| MAP | malignant atrophic papulosis; mandibular angle plane; maturation-activated protein; maximal aerobic ... |
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| MT | magnetization transfer; malaria therapy; malignant teratoma; mammary tumor; mammilothalamic tract; m... |
| MTOC | microtubule organizing center; mitotic organizing center |
| MTP | maximum tolerated pressure; medial tibial plateau; median time to progression; metacarpophalangeal; ... |
| CDSC | Communicable Diseases Surveillance Centre [London] |
| MTOC | microtubule organising centre |
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| BOOP | Bronchiolitis Obliterans Organising Pneumonia |
| SOM | Self Organising Map |
| kMT | kinetochore microtubule |
| MAP-1 | Microtubule Associated Protein-1 |
| microtubule organising centre | <cell biology> Rather amorphous region of cytoplasm from which microtubules radiate. The pattern and number of microtubules is determined by the microtubule organising centre. The pericentriolar region is the major microtubule organising centre in animal cells, the basal body of a cilium is another example. Activity of microtubule organising centres can be regulated, but the mechanism is unclear. Acronym: MTOC (18 Nov 1997) |
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| organising centre | <cell biology> See microtubule organising centre. (18 Nov 1997) |
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| microtubule-organizing centre | A locus in interphase and mitotic cells from which most microtubules radiate; in the centre of this centre is the centriole; this centre determines the polarity of cellular microtubules. (05 Mar 2000) |
| microtubule | <cell biology> Cytoplasmic tubule, 25nm outside diameter with a 5nm thick wall. Made of tubulin heterodimers packed in a three start helix (or of 13 protofilaments looked at another way) and associated with various other proteins (MAPs, dynein, kinesin). Microtubules of the ciliary axoneme are more permanent than cytoplasmic and spindle microtubules. (18 Nov 1997) |
| microtubule-associated protein 1B kinase | <enzyme> Serine-threonine-specific protein kinase which acts on microtubule-associated protein 1b (map1b); activated by various mitogens; does not act on map2 Registry number: EC 2.7.10.- Synonym: map1b kinase (26 Jun 1999) |
| microtubule-associated protein-2 phosphatase | <enzyme> does not fit into any of the classes of protein phosphatases (types 1,2a,2b and 2c) involved in cellular regulation Registry number: EC 3.1.3.- Synonym: map-2 phosphatase (26 Jun 1999) |
| microtubule-associated proteins | <protein> High molecular weight proteins found in the microtubules of the cytoskeletal system. Under certain conditions they are required for tubulin assembly into the microtubules and stabilise the assembled microtubules. Acronym: MAP (12 Dec 1998) |
| subpellicular microtubule | A microtubule lying beneath the unit membrane (pellicle) of many protozoans, often as a palisade of longitudinally arranged fibrils connected by fine lateral bridges that support the external cell form; in certain sporozoan stages a fixed number of microtubule's are found, extending longitudinally from the polar ring. Synonym: subpellicular fibril. (05 Mar 2000) |
| doublet microtubule | <cell biology> Microtubules of the axoneme. The outer nine sets are often referred to as doublet microtubules, although only one the A tubule) is complete and has 13 protofilaments. The B tubule has only 10 or 11 protofilaments and shares the remainder with the A tubule. A and B tubules differ in their stability and in the other proteins attached periodically to them, it is the dynein affixed to the A tubule attaching and detaching from the B tubule of the adjacent doublet that generates sliding movement in the axoneme. (18 Nov 1997) |
| active centre | The part of a macromolecule at which a substrate or ligand, upon binding, produces biological activity; for an enzyme, this is the catalytic centre, the site on an enzyme that catalyses the reaction. (05 Mar 2000) |
| anospinal centre | The centre in the spinal cord that controls the contraction of the anal sphincter. (05 Mar 2000) |
| asymmetric centre | <chemistry> Same as a chiral centre, a tetrahedral carbon atom that bears four different substituents. (09 Jan 1998) |
| Broca's centre | The posterior part of the inferior frontal gyrus of the left or dominant hemisphere, corresponding approximately to Brodmann's area 44; Broca identified this region as an essential component of the motor mechanisms governing articulated speech. Synonym: Broca's area, Broca's field, motor speech centre. (05 Mar 2000) |
| Budge's centre | The preganglionic motor neurons in the first thoracic segment of the spinal cord which give rise to the sympathetic innervation of the dilator muscle of the eye's pupil. Synonym: Budge's centre. (05 Mar 2000) |
| vasomotor centre | Diffuse area of the reticular formation in the lateral medulla containing neurons that control vascular tone; consists of separate vasodepressor and vasopressor areas. (05 Mar 2000) |
| reaction centre | <plant biology> The site in the chloroplast that receives the energy trapped by chlorophyll and accessory pigments and initiates the electron transfer process. A photosynthetic complex containing chlorophyll (or bacteriochlorophyll) and other components, within which occurs the initial electron transfer reactions of photophosphorylation. (09 Oct 1997) |
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