡»çÀÇ, Ä¡¸íÀûÀÎ
  • air dose
    °øÁß¼±·®, °ø±âÁß¼±·®
  • cumulative dose
    ÁýÀû¼±·®, ´©ÀûÁ¶»ç·®, ´©Àû¿ë·®, Ãàô¿ë·®
  • curative dose
    ġȿ·®
  • depth dose
    ½ÉºÎ¼±·®
  • dose rate
    ¼±·®·ü
  • fatal dose
    Ä¡»ç·®
  • maintenance dose
    À¯Áö¿ë·®
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
MLD manual lymph drainage; median lethal dose; metachromatic leukodystrophy; minimal lesion disease; min...
MRD maximum rate of depolarization; measles-rindenpest-distemper [virus group]; medical records departme...
ID identification; iditol dehydrogenase; immunodeficiency; immunodiffusion; immunoglobulin deficiency; ...
MPD main pancreatic duct; maximum permissible dose; mean population doubling; membrane potential differe...
LD labor and delivery; laboratory data; labyrinthine defect; lactate dehydrogenase; laser Doppler; lear...
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
MLC Minimal lethal concentrations
LD Lethal dose
LD50 Lethal dose
LD50 Lethal dose 50
MLD Minimum Lethal Dose
°æºÏ´ë Ä¡°ú´ëÇÐ ±¸°­³»°ú ±³½Ç »çÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
  • minimal dose
    ÃÖ¼Ò·®
  • mean lethal dose
    50% Ä¡»ç·®
  • Eagle`s minimal essential medium
    ÀÌ±Û ¹èÁö
    ¼¼Æ÷ ¹è¾ç¾×ÀÇ ÀÏÁ¾. 3Á¾·ùÀÇ ¾Æ¹Ì³ë»ê°ú 8Á¾·ùÀÇ ºñŸ¹ÎÀ» ÇÔÀ¯Çϰí ÀÖÀ¸¸ç º¸Åë Ç÷û 5% ÀÌÇÏ¿¡¼­ À¯Áö ¹èÁö·Î¼­ »ç¿ëµÇ°í 10-20%ÀÇ Ç÷û ÷°¡·Î ¸¹Àº ¼¼Æ÷´Â ±ØÈ÷ ¾çÈ£ÇÑ ¹ßÀ°À» ³ªÅ¸³½´Ù.
  • minimal
    ÃÖ¼ÒÀÇ
    °¡Àå °¡´É¼ºÀÌ ÀûÀº.
  • minimal enhancement
    ¹Ì¹ÌÇÑ Á¶¿µ Áõ°­, °æµµÀÇ Á¶¿µ Áõ°­
  • minimal identifiable odor
    ÃÖ¼Ò ºÐÇØ Ãë°¢
  • minimal requirement
    ÃÖ¼Ò ±Ô°Ý
  • minimal temperature
    ÃÖÀú ¿Âµµ
  • lethal catatonia
    ±Þ¼º Ä¡»ç¼º ±äÀ庴
  • lethal effect
    Ä¡»ç È¿°ú
  • lethal form
    Ä¡»çÀûÀÎ ÇüÅÂ
  • lethal midiane granuloma
    Áß½É Ä¡»ç À°¾ÆÁ¾
    ¾È¸éÀÇ Áß¾ÓÀÌ ÆÄ±«µÇ°í Á×À½¿¡ À̸£°Ô µÇ´Â µå¹® ±«»ç¼º À°¾ÆÁ¾.
  • lethal midline granuloma
    Ä¡»ç Á߽ɼ± À°¾ÆÁ¾, ¾Ç¼º Á¤Áß À°¾ÆÁõ
    ±«Àú¼º ºñ¿°.
  • lethal poison
    Ä¡»ç µ¶
  • lethal toxin
    Ä¡»ç µ¶¼Ò
    ½Ä¹°À̳ª µ¿¹° µîÀÇ ¾î¶² ¿ä¼Ò°¡ »ç¶÷À̳ª µ¿¹°¿¡°Ô Ä¡¸íÀûÀÎ °á°ú¸¦ ÀÏÀ¸Å³ ¶§ ±×·± ¿ä¼Ò¸¦ Ä¡»ç µ¶¼Ò¶ó°í ÇÑ´Ù.
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
minimal lethal dose <pharmacology> The minimal dose of a toxic substance or infectious agent that is lethal, as assayed in various experimental animals (e.g., the least amount of diphtheria toxin that, on an average, kills a 250-g guinea pig within 96 hours after subcutaneous inoculation).
When followed by a subscript (generally "MLD50"), denotes the minimal dose that is lethal to a certain percentage (e.g., 50%) of animals so assayed, LD05.
See: lethal dose.
(05 Mar 2000)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
minimal dose <pharmacology> The smallest amount of a drug or physical procedure that will produce a desired physiologic effect in an adult.
(05 Mar 2000)
minimal infecting dose <microbiology> The smallest quantity of infectious material regularly producing infection; usually expressed as I.D.50, the quantity causing infection in 50% of a suitable series of animals or cells (cell cultures).
(05 Mar 2000)
minimal reacting dose The minimal dose of a toxic substance causing a reaction, as manifested in the skin of a series of susceptible test animals; the assay is based on the development of a characteristic, minimal but definite, "standard," focal inflammation (congestion and oedema, induration, degenerative changes, and desquamation of epidermal cells).
(05 Mar 2000)
lethal dose <pharmacology> The amount, or dosage, of a toxin necessary to cause death.
(16 Mar 1998)
lethal dose 50 <pharmacology> The amount, or dosage, of a toxin necessary to kill 50% of the experimental subjects.
(16 Mar 1998)
minimal Smallest or least, the smallest possible.
Origin: L. Minimus = least
(18 Nov 1997)
minimal air The volume of gas that remains in the lungs and cannot be expelled after they have been removed from the body, or after the chest has been opened.
(05 Mar 2000)
minimal alveolar concentration The end-alveolar concentration of an inhalation anaesthetic which prevents somatic response to a painful stimulus in 50% of individuals; an index of relative potency of inhalation anaesthetics.
Synonym: minimal anaesthetic concentration.
(05 Mar 2000)
minimal amplitude nystagmus Nystagmus of so small an amplitude that it is not detected by the usual clinical tests.
Synonym: minimal amplitude nystagmus.
Origin: micro-+ G. Nystagmos, a nodding
(05 Mar 2000)
minimal anaesthetic concentration The end-alveolar concentration of an inhalation anaesthetic which prevents somatic response to a painful stimulus in 50% of individuals; an index of relative potency of inhalation anaesthetics.
Synonym: minimal anaesthetic concentration.
(05 Mar 2000)
minimal brain dysfunction An inability to control behaviour due to difficulty in processing neural stimuli.
(12 Dec 1998)
minimal-change disease <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure.
This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness.
It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown.
Risk factors include a history for a immune disorder, recent immunisation or a bee sting.
Diagnosis is made by renal biopsy.
Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented.
Synonym: lipoid nephrosis
(27 Sep 1997)
minimal-change nephrotic syndrome <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure.
This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness.
It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown.
Risk factors include a history for a immune disorder, recent immunisation or a bee sting.
Diagnosis is made by renal biopsy.
Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented.
Synonym: lipoid nephrosis
(27 Sep 1997)
minimal deviation melanoma <dermatology, tumour> A malignant melanoma showing less cytologic atypia than is usual in melanoma cells showing asymmetric expansile invasion of the dermis.
(05 Mar 2000)
minimal inhibitory concentration <microbiology, pharmacology> The lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro.
(05 Mar 2000)
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