| MTHFR | 10-Methylenetetrahydrofolate reductase |
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| methylenetetrahydrofolate dehydrogenase | <enzyme> Catalyses the oxidation of methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate. Includes EC 1.5.1.15 which uses NAD+. Chemical name: 5,10-Methylenetetrahydrofolate:NADP+ oxidoreductase Registry number: EC 1.5.1.5 (12 Dec 1998) |
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| formyl-methenyl-methylenetetrahydrofolate synthetase | <chemical> Trifunctional enzyme which contains EC 6.3.4.3, formyltetrahydrofolate synthetase, plus EC 3.5.4.9, methenyltetrahydrofolate cyclohydrolase, and EC 1.5.1.5, methylenetetrahydrofolate dehydrogenase as a complex in sheep liver Chemical name: synthetase, formyl-methenyl-methylenetetrahydrofolate Synonym: c1-thf synthase, c1-tetrahydrofolate synthase, formyl-methenyl-methylenetetrahydrofolate synthetase (combined), c-1-tetrahydrofolate synthetase, nadp-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase (26 Jun 1999) |
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Synonyms : 5, 10-Methylenetetrahydrofolate:NAD Oxidoreductase, Methylenetetrahydrofolate Dehydrogenase (NAD), NADH-Dependent 5, 10-Methylenetetrahydrofolate Reductase, 5, 10 Methylenetetrahydrofolate:NAD Oxidoreductase, Oxidoreductase, 5, 10-Methylenetetrahydrofolate:NAD
Synonyms : Methylenetetrahydrofolate Dehydrogenase, Dehydrogenase, Methylenetetrahydrofolate
Synonyms : 5, 10-Methylenetetrahydrofolate Reductase (NADPH), Methylene Tetrahydrofolate Reductase, Methylenetetrahydrofolate Reductase, Methylenetetrahydrofolate Reductase (NADPH), Tetrahydrofolate Reductase, Methylene
| methylenetetrahydrofolate (THF) reductase deficiency |
the most common genetic aminoacidopathy of folate metabolism; the chief biochemical finding is homocystinuria with normal levels of plasma methionine; the chief clinical sign is CNS damage.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| methylenetetrahydrofolate dehydrogenase (NADP+) |
[EC 1.5.1.5] an enzyme activity of the oxidoreductase class that catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate, using NADP+ as an electron acceptor. The reaction occurs in the system of folate-mediated one-carbon transfer reactions. The enzyme activity is part of a trifunctional enzyme that also includes methenyltetrahydrofolate cyclohydrolase and formatetetrahydrofolate ligase activities.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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