| MEN | Multiple Endocrine Neoplasia ; AD Trait 1. MEN Type I(= Wermer Syndro... |
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| PBT | Paul-Bunnell test; phenacetin breath test; piebald trait; profile-based therapy |
| PTD | percutaneous transluminal dilatation; permanent total disability; personality trait disorder; preter... |
| SCT | secretin; sex chromatin test; sexual compatibility test; sickle-cell trait; sperm cytotoxicity; spin... |
| STAI | State Trait Anxiety Inventory |
| MAS | Marker Assisted Selection |
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| OMP | Olfactory Marker Protein |
| SMP 30 | Senescence marker protein 30 |
| SMC | Supernumerary Marker Chromosome |
| Lin | lineage marker |
| marker trait | A trait that may be of little importance in itself but which by association, linkage, or other means facilitates the detection, anticipation, or understanding of a disease or (for genetic diseases) the localization of the causative gene on the karyotype. (05 Mar 2000) |
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| allotypic marker | Synonym: allotype. (05 Mar 2000) |
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| Bombay trait | A rare recessive trait at a locus that ordinarily manufactures H substance, the precursor from which the A and B phenotypes are elaborated; the mutant causes failure to produce H substance and no matter what the genotype at the ABO locus, the phenotype is O. The Bombay phenomenon is epistatic to the ABO locus. Origin: Bombay, India, where first reported (05 Mar 2000) |
| galtonian trait | A quantitative genetic trait due to contributions from many more of less equally important loci that resembles a continuous trait. (05 Mar 2000) |
| genetic marker | A gene which has an easily identifiable phenotype so that one can tell apart cells or individuals which have the gene and those which do not have it. Such a gene can also be used as a probe to mark cell nuclei or chromosomes so that they can easily be isolated or identified from other nuclei or chromosomes later. (09 Oct 1997) |
| recessive trait | See: dominance of traits. (05 Mar 2000) |
| marker | An identifiable physical location on a chromosome (for example, restriction enzyme cuttingsite, gene) whose inheritance can bemonitored. Markers can beexpressed regions of DNA (genes) or some segment of DNA with no knowncoding function but whose pattern of inheritance can be determined. See: restriction fragment length polymorphism. (09 Oct 1997) |
| marker chromosome | An abnormal chromosome that is distinctive in appearance but not fully identified. For example, the fragile x chromosome was once called the marker x. (12 Dec 1998) |
| marker enzyme | <enzyme> An enzyme that is used to identify a specific cell type, cell organelle, or cell component. (05 Mar 2000) |
| marker gene | Gene that confers some readily detectable phenotype on cells carrying the gene, either in culture or in transgenic or chimeric organisms. Gene could be an enzymic reporter gene, a selectable marker conferring antibiotic resistance or a cell membrane protein with a characteristic epitope. (18 Nov 1997) |
| marker locus | A locus on a chromosome or in a stretch of DNA that can be identified (e.g., a restriction fragment length polymorphism) and can serve in linkage analysis and in the isolation of a disease gene. See: linkage marker. (05 Mar 2000) |
| marker, object | <microscopy> A small abrasive stylus, set in a rotating holder mounted on the lower end of the drawtube. The desired part of the specimen is placed in the centre of the field, and the abrasive point is pressed against the slide or cover, and rotated. It describes a tiny circle around the desired object field. (05 Aug 1998) |
| categorical trait | <genetics> A feature that can conveniently and effectively be analyzed by sorting into classes either because there is no satisfactory way of measuring it (as with blood groups) or because it falls into natural classes so that the variation among classes far exceeds that within classes (e.g., the phenotypic effects of many enzyme polymorphisms); existence of categories suggests but does not prove the operation of a major, simple, underlying cause. Synonym: qualitative trait. (05 Mar 2000) |
| cell marker | <cell biology> Biochemical or genetic characteristics which distinguish and discriminate between different cell types. (26 Mar 1998) |
| cell surface marker | <cell biology> Any molecule characteristic of the plasma membrane of a cell or in some cases of a specific cell type. 5' nucleotidase and Na/K ATPase are often used as plasma membrane markers. (26 Mar 1998) |
| penetrant trait | A trait that in the appropriate genotypes is phenotypically manifest; strictly, it is the trait that is penetrant, not the gene. See: penetrance. (05 Mar 2000) |
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