| MNTI | Melanotic neuroectodermal tumor of infancy |
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| ameloblastoma | <oncology, tumour> A malignant jaw tumour (adamantinoma) which stems from the ameloblasts, cells which form tooth enamel. (09 Oct 1997) |
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| pigmented ameloblastoma | A benign neoplasm of neuroectodermal origin that most often involves the anterior maxilla of infants in the first year of life. It presents clinically as a rapidly growing blue-black lesion producing a destructive radiolucency; histologically, it is characterised by small round undifferentiated tumour cells interspersed with larger polyhedral melanin-producing cells arranged in an alveolar configuration. Synonym: melanoameloblastoma, pigmented ameloblastoma, pigmented epulis, progonoma of jaw, retinal anlage tumour. (05 Mar 2000) |
| pituitary ameloblastoma | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| melanotic | 1. Pertaining to the presence, normal or pathologic, of melanin. 2. Relating to or characterised by melanosis. (05 Mar 2000) |
| melanotic carcinoma | <tumour> Obsolete term for melanoma. (05 Mar 2000) |
| melanotic freckle | A brown or black mottled, irregularly outlined, slowly enlarging lesion resembling a lentigo in which there are increased numbers of scattered atypical melanocytes in the epidermis, usually occurring on the face of older persons; after many years the dermis may be invaded and the lesion is then termed lentigo maligna melanoma. Synonym: Hutchinson's freckle, melanotic freckle. (05 Mar 2000) |
| melanotic neuroectodermal tumour of infancy | A benign neoplasm of neuroectodermal origin that most often involves the anterior maxilla of infants in the first year of life. It presents clinically as a rapidly growing blue-black lesion producing a destructive radiolucency; histologically, it is characterised by small round undifferentiated tumour cells interspersed with larger polyhedral melanin-producing cells arranged in an alveolar configuration. Synonym: melanoameloblastoma, pigmented ameloblastoma, pigmented epulis, progonoma of jaw, retinal anlage tumour. (05 Mar 2000) |
| melanotic pigment | <protein> Pigments largely of animal origin. High molecular weight polymers of indole quinone. Colours include black/brown, yellow, red and violet. Found in feathers, cuttle ink, human skin, hair and eyes and in cellular immune responses and wound healing in arthropods. (18 Nov 1997) |
| melanotic progonoma | A pigmented hairy nevus. (05 Mar 2000) |
| melanotic whitlow | <tumour> A melanoma beginning in the skin at the border of or beneath the nail. Synonym: melanotic whitlow. (05 Mar 2000) |
| hutchinson's melanotic freckle | A cutaneous malignant melanoma found most often on the sun-exposed areas of the skin, especially the face, which begins as a circumscribed, macular patch of mottled pigmentation, showing shades of dark brown, tan, or black, and enlarges by lateral growth before dermal invasion occurs. This type is the slowest growing, has the least tendency to metastasize, and seems to be the least aggressive form of malignant melanoma. Patients are commonly in their sixth or seventh decade. (12 Dec 1998) |
| neuroectodermal tumour, melanotic | A benign, rapidly growing, deeply pigmented tumour of the jaw and occasionally of other sites, consisting of an infiltrating mass of cells arranged in an alveolar pattern, and occurring almost exclusively in infants. Its source of origin is in dispute, the various theories giving rise to its several names. (12 Dec 1998) |
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