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MC mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med...
M-C mineralocorticoid
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AME Apparent Mineralocorticoid Excess
MC Mineralocorticoid
MR Mineralocorticoid
MR Mineralocorticoid receptor
hMR human mineralocorticoid receptor
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    Mineralocorticoid antagonists [aldosterone antagonists]
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mineralocorticoid 1. <biochemistry> Any of the group of C21 corticosteroids, principally aldosterone, predominantly involved in the regulation of electrolyte and water balance through their effect on ion transport in epithelial cells of the renal tubules, resulting in retention of sodium and loss of potassium, some also possess varying degrees of glucocorticoid activity.
Their secretion is regulated principally by plasma volume, serum potassium concentration and angiotensin II and to a lesser extent by anterior pituitary ACTH.
2. <pharmacology> Of, pertaining to, having the properties of or resembling a mineralocorticoid.
(12 Jan 1998)
mineralocorticoids A group of hormones (the most important being aldosterone) that regulate the balance of water and electrolytes (ions such as sodium and potassium) in the body. The mineralocorticoid hormones act on the kidney (and specifically on the tubules of the kidney).
(12 Dec 1998)
mineralocorticoids, synthetic Synthetic steroids that mimic the activity of the mineralocorticoids obtained from the adrenal cortex, but differ in structure from the naturally occurring mineralocorticoids.
(12 Dec 1998)
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receptors, mineralocorticoid Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.
(12 Dec 1998)
hormone, mineralocorticoid A group of hormones, the most important being aldosterone, that regulate the balance of water and electrolytes (ions such as sodium and potassium) in the body. The mineralocorticoid hormones act specifically on the tubules of the kidney.
(12 Dec 1998)
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  • Mineralocorticoid Excess Syndrome, Apparent - »õâ A hereditary disease characterized by childhood onset HYPERTENSION, hypokalemic alkalosis, and low RENIN and ALDOSTERONE secretion. It results from a defect in the activity of the 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 enzyme which results in inadequate conversion of CORTISOL to CORTISONE. The build up of unprocessed cortisol to levels that stimulate MINERALOCORTICOID RECEPTORS creates the appearance of having excessive MINERALOCORTICOIDS.
    Synonyms :
  • Mineralocorticoids - »õâ A group of CORTICOSTEROIDS primarily associated with the water and electrolyte balance. This is accomplished through the effect on ION TRANSPORT in renal tubules, resulting in retention of sodium and loss of potassium. Mineralocorticoid secretion is itself regulated by PLASMA VOLUME, serum potassium, and ANGIOTENSIN II.
    Synonyms :
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mineralocorticoid hormone that is one of the steroids of the adrenal cortex that influences the metabolism of sodium and potassium
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mineralocorticoid hormone that is one of the steroids of the adrenal cortex that influences the metabolism of sodium and potassium
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